Fnip2 (folliculin interacting protein 2) - Rat Genome Database

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Gene: Fnip2 (folliculin interacting protein 2) Heterocephalus glaber
Analyze
Symbol: Fnip2
Name: folliculin interacting protein 2
RGD ID: 18911491
Description: ENCODES a protein that exhibits ATPase inhibitor activity (inferred); protein-folding chaperone binding (inferred); INVOLVED IN intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Leukoencephalopathies (ortholog); FOUND IN centriolar satellite (ortholog); cytosol (ortholog); FNIP-folliculin RagC/D GAP (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Folliculin-interacting protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248483,756,247 - 3,827,288 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248483,739,677 - 3,826,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Fnip2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248483,756,247 - 3,827,288 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248483,739,677 - 3,826,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FNIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384158,769,026 - 158,908,050 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4158,769,026 - 158,908,050 (+)EnsemblGRCh38hg38GRCh38
GRCh374159,690,178 - 159,829,202 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364159,909,632 - 160,047,408 (+)NCBINCBI36Build 36hg18NCBI36
Celera4157,031,205 - 157,168,989 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4155,440,385 - 155,578,054 (+)NCBIHuRef
CHM1_14159,666,653 - 159,804,420 (+)NCBICHM1_1
T2T-CHM13v2.04162,119,774 - 162,258,820 (+)NCBIT2T-CHM13v2.0
Fnip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39379,363,556 - 79,475,458 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl379,363,281 - 79,475,103 (-)EnsemblGRCm39 Ensembl
GRCm38379,455,971 - 79,568,151 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl379,455,974 - 79,567,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv37379,259,893 - 79,371,601 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera379,492,804 - 79,605,886 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map334.91NCBI
Fnip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82166,894,726 - 167,006,490 (-)NCBIGRCr8
mRatBN7.22164,596,557 - 164,708,147 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2164,598,906 - 164,707,901 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2171,817,230 - 171,926,253 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02169,833,258 - 169,942,292 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02164,442,103 - 164,551,138 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02178,223,561 - 178,334,925 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,225,915 - 178,334,900 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02197,561,442 - 197,670,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42170,865,329 - 170,975,214 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2158,695,553 - 158,804,496 (-)NCBICelera
Cytogenetic Map2q33NCBI
Fnip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547112,378,827 - 12,445,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547112,329,686 - 12,444,782 (+)NCBIChiLan1.0ChiLan1.0
FNIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23156,633,982 - 156,771,435 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14156,989,338 - 157,126,683 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04151,086,854 - 151,224,192 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14162,896,811 - 163,033,411 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4162,896,805 - 163,032,167 (+)Ensemblpanpan1.1panPan2
FNIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11555,871,782 - 55,962,676 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1555,830,806 - 55,959,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1556,192,112 - 56,324,467 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01556,573,299 - 56,706,386 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1556,573,255 - 56,702,734 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11555,853,569 - 55,944,270 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01555,911,594 - 56,043,987 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01556,225,177 - 56,357,604 (+)NCBIUU_Cfam_GSD_1.0
Fnip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530134,211,781 - 34,325,295 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365765,221,613 - 5,335,191 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365765,221,619 - 5,335,133 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl847,702,961 - 47,838,535 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1847,702,877 - 47,838,541 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2850,090,222 - 50,158,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FNIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17105,344,950 - 105,445,313 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7105,345,920 - 105,445,452 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603785,015,735 - 85,154,798 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001342   ⟹   ENSHGLP00000001300
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248483,756,247 - 3,827,288 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001343   ⟹   ENSHGLP00000001301
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248483,756,247 - 3,827,288 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001344   ⟹   ENSHGLP00000001302
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248483,756,247 - 3,808,176 (+)Ensembl
RefSeq Acc Id: XM_004868563   ⟹   XP_004868620
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,756,245 - 3,826,931 (+)NCBI
RefSeq Acc Id: XM_004868564   ⟹   XP_004868621
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,756,245 - 3,823,884 (+)NCBI
RefSeq Acc Id: XM_004868565   ⟹   XP_004868622
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,756,240 - 3,823,884 (+)NCBI
RefSeq Acc Id: XM_004868566   ⟹   XP_004868623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,756,612 - 3,823,884 (+)NCBI
RefSeq Acc Id: XM_004868567   ⟹   XP_004868624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,756,235 - 3,826,931 (+)NCBI
RefSeq Acc Id: XM_021247478   ⟹   XP_021103137
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,739,677 - 3,823,884 (+)NCBI
RefSeq Acc Id: XM_021247479   ⟹   XP_021103138
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,759,562 - 3,823,884 (+)NCBI
RefSeq Acc Id: XM_021247480   ⟹   XP_021103139
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248483,739,677 - 3,823,884 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021103137   ⟸   XM_021247478
- Peptide Label: isoform X4
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103139   ⟸   XM_021247480
- Peptide Label: isoform X7
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868624   ⟸   XM_004868567
- Peptide Label: isoform X8
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868622   ⟸   XM_004868565
- Peptide Label: isoform X3
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868620   ⟸   XM_004868563
- Peptide Label: isoform X1
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868621   ⟸   XM_004868564
- Peptide Label: isoform X2
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868623   ⟸   XM_004868566
- Peptide Label: isoform X6
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103138   ⟸   XM_021247479
- Peptide Label: isoform X5
- UniProtKB: G5AXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001300   ⟸   ENSHGLT00000001342
RefSeq Acc Id: ENSHGLP00000001301   ⟸   ENSHGLT00000001343
RefSeq Acc Id: ENSHGLP00000001302   ⟸   ENSHGLT00000001344


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001014 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001342 ENTREZGENE
  ENSHGLT00000001343 ENTREZGENE
InterPro DENN_FNIP1/2 UniProtKB/TrEMBL
  FNIP_C_dom UniProtKB/TrEMBL
  FNIP_fam UniProtKB/TrEMBL
  FNIP_mid_dom UniProtKB/TrEMBL
  FNIP_N_dom UniProtKB/TrEMBL
NCBI Gene Fnip2 ENTREZGENE
PANTHER FOLLICULIN-INTERACTING PROTEIN 2 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam FNIP_C UniProtKB/TrEMBL
  FNIP_M UniProtKB/TrEMBL
  FNIP_N UniProtKB/TrEMBL
PRINTS FOLLICULNIP1 UniProtKB/TrEMBL
PROSITE DENN_FNIP12 UniProtKB/TrEMBL
UniProt G5AXX9 ENTREZGENE, UniProtKB/TrEMBL