Snx4 (sorting nexin 4) - Rat Genome Database

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Gene: Snx4 (sorting nexin 4) Heterocephalus glaber
Analyze
Symbol: Snx4
Name: sorting nexin 4
RGD ID: 18915151
Description: ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); insulin receptor binding (ortholog); leptin receptor binding (ortholog); INVOLVED IN endocytic recycling (ortholog); positive regulation of histamine secretion by mast cell (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); Familial Thoracic Aortic Aneurysm 7 (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic dynein complex (ortholog); early endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sorting nexin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247311,522,098 - 1,586,066 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247311,522,467 - 1,585,793 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Snx4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247311,522,098 - 1,586,066 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247311,522,467 - 1,585,793 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SNX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383125,446,650 - 125,520,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3125,446,650 - 125,520,202 (-)EnsemblGRCh38hg38GRCh38
GRCh373125,165,494 - 125,239,046 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363126,648,184 - 126,721,748 (-)NCBINCBI36Build 36hg18NCBI36
Build 343126,648,184 - 126,721,748NCBI
Celera3123,575,104 - 123,648,748 (-)NCBICelera
Cytogenetic Map3q21.2NCBI
HuRef3122,541,455 - 122,614,640 (-)NCBIHuRef
CHM1_13125,128,503 - 125,202,079 (-)NCBICHM1_1
T2T-CHM13v2.03128,173,305 - 128,246,821 (-)NCBIT2T-CHM13v2.0
Snx4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,071,826 - 33,119,932 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,071,812 - 33,120,639 (+)EnsemblGRCm39 Ensembl
GRCm381633,251,456 - 33,299,562 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,251,442 - 33,300,269 (+)EnsemblGRCm38mm10GRCm38
MGSCv371633,251,542 - 33,299,648 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361633,171,203 - 33,219,309 (+)NCBIMGSCv36mm8
Celera1633,735,288 - 33,783,365 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1623.77NCBI
Snx4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81180,965,965 - 81,023,234 (-)NCBIGRCr8
mRatBN7.21167,460,872 - 67,518,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1167,460,870 - 67,518,174 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1176,297,930 - 76,355,201 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01168,959,778 - 69,017,046 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01167,987,014 - 68,044,293 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,693,381 - 70,753,620 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,693,366 - 70,753,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,779,997 - 73,836,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,283,047 - 69,340,448 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11169,340,633 - 69,398,051 (-)NCBI
Celera1166,908,596 - 66,965,885 (-)NCBICelera
Cytogenetic Map11q22NCBI
Snx4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542724,520,125 - 24,579,589 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542724,520,125 - 24,579,589 (-)NCBIChiLan1.0ChiLan1.0
SNX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22123,443,042 - 123,516,580 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13123,447,819 - 123,521,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03122,578,527 - 122,652,007 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13129,443,369 - 129,515,917 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3129,443,369 - 129,515,917 (-)Ensemblpanpan1.1panPan2
SNX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13328,413,586 - 28,468,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3328,419,128 - 28,469,488 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3328,435,320 - 28,505,544 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03328,645,502 - 28,715,994 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3328,645,503 - 28,715,999 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13328,443,347 - 28,513,160 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03328,488,217 - 28,558,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03329,107,848 - 29,178,056 (-)NCBIUU_Cfam_GSD_1.0
Snx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602125,954,209 - 125,964,379 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004937215127,074 - 137,281 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13134,824,043 - 134,905,359 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113134,824,028 - 134,903,765 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SNX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12255,311,896 - 55,389,174 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2255,311,933 - 55,389,349 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041110,924,615 - 111,001,623 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020325   ⟹   ENSHGLP00000020124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247311,522,098 - 1,586,066 (-)Ensembl
RefSeq Acc Id: XM_004835223   ⟹   XP_004835280
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247311,522,467 - 1,585,793 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004835280 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99188 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020124
GenBank Protein JAN96090 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004835280   ⟸   XM_004835223
- UniProtKB: G5AQ78 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020124   ⟸   ENSHGLT00000020325


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014404 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020325 ENTREZGENE
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  PX_SNX4 UniProtKB/TrEMBL
  SNX4 UniProtKB/TrEMBL
  SNX4_BAR UniProtKB/TrEMBL
KEGG Report hgl:101704723 UniProtKB/TrEMBL
NCBI Gene Snx4 ENTREZGENE
PANTHER PTHR46596 UniProtKB/TrEMBL
  SORTING NEXIN-4 UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
SMART SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF64268 UniProtKB/TrEMBL
UniProt G5AQ78 ENTREZGENE, UniProtKB/TrEMBL