Lgi3 (leucine rich repeat LGI family member 3) - Rat Genome Database

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Gene: Lgi3 (leucine rich repeat LGI family member 3) Heterocephalus glaber
Analyze
Symbol: Lgi3
Name: leucine rich repeat LGI family member 3
RGD ID: 18910609
Description: INVOLVED IN regulation of exocytosis (inferred); ASSOCIATED WITH Conotruncal Cardiac Defects (ortholog); INTELLECTUAL DEVELOPMENTAL DISORDER WITH MUSCLE TONE ABNORMALITIES AND DISTAL SKELETAL DEFECTS (ortholog); FOUND IN extracellular space (ortholog); juxtaparanode region of axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat LGI family member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,726,018 - 17,737,740 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,729,290 - 17,737,677 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lgi3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,726,018 - 17,737,740 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,729,290 - 17,737,677 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LGI3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,146,830 - 22,156,806 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,146,830 - 22,157,084 (-)EnsemblGRCh38hg38GRCh38
GRCh37822,004,343 - 22,014,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,060,288 - 22,070,289 (-)NCBINCBI36Build 36hg18NCBI36
Build 34822,060,289 - 22,070,289NCBI
Celera820,966,267 - 20,976,328 (-)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,546,619 - 20,556,646 (-)NCBIHuRef
CHM1_1822,206,009 - 22,216,003 (-)NCBICHM1_1
T2T-CHM13v2.0822,420,778 - 22,430,751 (-)NCBIT2T-CHM13v2.0
Lgi3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,765,982 - 70,775,764 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,768,125 - 70,775,764 (+)EnsemblGRCm39 Ensembl
GRCm381470,528,547 - 70,538,324 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,530,685 - 70,538,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv371470,930,628 - 70,938,131 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,265,950 - 69,273,402 (+)NCBIMGSCv36mm8
Celera1468,072,371 - 68,079,876 (+)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Lgi3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81552,015,317 - 52,022,445 (+)NCBIGRCr8
mRatBN7.21545,605,611 - 45,612,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,605,611 - 45,612,739 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,723,477 - 49,730,605 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,834,982 - 50,842,110 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,694,274 - 47,701,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,220,578 - 52,227,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,220,578 - 52,227,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,944,095 - 55,951,223 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,932,145 - 50,939,273 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,948,080 - 50,955,053 (+)NCBI
Celera1545,284,005 - 45,291,134 (+)NCBICelera
Cytogenetic Map15p11NCBI
Lgi3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,634,237 - 45,644,172 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,634,237 - 45,644,172 (-)NCBIChiLan1.0ChiLan1.0
LGI3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,648,656 - 40,658,653 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,373,854 - 16,383,840 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,391,765 - 21,401,770 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,330,815 - 18,340,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,330,815 - 18,340,403 (-)Ensemblpanpan1.1panPan2
LGI3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,097,464 - 35,105,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,097,566 - 35,105,940 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,687,040 - 35,695,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,308,828 - 35,317,292 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,308,929 - 35,316,773 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,254,281 - 35,262,751 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,108,844 - 35,117,307 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,264,308 - 35,272,778 (+)NCBIUU_Cfam_GSD_1.0
Lgi3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,596,621 - 12,603,899 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,966,577 - 5,973,954 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,966,617 - 5,973,898 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGI3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,419,592 - 6,428,563 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,419,100 - 6,429,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,856,466 - 6,866,639 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LGI3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,216,373 - 20,226,744 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,216,372 - 20,225,599 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,009,472 - 22,019,709 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022564   ⟹   ENSHGLP00000022353
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475817,726,018 - 17,737,740 (-)Ensembl
RefSeq Acc Id: XM_004848279   ⟹   XP_004848336
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475817,729,290 - 17,737,677 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004848336 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022353
GenBank Protein JAN98652 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004848336   ⟸   XM_004848279
- UniProtKB: A0A0P6J2Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022353   ⟸   ENSHGLT00000022564


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015939 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022564 ENTREZGENE
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  EAR UniProtKB/TrEMBL
  EPTP UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101711898 UniProtKB/TrEMBL
NCBI Gene Lgi3 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT LGI FAMILY MEMBER 3 UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam EPTP UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE EAR UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  Putative isomerase YbhE UniProtKB/TrEMBL
UniProt A0A0P6J2Q3 ENTREZGENE, UniProtKB/TrEMBL