Epn1 (epsin 1) - Rat Genome Database

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Gene: Epn1 (epsin 1) Heterocephalus glaber
Analyze
Symbol: Epn1
Name: epsin 1
RGD ID: 18903040
Description: ENCODES a protein that exhibits clathrin adaptor activity (ortholog); molecular sequestering activity (ortholog); transcription factor binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); embryonic organ development (ortholog); endocytosis (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; ASSOCIATED WITH genetic disease (ortholog); middle cerebral artery infarction (ortholog); FOUND IN cytosol (ortholog); postsynapse (ortholog); postsynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epsin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,732,571 - 1,746,888 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,732,895 - 1,746,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Epn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,732,571 - 1,746,888 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,732,895 - 1,746,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EPN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,675,226 - 55,709,533 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,675,226 - 55,709,858 (+)EnsemblGRCh38hg38GRCh38
GRCh371956,186,592 - 56,220,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,878,404 - 60,898,945 (+)NCBINCBI36Build 36hg18NCBI36
Build 341960,878,403 - 60,898,944NCBI
Celera1953,228,855 - 53,249,427 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,497,593 - 52,517,630 (+)NCBIHuRef
CHM1_11956,180,226 - 56,200,825 (+)NCBICHM1_1
T2T-CHM13v2.01958,772,202 - 58,806,505 (+)NCBIT2T-CHM13v2.0
Epn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3975,083,207 - 5,101,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl75,083,234 - 5,101,177 (+)EnsemblGRCm39 Ensembl
GRCm3875,080,137 - 5,098,179 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl75,080,235 - 5,098,178 (+)EnsemblGRCm38mm10GRCm38
MGSCv3775,031,907 - 5,049,778 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,683,392 - 4,701,263 (+)NCBIMGSCv36mm8
Celera74,822,389 - 4,840,262 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.94NCBI
Epn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8177,771,335 - 77,789,411 (-)NCBIGRCr8
mRatBN7.2168,742,491 - 68,760,570 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,742,789 - 68,758,874 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,087,576 - 74,105,651 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,651,885 - 82,669,960 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0175,800,539 - 75,818,619 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,294,153 - 72,310,217 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,294,153 - 72,311,856 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0176,226,173 - 76,242,237 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,479,998 - 67,496,066 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,558,113 - 67,574,177 (-)NCBI
Celera168,360,140 - 68,376,208 (+)NCBICelera
Cytogenetic Map1q12NCBI
Epn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567669,685 - 682,852 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955567669,333 - 683,283 (-)NCBIChiLan1.0ChiLan1.0
EPN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,816,561 - 61,837,862 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,546,588 - 63,567,706 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,722,107 - 52,743,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,408,678 - 61,428,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,408,695 - 61,427,647 (+)Ensemblpanpan1.1panPan2
EPN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,059,022 - 102,073,665 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,059,181 - 102,073,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,116,113 - 102,130,802 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01102,712,494 - 102,727,183 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,712,496 - 102,727,223 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,350,090 - 102,364,779 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,061,977 - 102,076,667 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01102,825,037 - 102,839,725 (-)NCBIUU_Cfam_GSD_1.0
Epn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,684,602 - 1,703,390 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936981194,157 - 213,066 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936981194,176 - 213,021 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,789,946 - 59,802,299 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,789,952 - 59,802,302 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,762,216 - 54,768,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1648,265,498 - 48,287,817 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl648,267,365 - 48,288,296 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045922,638 - 944,920 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006921   ⟹   ENSHGLP00000006837
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248321,732,571 - 1,746,888 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000006922   ⟹   ENSHGLP00000006838
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248321,732,571 - 1,743,917 (-)Ensembl
RefSeq Acc Id: XM_004866612   ⟹   XP_004866669
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,934 (-)NCBI
RefSeq Acc Id: XM_004866614   ⟹   XP_004866671
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,934 (-)NCBI
RefSeq Acc Id: XM_013066395   ⟹   XP_012921849
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,934 (-)NCBI
RefSeq Acc Id: XM_013066396   ⟹   XP_012921850
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,934 (-)NCBI
RefSeq Acc Id: XM_021245942   ⟹   XP_021101601
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,963 (-)NCBI
RefSeq Acc Id: XM_021245943   ⟹   XP_021101602
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248321,732,895 - 1,746,963 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021101602   ⟸   XM_021245943
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021101601   ⟸   XM_021245942
- Peptide Label: isoform X1
RefSeq Acc Id: XP_012921850   ⟸   XM_013066396
- Peptide Label: isoform X4
RefSeq Acc Id: XP_004866671   ⟸   XM_004866614
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004866669   ⟸   XM_004866612
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JYG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012921849   ⟸   XM_013066395
- Peptide Label: isoform X1
RefSeq Acc Id: ENSHGLP00000006838   ⟸   ENSHGLT00000006922
RefSeq Acc Id: ENSHGLP00000006837   ⟸   ENSHGLT00000006921


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004989 Ensembl, ENTREZGENE
  ENSHGLG00100051774 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006921 ENTREZGENE
  ENSHGLT00100044074 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.90 UniProtKB/TrEMBL
InterPro ENTH UniProtKB/TrEMBL
  ENTH_VHS UniProtKB/TrEMBL
  UIM_dom UniProtKB/TrEMBL
KEGG Report hgl:101723807 UniProtKB/TrEMBL
NCBI Gene Epn1 ENTREZGENE
PANTHER EPSIN-1 UniProtKB/TrEMBL
  EPSIN/ENT-RELATED UniProtKB/TrEMBL
Pfam ENTH UniProtKB/TrEMBL
PROSITE ENTH UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
SMART ENTH UniProtKB/TrEMBL
  UIM UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/TrEMBL
UniProt A0A0P6JYG9 ENTREZGENE, UniProtKB/TrEMBL