Naf1 (nuclear assembly factor 1 ribonucleoprotein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Naf1 (nuclear assembly factor 1 ribonucleoprotein) Heterocephalus glaber
Analyze
Symbol: Naf1
Name: nuclear assembly factor 1 ribonucleoprotein
RGD ID: 18913895
Description: ENCODES a protein that exhibits identical protein binding (ortholog); telomerase RNA binding (ortholog); INVOLVED IN positive regulation of telomerase RNA localization to Cajal body (ortholog); positive regulation of telomere maintenance via telomere lengthening (ortholog); RNA stabilization (ortholog); ASSOCIATED WITH melanoma (ortholog); pulmonary fibrosis (ortholog); Pulmonary Fibrosis and/or Bone Marrow Failure Syndrome, Telomere-Related, 7 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: H/ACA ribonucleoprotein complex non-core subunit NAF1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475813,685,988 - 13,724,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475813,686,660 - 13,724,061 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Naf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475813,685,988 - 13,724,375 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475813,686,660 - 13,724,061 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384163,103,929 - 163,166,890 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4163,110,073 - 163,166,890 (-)EnsemblGRCh38hg38GRCh38
GRCh374164,047,860 - 164,088,042 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364164,269,271 - 164,307,523 (-)NCBINCBI36Build 36hg18NCBI36
Celera4161,380,432 - 161,420,296 (-)NCBICelera
Cytogenetic Map4q32.2NCBI
HuRef4159,801,831 - 159,842,041 (-)NCBIHuRef
CHM1_14164,024,307 - 164,064,522 (-)NCBICHM1_1
T2T-CHM13v2.04166,457,003 - 166,514,759 (-)NCBIT2T-CHM13v2.0
Naf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39867,312,594 - 67,343,216 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl867,312,869 - 67,343,216 (+)EnsemblGRCm39 Ensembl
GRCm38866,859,943 - 66,890,564 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl866,860,217 - 66,890,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv37869,384,116 - 69,414,463 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36869,789,206 - 69,819,550 (+)NCBIMGSCv36mm8
Celera869,419,949 - 69,450,184 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
cM Map833.18NCBI
Naf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81627,604,228 - 27,634,963 (-)NCBIGRCr8
mRatBN7.21622,837,583 - 22,868,320 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1622,837,588 - 22,868,293 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1626,204,141 - 26,234,903 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01629,638,815 - 29,669,578 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01625,569,479 - 25,600,243 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01624,582,000 - 24,612,773 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1624,578,678 - 24,612,732 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01624,465,726 - 24,496,546 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,533,261 - 24,564,544 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11624,530,001 - 24,564,464 (-)NCBI
Celera1622,967,325 - 22,998,036 (-)NCBICelera
Cytogenetic Map16p14NCBI
Naf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540341,804,451 - 41,839,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540341,804,273 - 41,840,232 (+)NCBIChiLan1.0ChiLan1.0
NAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23160,934,269 - 160,977,306 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14161,296,787 - 161,340,283 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04155,383,245 - 155,425,479 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14167,173,673 - 167,214,065 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4167,157,770 - 167,214,065 (-)Ensemblpanpan1.1panPan2
NAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11559,430,809 - 59,470,306 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1559,795,437 - 59,836,218 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01560,189,290 - 60,229,917 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1560,189,302 - 60,229,982 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11559,423,803 - 59,464,193 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01559,514,283 - 59,554,760 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01559,883,000 - 59,923,746 (-)NCBIUU_Cfam_GSD_1.0
Naf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494316,139,528 - 16,177,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365552,392,721 - 2,426,759 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365552,392,202 - 2,428,857 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl851,968,483 - 52,012,927 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1851,972,288 - 52,012,818 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2855,108,325 - 55,148,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17109,578,476 - 109,617,114 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7109,576,073 - 109,617,122 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603789,381,696 - 89,423,051 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021046   ⟹   ENSHGLP00000020843
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475813,685,988 - 13,724,375 (+)Ensembl
RefSeq Acc Id: XM_004848238   ⟹   XP_004848295
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475813,686,660 - 13,724,061 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004848295 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08862 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020843
  ENSHGLP00100010106
Reference Protein Sequences
RefSeq Acc Id: XP_004848295   ⟸   XM_004848238
- UniProtKB: G5BHV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020843   ⟸   ENSHGLT00000021046


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014899 Ensembl, ENTREZGENE
  ENSHGLG00100007507 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000021046 ENTREZGENE
  ENSHGLT00100010226 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.230 UniProtKB/TrEMBL
InterPro Gar1/Naf1_Cbf5-bd_sf UniProtKB/TrEMBL
  H/ACA_rnp_Gar1/Naf1 UniProtKB/TrEMBL
  Naf1 UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
KEGG Report hgl:101696610 UniProtKB/TrEMBL
NCBI Gene Naf1 ENTREZGENE
PANTHER H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 UniProtKB/TrEMBL
  PTHR31633 UniProtKB/TrEMBL
Pfam Gar1 UniProtKB/TrEMBL
Superfamily-SCOP SSF50447 UniProtKB/TrEMBL
UniProt G5BHV1 ENTREZGENE, UniProtKB/TrEMBL