Hcrtr1 (hypocretin receptor 1) - Rat Genome Database

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Gene: Hcrtr1 (hypocretin receptor 1) Heterocephalus glaber
Analyze
Symbol: Hcrtr1
Name: hypocretin receptor 1
RGD ID: 18911746
Description: ENCODES a protein that exhibits orexin receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); neuropeptide signaling pathway (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); genetic disease (ortholog); withdrawal disorder (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: orexin receptor type 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476414,862,397 - 14,869,739 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476414,861,672 - 14,872,728 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hcrtr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476414,862,397 - 14,869,739 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476414,861,672 - 14,872,728 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HCRTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38131,617,689 - 31,634,492 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl131,617,686 - 31,632,518 (+)EnsemblGRCh38hg38GRCh38
GRCh37132,083,290 - 32,093,214 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36131,857,228 - 31,865,301 (+)NCBINCBI36Build 36hg18NCBI36
Build 34131,753,733 - 31,761,807NCBI
Celera130,352,534 - 30,362,141 (+)NCBICelera
Cytogenetic Map1p35.2NCBI
HuRef130,200,818 - 30,210,425 (+)NCBIHuRef
CHM1_1132,199,098 - 32,208,715 (+)NCBICHM1_1
T2T-CHM13v2.0131,475,343 - 31,490,165 (+)NCBIT2T-CHM13v2.0
Hcrtr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394130,024,010 - 130,033,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4130,024,010 - 130,033,152 (-)EnsemblGRCm39 Ensembl
GRCm384130,130,217 - 130,139,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4130,130,217 - 130,139,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv374129,807,461 - 129,816,406 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364129,632,521 - 129,641,466 (-)NCBIMGSCv36mm8
Celera4128,464,692 - 128,473,445 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map463.43NCBI
Hcrtr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85147,761,392 - 147,771,846 (-)NCBIGRCr8
mRatBN7.25142,477,214 - 142,486,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5142,477,214 - 142,486,674 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5145,177,816 - 145,187,460 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05146,947,628 - 146,957,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05146,945,402 - 146,954,867 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05148,346,029 - 148,355,404 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5148,346,031 - 148,355,406 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05152,064,507 - 152,073,882 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45149,160,739 - 149,170,736 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15149,170,777 - 149,180,775 (-)NCBI
Celera5140,944,936 - 140,954,306 (-)NCBICelera
Cytogenetic Map5q36NCBI
Hcrtr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545210,026,464 - 10,036,186 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545210,026,464 - 10,036,267 (+)NCBIChiLan1.0ChiLan1.0
HCRTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21195,201,771 - 195,212,007 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11194,323,439 - 194,333,994 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0130,901,772 - 30,913,633 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1131,918,650 - 31,928,290 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl131,919,980 - 31,928,290 (+)Ensemblpanpan1.1panPan2
HCRTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,484,776 - 69,493,956 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl269,480,199 - 69,494,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,064,201 - 66,072,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0270,050,261 - 70,058,799 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl270,045,316 - 70,057,436 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,886,002 - 66,894,539 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,882,448 - 67,890,972 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,881,857 - 68,890,396 (-)NCBIUU_Cfam_GSD_1.0
Hcrtr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505848,908,833 - 48,920,670 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647414,735,638 - 14,742,854 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647414,735,654 - 14,744,112 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HCRTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl688,139,498 - 88,154,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1688,139,623 - 88,149,531 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2681,853,666 - 81,864,501 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HCRTR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120101,241,742 - 101,252,841 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20101,243,586 - 101,251,349 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603315,439,702 - 15,447,823 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019668   ⟹   ENSHGLP00000019475
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,862,397 - 14,869,739 (+)Ensembl
RefSeq Acc Id: XM_004850820   ⟹   XP_004850877
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,861,672 - 14,872,728 (+)NCBI
RefSeq Acc Id: XM_004850821   ⟹   XP_004850878
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,862,519 - 14,872,728 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850877 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850878 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019475
GenBank Protein JAO02794 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004850877   ⟸   XM_004850820
- UniProtKB: A0A0P6JY74 (UniProtKB/TrEMBL),   G5BUA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850878   ⟸   XM_004850821
- UniProtKB: A0A0P6JY74 (UniProtKB/TrEMBL),   G5BUA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019475   ⟸   ENSHGLT00000019668


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013949 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019668 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Orexin_rcpt UniProtKB/TrEMBL
  Orexin_rcpt_1 UniProtKB/TrEMBL
KEGG Report hgl:101704562 UniProtKB/TrEMBL
NCBI Gene Hcrtr1 ENTREZGENE
PANTHER G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  LEUCOKININ RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OREXIN1R UniProtKB/TrEMBL
  OREXINR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0P6JY74 ENTREZGENE, UniProtKB/TrEMBL
  G5BUA4 ENTREZGENE, UniProtKB/TrEMBL