LYPD5 (LY6/PLAUR domain containing 5)

Gene: LYPD5 (LY6/PLAUR domain containing 5) Chlorocebus sabaeus

Analyze

Symbol:

LYPD5

Name:

LY6/PLAUR domain containing 5

RGD ID:

18793665

Description:

ASSOCIATED WITH ethylmalonic encephalopathy (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); side of membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ly6/PLAUR domain-containing protein 5

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	37,308,038 - 37,349,342 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	37,324,610 - 37,329,872 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	16,868,456 - 16,878,784 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ethylmalonic encephalopathy (ISO)

genetic disease (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

plasma membrane (IEA)

side of membrane (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LYPD5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	37,308,038 - 37,349,342 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	37,324,610 - 37,329,872 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	16,868,456 - 16,878,784 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LYPD5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	43,795,927 - 43,820,634 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	43,785,874 - 43,827,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	44,300,079 - 44,324,786 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	48,992,233 - 49,016,626 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	41,103,571 - 41,128,348 (-)	NCBI		Celera
Cytogenetic Map	19	q13.31	NCBI
HuRef	19	40,732,224 - 40,757,129 (-)	NCBI		HuRef
CHM1_1	19	44,302,074 - 44,326,758 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	46,618,728 - 46,643,530 (-)	NCBI		T2T-CHM13v2.0

Lypd5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	24,048,621 - 24,053,672 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	24,048,621 - 24,054,534 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	24,349,196 - 24,354,247 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	24,349,196 - 24,355,109 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	25,134,243 - 25,138,852 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	24,057,956 - 24,063,009 (+)	NCBI		MGSCv36	mm8
Celera	7	18,972,963 - 18,975,272 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	10.27	NCBI

Lypd5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	89,057,719 - 89,069,696 (+)	NCBI		GRCr8
mRatBN7.2	1	79,929,818 - 79,941,791 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,935,240 - 79,941,039 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	85,328,923 - 85,333,997 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	93,878,823 - 93,883,880 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	87,084,735 - 87,089,809 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	81,202,832 - 81,213,928 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	81,208,212 - 81,213,937 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	82,466,406 - 82,477,023 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	79,591,516 - 79,596,573 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	74,389,415 - 74,394,472 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Lypd5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	1,519,391 - 1,523,708 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955555	1,519,388 - 1,523,075 (-)	NCBI	ChiLan1.0	ChiLan1.0

LYPD5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	49,959,591 - 49,990,388 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	51,819,269 - 51,862,722 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	40,735,046 - 40,776,386 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	49,349,880 - 49,380,252 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	49,349,880 - 49,380,252 (-)	Ensembl	panpan1.1		panPan2

LYPD5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	111,369,124 - 111,381,476 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	111,378,091 - 111,381,480 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	110,849,270 - 110,862,243 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	111,942,522 - 111,955,526 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	111,951,349 - 111,955,525 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	111,576,814 - 111,580,975 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	111,202,520 - 111,214,794 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	112,085,652 - 112,098,626 (+)	NCBI		UU_Cfam_GSD_1.0

Lypd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	16,615,581 - 16,642,149 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936706	962,993 - 989,315 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LYPD5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	50,608,075 - 50,612,396 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	50,607,723 - 50,612,376 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	46,468,646 - 46,470,740 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Lypd5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	1,289,790 - 1,292,803 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624907	1,289,272 - 1,292,873 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	16	12	36
Below cutoff	20	5	24

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007997055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007997060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000001383 ⟹ ENSCSAP00000014695

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	37,324,610 - 37,329,872 (-)	Ensembl

RefSeq Acc Id:

XM_007997058 ⟹ XP_007995249

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	37,324,149 - 37,335,077 (-)	NCBI
Vero_WHO_p1.0	NW_023666073	16,868,456 - 16,878,784 (-)	NCBI

Sequence:

