Pip4k2b (phosphatidylinositol-5-phosphate 4-kinase type 2 beta) - Rat Genome Database

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Gene: Pip4k2b (phosphatidylinositol-5-phosphate 4-kinase type 2 beta) Heterocephalus glaber
Analyze
Symbol: Pip4k2b
Name: phosphatidylinositol-5-phosphate 4-kinase type 2 beta
RGD ID: 18900989
Description: ENCODES a protein that exhibits GTP binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (ortholog); autophagosome-lysosome fusion (ortholog); negative regulation of insulin receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN autophagosome (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 5-phosphate 4-kinase type-2 beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,908,037 - 3,931,430 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,907,891 - 3,931,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Pip4k2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,908,037 - 3,931,430 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,907,891 - 3,931,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PIP4K2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381738,765,691 - 38,799,556 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1738,765,691 - 38,800,126 (-)EnsemblGRCh38hg38GRCh38
GRCh371736,921,944 - 36,955,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361734,175,470 - 34,209,684 (-)NCBINCBI36Build 36hg18NCBI36
Build 341734,185,753 - 34,209,684NCBI
Celera1733,582,904 - 33,617,123 (-)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1732,718,046 - 32,752,229 (-)NCBIHuRef
CHM1_11737,157,249 - 37,191,464 (-)NCBICHM1_1
T2T-CHM13v2.01739,628,767 - 39,662,641 (-)NCBIT2T-CHM13v2.0
Pip4k2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,605,983 - 97,635,530 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,605,983 - 97,635,530 (-)EnsemblGRCm39 Ensembl
GRCm381197,715,157 - 97,744,704 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,715,157 - 97,744,704 (-)EnsemblGRCm38mm10GRCm38
MGSCv371197,576,471 - 97,606,018 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361197,531,247 - 97,560,794 (-)NCBIMGSCv36mm8
Celera11107,364,951 - 107,394,395 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.07NCBI
Pip4k2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81083,202,379 - 83,231,292 (-)NCBIGRCr8
mRatBN7.21082,706,016 - 82,734,938 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1082,701,098 - 82,734,938 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1087,657,124 - 87,683,171 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01087,155,212 - 87,181,257 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01082,547,794 - 82,573,836 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01085,655,223 - 85,684,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,658,324 - 85,684,138 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01085,446,054 - 85,475,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,464,211 - 86,490,407 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11086,478,580 - 86,504,777 (-)NCBI
Celera1081,464,717 - 81,490,530 (-)NCBICelera
Cytogenetic Map10q31NCBI
Pip4k2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,842,814 - 13,856,302 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,842,814 - 13,856,301 (-)NCBIChiLan1.0ChiLan1.0
PIP4K2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21926,148,856 - 26,184,829 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11728,032,553 - 28,068,404 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01718,471,609 - 18,507,916 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11718,746,712 - 18,782,296 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1718,746,712 - 18,782,296 (+)Ensemblpanpan1.1panPan2
PIP4K2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1923,445,350 - 23,473,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl923,445,482 - 23,470,184 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha922,917,339 - 22,945,157 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0924,240,711 - 24,268,753 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl924,240,678 - 24,268,751 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,012,697 - 23,040,506 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0923,273,776 - 23,301,583 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0923,399,552 - 23,427,598 (+)NCBIUU_Cfam_GSD_1.0
Pip4k2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560222,873,427 - 22,906,188 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649014,168,981 - 14,202,108 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649014,168,951 - 14,201,712 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP4K2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,317,208 - 23,346,424 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,317,113 - 23,345,661 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PIP4K2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11667,391,786 - 67,429,560 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1667,406,981 - 67,427,691 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607738,388,868 - 38,426,938 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020527   ⟹   ENSHGLP00000020325
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247953,908,037 - 3,931,430 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000020528   ⟹   ENSHGLP00000020326
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247953,908,059 - 3,928,030 (+)Ensembl
RefSeq Acc Id: XM_004859533   ⟹   XP_004859590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247953,907,895 - 3,931,246 (+)NCBI
RefSeq Acc Id: XM_021239907   ⟹   XP_021095566
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247953,907,891 - 3,931,246 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004859590 (Get FASTA)   NCBI Sequence Viewer  
  XP_021095566 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020325
  ENSHGLP00100016983
GenBank Protein JAN98828 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021095566   ⟸   XM_021239907
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004859590   ⟸   XM_004859533
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J862 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020326   ⟸   ENSHGLT00000020528
RefSeq Acc Id: ENSHGLP00000020325   ⟸   ENSHGLT00000020527


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014540 Ensembl, ENTREZGENE
  ENSHGLG00100012526 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020527 ENTREZGENE
  ENSHGLT00100017165 UniProtKB/TrEMBL
Gene3D-CATH 2-Layer Sandwich UniProtKB/TrEMBL
  3.30.800.10 UniProtKB/TrEMBL
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/TrEMBL
  PInositol-4-P-5-kinase UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_core UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_N UniProtKB/TrEMBL
KEGG Report hgl:101719792 UniProtKB/TrEMBL
NCBI Gene Pip4k2b ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA UniProtKB/TrEMBL
  PTHR23086 UniProtKB/TrEMBL
Pfam PIP5K UniProtKB/TrEMBL
PROSITE PIPK UniProtKB/TrEMBL
SMART PIPKc UniProtKB/TrEMBL
Superfamily-SCOP SAICAR synthase-like UniProtKB/TrEMBL
UniProt A0A0P6J862 ENTREZGENE, UniProtKB/TrEMBL