Poll (DNA polymerase lambda) - Rat Genome Database

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Gene: Poll (DNA polymerase lambda) Heterocephalus glaber
Analyze
Symbol: Poll
Name: DNA polymerase lambda
RGD ID: 18902965
Description: ENCODES a protein that exhibits 5'-deoxyribose-5-phosphate lyase activity (inferred); DNA binding (inferred); DNA-directed DNA polymerase activity (inferred); INVOLVED IN base-excision repair, gap-filling (inferred); DNA biosynthetic process (inferred); DNA metabolic process (inferred); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH split hand-foot malformation (ortholog); FOUND IN site of double-strand break (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248311,076,758 - 1,087,191 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248311,077,469 - 1,087,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Poll
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248311,076,758 - 1,087,191 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248311,077,469 - 1,087,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
POLL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810101,578,882 - 101,588,270 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10101,578,882 - 101,588,270 (-)EnsemblGRCh38hg38GRCh38
GRCh3710103,338,639 - 103,348,027 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610103,328,629 - 103,337,963 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410103,328,628 - 103,337,963NCBI
Celera1097,077,425 - 97,086,813 (-)NCBICelera
Cytogenetic Map10q24.32NCBI
HuRef1096,969,236 - 96,978,624 (-)NCBIHuRef
CHM1_110103,622,300 - 103,631,683 (-)NCBICHM1_1
T2T-CHM13v2.010102,462,924 - 102,472,307 (-)NCBIT2T-CHM13v2.0
Poll
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391945,540,714 - 45,549,025 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1945,540,714 - 45,548,970 (-)EnsemblGRCm39 Ensembl
GRCm381945,552,275 - 45,560,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1945,552,275 - 45,560,531 (-)EnsemblGRCm38mm10GRCm38
MGSCv371945,626,765 - 45,635,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361945,605,586 - 45,613,854 (-)NCBIMGSCv36mm8
Celera1946,319,899 - 46,328,193 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.75NCBI
Poll
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81254,349,229 - 254,357,689 (-)NCBIGRCr8
mRatBN7.21244,400,202 - 244,408,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1244,400,204 - 244,408,662 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1252,541,994 - 252,550,357 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01259,245,211 - 259,253,568 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01251,891,640 - 251,899,943 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01265,290,337 - 265,298,847 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1265,290,339 - 265,298,797 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01272,729,883 - 272,738,410 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41250,718,414 - 250,726,874 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11250,980,066 - 250,984,727 (-)NCBI
Celera1240,209,010 - 240,217,470 (-)NCBICelera
Cytogenetic Map1q54NCBI
Poll
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554858,691,453 - 8,703,872 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554858,691,886 - 8,700,681 (+)NCBIChiLan1.0ChiLan1.0
POLL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28113,464,736 - 113,474,145 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110113,470,055 - 113,479,464 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01098,181,049 - 98,190,463 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110101,653,978 - 101,663,378 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10101,653,978 - 101,663,360 (-)Ensemblpanpan1.1panPan2
POLL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12814,193,065 - 14,201,312 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2814,193,067 - 14,201,334 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2814,361,791 - 14,370,086 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02814,661,232 - 14,669,527 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2814,661,247 - 14,668,573 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12814,205,964 - 14,214,268 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02814,247,498 - 14,255,789 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02814,379,611 - 14,387,906 (-)NCBIUU_Cfam_GSD_1.0
Poll
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721332,581,751 - 32,591,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366004,185,046 - 4,194,618 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366004,184,979 - 4,194,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14112,606,196 - 112,617,319 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114112,608,558 - 112,617,348 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214122,351,914 - 122,360,713 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1994,602,738 - 94,612,393 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl994,601,992 - 94,611,492 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604855,678,737 - 55,688,427 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027665   ⟹   ENSHGLP00000027423
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,076,758 - 1,087,191 (-)Ensembl
RefSeq Acc Id: XM_004866347   ⟹   XP_004866404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,202 (-)NCBI
RefSeq Acc Id: XM_004866348   ⟹   XP_004866405
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,202 (-)NCBI
RefSeq Acc Id: XM_004866350   ⟹   XP_004866407
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,340 (-)NCBI
RefSeq Acc Id: XM_013066108   ⟹   XP_012921562
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,086,377 (-)NCBI
RefSeq Acc Id: XM_021245590   ⟹   XP_021101249
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,202 (-)NCBI
RefSeq Acc Id: XM_021245591   ⟹   XP_021101250
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,202 (-)NCBI
RefSeq Acc Id: XM_021245592   ⟹   XP_021101251
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,077,469 - 1,087,340 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021101251   ⟸   XM_021245592
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866407   ⟸   XM_004866350
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101250   ⟸   XM_021245591
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866405   ⟸   XM_004866348
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866404   ⟸   XM_004866347
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101249   ⟸   XM_021245590
- Peptide Label: isoform X1
- UniProtKB: G5CAF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012921562   ⟸   XM_013066108
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000027423   ⟸   ENSHGLT00000027665


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019504 Ensembl, ENTREZGENE
  ENSHGLG00100014331 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027665 ENTREZGENE
  ENSHGLT00100019648 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.110 UniProtKB/TrEMBL
  3.30.210.10 UniProtKB/TrEMBL
  3.30.460.10 UniProtKB/TrEMBL
  3.40.50.10190 UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
InterPro BRCT_dom UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  DNA-dir_DNA_pol_X UniProtKB/TrEMBL
  DNA_pol-X_BS UniProtKB/TrEMBL
  DNA_pol_b-like_N UniProtKB/TrEMBL
  DNA_pol_B_palm_palm UniProtKB/TrEMBL
  DNA_pol_lambd_fingers_domain UniProtKB/TrEMBL
  DNA_pol_lamdba_lyase_dom_sf UniProtKB/TrEMBL
  DNA_Pol_thumb_sf UniProtKB/TrEMBL
  DNA_pol_X UniProtKB/TrEMBL
  DNA_pol_X_beta-like UniProtKB/TrEMBL
  NT_sf UniProtKB/TrEMBL
  PolB_thumb UniProtKB/TrEMBL
KEGG Report hgl:101696600 UniProtKB/TrEMBL
NCBI Gene Poll ENTREZGENE
PANTHER DNA POLYMERASE LAMBDA UniProtKB/TrEMBL
  PTHR11276 UniProtKB/TrEMBL
Pfam DNA_pol_B_palm UniProtKB/TrEMBL
  DNA_pol_B_thumb UniProtKB/TrEMBL
  DNA_pol_lambd_f UniProtKB/TrEMBL
  HHH_8 UniProtKB/TrEMBL
PRINTS DNAPOLX UniProtKB/TrEMBL
  DNAPOLXBETA UniProtKB/TrEMBL
PROSITE BRCT UniProtKB/TrEMBL
  DNA_POLYMERASE_X UniProtKB/TrEMBL
SMART POLXc UniProtKB/TrEMBL
Superfamily-SCOP PsbU/PolX domain-like UniProtKB/TrEMBL
  SSF47802 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
  SSF81301 UniProtKB/TrEMBL
UniProt G5CAF7 ENTREZGENE, UniProtKB/TrEMBL