Elapor1 (endosome-lysosome associated apoptosis and autophagy regulator 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Elapor1 (endosome-lysosome associated apoptosis and autophagy regulator 1) Heterocephalus glaber
Analyze
Symbol: Elapor1
Name: endosome-lysosome associated apoptosis and autophagy regulator 1 (Ensembl:KIAA1324 ortholog)
RGD ID: 18908472
Description: INVOLVED IN autophagosome assembly (inferred); cellular response to starvation (inferred); positive regulation of autophagosome assembly (inferred); ASSOCIATED WITH autistic disorder (ortholog); hereditary spastic paraplegia 63 (ortholog); FOUND IN extracellular exosome (inferred); late endosome (inferred); lysosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Kiaa1324; KIAA1324 ortholog; UPF0577 protein; UPF0577 protein KIAA1324 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247724,873,468 - 4,953,655 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Elapor1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247724,873,468 - 4,953,655 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ELAPOR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381109,114,115 - 109,206,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1109,113,679 - 109,206,781 (+)EnsemblGRCh38hg38GRCh38
GRCh371109,656,737 - 109,749,403 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361109,458,056 - 109,547,377 (+)NCBINCBI36Build 36hg18NCBI36
Celera1107,925,989 - 108,018,762 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1107,549,937 - 107,642,627 (+)NCBIHuRef
CHM1_11109,771,250 - 109,864,198 (+)NCBICHM1_1
T2T-CHM13v2.01109,146,975 - 109,239,594 (+)NCBIT2T-CHM13v2.0
Elapor1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,362,995 - 108,444,064 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,363,010 - 108,443,852 (-)EnsemblGRCm39 Ensembl
GRCm383108,455,679 - 108,536,745 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,455,694 - 108,536,536 (-)EnsemblGRCm38mm10GRCm38
MGSCv373108,260,987 - 108,339,440 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,586,125 - 108,664,578 (-)NCBIMGSCv36mm8
Celera3110,792,283 - 110,871,416 (-)NCBICelera
Cytogenetic Map3F3NCBI
cM Map347.14NCBI
Elapor1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,777,323 - 198,856,497 (-)NCBIGRCr8
mRatBN7.22196,089,199 - 196,169,055 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,091,646 - 196,168,716 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02211,243,398 - 211,323,283 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,246,068 - 211,322,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,713,564 - 230,792,887 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,016,795 - 204,085,212 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12203,984,643 - 204,062,759 (-)NCBI
Celera2188,735,969 - 188,814,775 (-)NCBICelera
Cytogenetic Map2q34NCBI
Elapor1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,531,642 - 12,627,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,531,651 - 12,626,969 (+)NCBIChiLan1.0ChiLan1.0
ELAPOR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,100,092 - 118,191,353 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,260,051 - 117,351,423 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,490,488 - 111,583,703 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,654,623 - 110,744,543 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,654,844 - 110,744,323 (+)Ensemblpanpan1.1panPan2
ELAPOR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,612,130 - 42,681,161 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl642,613,546 - 42,681,015 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha645,385,697 - 45,455,848 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0642,942,285 - 43,012,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl642,942,417 - 43,013,284 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1642,673,609 - 42,743,779 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0642,631,650 - 42,701,825 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0643,067,018 - 43,137,157 (-)NCBIUU_Cfam_GSD_1.0
Elapor1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,374,997 - 19,460,830 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936704653,403 - 739,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936704653,434 - 736,660 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELAPOR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4110,881,768 - 110,953,967 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14110,881,770 - 110,954,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,375,550 - 121,448,499 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELAPOR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12024,357,584 - 24,365,702 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603833,967,182 - 33,981,820 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000009425   ⟹   ENSHGLP00000009323
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247724,873,468 - 4,953,655 (+)Ensembl
RefSeq Acc Id: XM_004853614   ⟹   XP_004853671
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_004853615   ⟹   XP_004853672
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_004853616   ⟹   XP_004853673
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_004853617   ⟹   XP_004853674
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_004853619   ⟹   XP_004853676
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,474 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_021265604   ⟹   XP_021121263
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,547 - 4,950,868 (+)NCBI
RefSeq Acc Id: XM_021265605   ⟹   XP_021121264
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247724,873,473 - 4,950,868 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004853671   ⟸   XM_004853614
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853672   ⟸   XM_004853615
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853674   ⟸   XM_004853617
- Peptide Label: isoform X5
- UniProtKB: A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853673   ⟸   XM_004853616
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121264   ⟸   XM_021265605
- Peptide Label: isoform X6
- UniProtKB: A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853676   ⟸   XM_004853619
- Peptide Label: isoform X7
RefSeq Acc Id: XP_021121263   ⟸   XM_021265604
- Peptide Label: isoform X1
- UniProtKB: G5BQV6 (UniProtKB/TrEMBL),   A0A0P6J5M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000009323   ⟸   ENSHGLT00000009425


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006684 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000009425 ENTREZGENE
Gene3D-CATH Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
InterPro EIG121-like UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Man6P_isomerase_rcpt-bd_dom_sf UniProtKB/TrEMBL
  MRH_dom UniProtKB/TrEMBL
KEGG Report hgl:101724216 UniProtKB/TrEMBL
NCBI Gene Kiaa1324 ENTREZGENE
PANTHER ENDOSOME/LYSOSOME-ASSOCIATED APOPTOSIS AND AUTOPHAGY REGULATOR 1 UniProtKB/TrEMBL
  PTHR22727 UniProtKB/TrEMBL
PROSITE MRH UniProtKB/TrEMBL
SMART Ephrin_rec_like UniProtKB/TrEMBL
Superfamily-SCOP SSF50911 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A0P6J5M4 ENTREZGENE, UniProtKB/TrEMBL
  G5BQV6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-03-10 Elapor1  endosome-lysosome associated apoptosis and autophagy regulator 1  Kiaa1324  KIAA1324 ortholog  Symbol and/or name change 5135510 APPROVED