Klk6 (kallikrein related peptidase 6) - Rat Genome Database

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Gene: Klk6 (kallikrein related peptidase 6) Heterocephalus glaber
Analyze
Symbol: Klk6
Name: kallikrein related peptidase 6
RGD ID: 18901723
Description: ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN positive regulation of G protein-coupled receptor signaling pathway (ortholog); regulation of neuron projection development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); breast carcinoma (ortholog); demyelinating disease (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kallikrein-6; kallikrein-6 isoform A preproprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,785,644 - 3,793,074 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,785,727 - 3,793,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Klk6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,785,644 - 3,793,074 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,785,727 - 3,793,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KLK6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381950,958,631 - 50,969,591 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1950,958,631 - 50,969,673 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,461,887 - 51,472,847 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,153,699 - 56,164,741 (-)NCBINCBI36Build 36hg18NCBI36
Build 341956,153,699 - 56,164,741NCBI
Celera1948,512,220 - 48,523,480 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1947,794,177 - 47,805,721 (-)NCBIHuRef
CHM1_11951,463,632 - 51,474,713 (-)NCBICHM1_1
T2T-CHM13v2.01954,046,713 - 54,057,995 (-)NCBIT2T-CHM13v2.0
Klk6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,473,967 - 43,481,219 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,473,923 - 43,481,454 (+)EnsemblGRCm39 Ensembl
GRCm38743,824,438 - 43,832,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,824,499 - 43,832,030 (+)EnsemblGRCm38mm10GRCm38
MGSCv37751,079,914 - 51,087,397 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,693,492 - 43,699,828 (+)NCBIMGSCv36mm8
Celera739,293,226 - 39,300,707 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.28NCBI
Klk6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81103,415,411 - 103,422,682 (+)NCBIGRCr8
mRatBN7.2194,278,863 - 94,286,136 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl194,280,340 - 94,286,121 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,664,377 - 99,671,533 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01108,137,048 - 108,144,202 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01101,426,648 - 101,433,802 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,762,195 - 99,769,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,762,253 - 99,769,488 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,830,974 - 100,838,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,254,350 - 94,261,500 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1194,332,460 - 94,339,610 (+)NCBI
Celera188,546,437 - 88,553,549 (+)NCBICelera
Cytogenetic Map1q22NCBI
Klk6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555581,502,881 - 1,509,558 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555581,501,806 - 1,509,461 (+)NCBIChiLan1.0ChiLan1.0
KLK6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,028,080 - 57,039,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11958,948,642 - 58,959,921 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01947,925,017 - 47,936,314 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,815,073 - 56,826,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,815,073 - 56,826,689 (-)Ensemblpanpan1.1panPan2
KLK6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,902,147 - 105,907,585 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,474,567 - 105,482,203 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,409,595 - 106,419,174 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,406,669 - 106,433,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,082,387 - 106,090,003 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,723,801 - 105,731,455 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,519,343 - 106,526,983 (+)NCBIUU_Cfam_GSD_1.0
Klk6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,745,642 - 22,753,731 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936889621,630 - 629,678 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936889621,645 - 628,454 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLK6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,629,991 - 55,638,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,629,983 - 55,639,215 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KLK6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,980,680 - 43,991,873 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,980,701 - 43,990,060 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607324,005,498 - 24,016,398 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021252   ⟹   ENSHGLP00000021049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248323,785,644 - 3,793,074 (+)Ensembl
RefSeq Acc Id: XM_004866780   ⟹   XP_004866837
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248323,785,727 - 3,793,078 (+)NCBI
RefSeq Acc Id: XM_004866781   ⟹   XP_004866838
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248323,785,822 - 3,793,078 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004866837 (Get FASTA)   NCBI Sequence Viewer  
  XP_004866838 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021049
GenBank Protein JAN97350 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004866837   ⟸   XM_004866780
- UniProtKB: A0A0P6K1U5 (UniProtKB/TrEMBL),   G5BRA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866838   ⟸   XM_004866781
- UniProtKB: A0A0P6K1U5 (UniProtKB/TrEMBL),   G5BRA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021049   ⟸   ENSHGLT00000021252


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015037 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021252 ENTREZGENE
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene Klk6 ENTREZGENE
PANTHER RIKEN CDNA 2210010C04 GENE UniProtKB/TrEMBL
  TRYPSIN-RELATED UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A0P6K1U5 ENTREZGENE, UniProtKB/TrEMBL
  G5BRA1 ENTREZGENE, UniProtKB/TrEMBL