Dcaf1 (DDB1 and CUL4 associated factor 1) - Rat Genome Database

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Gene: Dcaf1 (DDB1 and CUL4 associated factor 1) Heterocephalus glaber
Analyze
Symbol: Dcaf1 (Ensembl: VPRBP)
Name: DDB1 and CUL4 associated factor 1
RGD ID: 18911767
Description: ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN B cell differentiation (ortholog); cell competition in a multicellular organism (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN COP9 signalosome (ortholog); fibrillar center (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DDB1- and CUL4-associated factor 1; protein VPRBP; VPRBP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,176,828 - 5,240,680 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,176,828 - 5,245,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dcaf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,176,828 - 5,240,680 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,176,828 - 5,245,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DCAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,395,867 - 51,505,639 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,395,867 - 51,500,015 (-)EnsemblGRCh38hg38GRCh38
GRCh37351,433,298 - 51,534,031 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,408,338 - 51,509,041 (-)NCBINCBI36Build 36hg18NCBI36
Celera351,407,652 - 51,511,665 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef351,490,525 - 51,594,696 (-)NCBIHuRef
CHM1_1351,385,206 - 51,485,919 (-)NCBICHM1_1
T2T-CHM13v2.0351,426,284 - 51,536,063 (-)NCBIT2T-CHM13v2.0
Dcaf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,691,354 - 106,758,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,699,073 - 106,758,191 (+)EnsemblGRCm39 Ensembl
GRCm389106,814,169 - 106,880,992 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,821,874 - 106,880,992 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,724,307 - 106,783,323 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,680,077 - 106,738,533 (+)NCBIMGSCv36mm8
Celera9106,446,540 - 106,505,051 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.98NCBI
Dcaf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88116,344,927 - 116,419,329 (+)NCBIGRCr8
mRatBN7.28107,466,229 - 107,540,633 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,474,312 - 107,540,627 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8113,097,883 - 113,164,276 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08111,297,067 - 111,363,450 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08109,139,836 - 109,206,229 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,538,365 - 115,615,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,546,712 - 115,615,282 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,898,496 - 114,974,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,034,908 - 112,102,320 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18112,061,887 - 112,120,790 (+)NCBI
Celera8106,786,375 - 106,852,580 (+)NCBICelera
Cytogenetic Map8q32NCBI
Dcaf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,085,386 - 3,154,671 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,085,386 - 3,153,952 (-)NCBIChiLan1.0ChiLan1.0
DCAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,380,823 - 51,490,357 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,385,603 - 51,494,324 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,326,589 - 51,430,217 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1352,560,427 - 52,668,919 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl352,560,427 - 52,663,807 (-)Ensemblpanpan1.1panPan2
DCAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12038,109,974 - 38,187,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2038,125,078 - 38,187,107 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,089,540 - 38,167,146 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,458,824 - 38,536,454 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2038,464,033 - 38,536,453 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,822,249 - 37,899,846 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02038,226,332 - 38,304,159 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,516,174 - 38,593,797 (+)NCBIUU_Cfam_GSD_1.0
Dcaf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,025,750 - 66,101,560 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365292,786,252 - 2,856,967 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365292,786,252 - 2,856,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1333,670,977 - 33,750,772 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11333,670,976 - 33,750,872 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21336,900,767 - 36,968,157 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12212,736,784 - 12,843,762 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2212,739,665 - 12,823,363 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041154,127,859 - 154,231,832 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019848   ⟹   ENSHGLP00000019652
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247305,176,828 - 5,240,680 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000019849   ⟹   ENSHGLP00000019653
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247305,177,341 - 5,232,501 (-)Ensembl
RefSeq Acc Id: XM_021238571   ⟹   XP_021094230
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,245,548 (-)NCBI
RefSeq Acc Id: XM_021238589   ⟹   XP_021094248
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,245,540 (-)NCBI
RefSeq Acc Id: XM_021238617   ⟹   XP_021094276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,240,026 (-)NCBI
RefSeq Acc Id: XM_021238652   ⟹   XP_021094311
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,245,505 (-)NCBI
RefSeq Acc Id: XM_021238683   ⟹   XP_021094342
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,234,420 (-)NCBI
RefSeq Acc Id: XM_021238720   ⟹   XP_021094379
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,240,003 (-)NCBI
RefSeq Acc Id: XM_021238745   ⟹   XP_021094404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,189,172 - 5,245,544 (-)NCBI
RefSeq Acc Id: XM_021238781   ⟹   XP_021094440
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247305,176,828 - 5,245,548 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021094440   ⟸   XM_021238781
- Peptide Label: isoform X5
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094230   ⟸   XM_021238571
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094248   ⟸   XM_021238589
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094311   ⟸   XM_021238652
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094276   ⟸   XM_021238617
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094379   ⟸   XM_021238720
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094342   ⟸   XM_021238683
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094404   ⟸   XM_021238745
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J7V8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019653   ⟸   ENSHGLT00000019849
RefSeq Acc Id: ENSHGLP00000019652   ⟸   ENSHGLT00000019848


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014072 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019848 ENTREZGENE
  ENSHGLT00000019849 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  LisH UniProtKB/TrEMBL
  VPRBP/DCAF1 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101720808 UniProtKB/TrEMBL
NCBI Gene Dcaf1 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 1 UniProtKB/TrEMBL
  PTHR13129 UniProtKB/TrEMBL
PROSITE LISH UniProtKB/TrEMBL
SMART LisH UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A0P6J7V8 ENTREZGENE, UniProtKB/TrEMBL