HASPIN (histone H3 associated protein kinase) - Rat Genome Database

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Gene: HASPIN (histone H3 associated protein kinase) Chlorocebus sabaeus
Analyze
Symbol: HASPIN
Name: histone H3 associated protein kinase
RGD ID: 18794296
Description: ENCODES a protein that exhibits DNA binding (ortholog); INVOLVED IN chromosome organization involved in meiotic cell cycle (ortholog); gene expression (ortholog); homologous chromosome segregation (ortholog); ASSOCIATED WITH Canavan disease (ortholog); FOUND IN male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: germ cell associated 2, haspin; GSG2; serine/threonine-protein kinase haspin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,226,292 - 3,229,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,226,582 - 3,228,978 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,567,036 - 18,569,871 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HASPIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,226,292 - 3,229,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,226,582 - 3,228,978 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,567,036 - 18,569,871 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
HASPIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,723,903 - 3,726,699 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,723,903 - 3,726,699 (+)EnsemblGRCh38hg38GRCh38
GRCh37173,627,197 - 3,629,993 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,573,946 - 3,576,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 34173,573,945 - 3,576,742NCBI
Celera173,638,895 - 3,641,691 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,517,398 - 3,520,194 (+)NCBIHuRef
CHM1_1173,636,500 - 3,639,296 (+)NCBICHM1_1
T2T-CHM13v2.0173,612,491 - 3,615,287 (+)NCBIT2T-CHM13v2.0
Haspin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,026,310 - 73,029,120 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,026,311 - 73,029,120 (-)EnsemblGRCm39 Ensembl
GRCm381173,135,484 - 73,138,294 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,135,485 - 73,138,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,948,986 - 72,951,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,951,680 - 72,954,489 (-)NCBIMGSCv36mm8
Celera1180,669,945 - 80,672,755 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.25NCBI
Haspin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,246,244 - 58,249,031 (-)NCBIGRCr8
mRatBN7.21057,747,731 - 57,750,518 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,747,573 - 57,750,512 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,409,392 - 62,412,179 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,897,871 - 61,900,658 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,396,993 - 57,399,780 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,695,403 - 59,698,398 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,695,913 - 59,698,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,434,870 - 59,437,669 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1056,871,875 - 56,874,870 (-)NCBICelera
Cytogenetic Map10q24NCBI
Haspin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,078,346 - 13,104,241 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,099,958 - 13,104,337 (-)NCBIChiLan1.0ChiLan1.0
HASPIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21911,334,287 - 11,337,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11713,299,919 - 13,304,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,772,899 - 3,775,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,767,364 - 3,770,167 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,767,404 - 3,769,800 (+)Ensemblpanpan1.1panPan2
HASPIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,540,417 - 47,542,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl947,540,446 - 47,542,791 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,702,456 - 46,707,252 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,385,533 - 48,390,326 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,385,551 - 48,387,896 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,163,195 - 47,167,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,452,429 - 47,457,225 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,508,307 - 47,513,105 (+)NCBIUU_Cfam_GSD_1.0
Haspin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,496,630 - 55,499,613 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677401,395 - 403,713 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677401,198 - 404,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HASPIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,820,526 - 49,822,873 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,820,435 - 49,823,515 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Haspin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,371,874 - 6,374,195 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,371,639 - 6,374,517 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 5 18 16
Below cutoff 31 2 44

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008009878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000017964   ⟹   ENSCSAP00000017434
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl163,226,582 - 3,228,978 (+)Ensembl
RefSeq Acc Id: XM_008009878   ⟹   XP_008008069
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1163,226,292 - 3,229,349 (+)NCBI
Vero_WHO_p1.0NW_02366605918,567,036 - 18,569,871 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008008069 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000017434.1
Reference Protein Sequences
RefSeq Acc Id: XP_008008069   ⟸   XM_008009878
- UniProtKB: A0A0D9S995 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000017434   ⟸   ENSCSAT00000017964


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000000571 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017964.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro GSG2_C UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
KEGG Report csab:103242165 UniProtKB/TrEMBL
NCBI Gene HASPIN ENTREZGENE
PANTHER INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE HASPIN UniProtKB/TrEMBL
Pfam Haspin_kinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART DUF3635 UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9S995 ENTREZGENE, UniProtKB/TrEMBL