show sequence

TCTGCCTCCCAGGAGAGCCCAGCCTGCAACAACACAGGGTCCCAAGGCCTACAGTGCTACAGTT
TTGAGCACACCTACTTTGGCCCATTTGACCTCAGGGCCATGAAGCTGCCCAGCATCTCCTGTCC
TCACGAGTGTTTTGAGGCTATCCTGTCTCTGGACACCGGGTATCGCGCGCCGGTGACCCTGGTG
CGGAAGGGCTGCTGGACCGGGCCGCCTGCCGGCCAGACGCAATCGAACCCCGACGCGCTACCGC
CAGACTACTCGGTGGTGCGCGGCTGCACAACTGATAAGTGCAACGCCCACCTCATGACTCATGA
CGCCCTCCCCAACCTGAGCCAAGCACCCGAACCACCGACGCTCAGCGGCGCCGAGTGCTACGCC
TGTATTGGGGTCCATCAGGATGACTGCGCTATCAGCAAGTCCCGTAGGGTCCAGTGTCACCAGG
ACCAGACCGCCTGCTTCCAGGGCAATGGCAGAATGACAGTCGGCAATTTCTCAGTCCCTGTGTA
CATCAGAACCTGCCACCGGCCCTCCTGCACCACTGAGGGCACCACCAGCCCCTGGACAGCCATC
GACCTCCAGGGCTCCTGCTGTGAGGGGCACCTCTGCAACAGGAAATCCATGATCCAGCCCTTCA
ACAGTGCTTTGGCCACCACCTCTCCCCGAGCAGTACAGGTCCTGGCCCTGCTCCTCCCGGTCCT
CCTGCTGGTGGGGCTCTCATAGACTGCCCCTCCAGGATGCTGGGGACAGGGTTCACATACCTCC
TTCTTGCTGCTTCAGCCCCTATCACATAGCTCACTGGAAAATGATGTTAAAATAAGAATTACAC
TCGTGTCCCTCTGGCCTTTCATCTCTCCCTCCCTCGTGCCCCCCAACCTGGTCAACAGGACTGG
AACAAACTGGACACAGTCACCAGCATCCCAGGGGAGGGCAAAACAGCCATGTCCTGCCCTGATG
AAGAGCAATTCTCATCACAGCTGTTACTTACTGAGCACCAGGCACCCCGTAACACGGCTTCCTG
TGCTCTCCCTCCAGAGCTTGTCGCAGCTCTAGGAGGGAGCTATACAATGATGTCTTTATTAGTG
TCATCATGAGAGGCCCAATAAGCAGTATGCCCTCACAGTTAGTAGGCCAGCCTCTGGAGGTAAG
CTGCATGGGTTCAAATCCCAGCTCCACCGTTCATC

hide sequence

RefSeq Acc Id:

XM_007997060 ⟹ XP_007995251

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	37,324,149 - 37,330,361 (-)	NCBI
Vero_WHO_p1.0	NW_023666073	16,868,456 - 16,873,759 (-)	NCBI

Sequence:

show sequence

GAGGTGTTGGAGGCTGAGGATGTGTGGATGAGTGGGGAGATGGGGGTCAGAGAAGTCTTAGAGG
AGGGGACGATGAATGTATCTTTGGGTATGGAGAAGTGGCCCCAGGATTGGAAGCTGTGTGGGTG
GTGTGTGTTGGGGTAGGGTGAGGGAAGGAAAGTCAAAAGGCCATATATGCCACCCTCAGATTAG
AGCAGGGTGTTGGGAGGGGTGTAGGAAGAAGGCCAGCAAGACACCAATCATTCAAAATTAAGGG
TTCCAGACTTCTAGTTCCCTCCTCCCTCAGACCCAGAAGTGCAGGCCTCCAGCAACTGAGGATC
ACCCTGGTTCCATCACGATTACCTAGGAAGAGACCCGCCCACATAGGGAGGGTGGGACGGAGAA
ATACTGGCCAGGCAGGGTGGCCGGGATGCTTAGGACTCAGTAGGGAGAACCAGCCAGGCAGCAC
ATCACAGCGGGAGGAGCTGTCCCAGGTGGCGCAGCTCAGCAATGGCAATGGGGGTCCCCAGAGT
CATTCTCCTCTGCCTCTTTGGGGCTGCACTCTGCCTGACAGGGTCCCAAGGCCTACAGTGCTAC
AGTTTTGAGCACACCTACTTTGGCCCATTTGACCTCAGGGCCATGAAGCTGCCCAGCATCTCCT
GTCCTCACGAGTGTTTTGAGGCTATCCTGTCTCTGGACACCGGGTATCGCGCGCCGGTGACCCT
GGTGCGGAAGGGCTGCTGGACCGGGCCGCCTGCCGGCCAGACGCAATCGAACCCCGACGCGCTA
CCGCCAGACTACTCGGTGGTGCGCGGCTGCACAACTGATAAGTGCAACGCCCACCTCATGACTC
ATGACGCCCTCCCCAACCTGAGCCAAGCACCCGAACCACCGACGCTCAGCGGCGCCGAGTGCTA
CGCCTGTATTGGGGTCCATCAGGATGACTGCGCTATCAGCAAGTCCCGTAGGGTCCAGTGTCAC
CAGGACCAGACCGCCTGCTTCCAGGGCAATGGCAGAATGACAGTCGGCAATTTCTCAGTCCCTG
TGTACATCAGAACCTGCCACCGGCCCTCCTGCACCACTGAGGGCACCACCAGCCCCTGGACAGC
CATCGACCTCCAGGGCTCCTGCTGTGAGGGGCACCTCTGCAACAGGAAATCCATGATCCAGCCC
TTCAACAGTGCTTTGGCCACCACCTCTCCCCGAGCAGTACAGGTCCTGGCCCTGCTCCTCCCGG
TCCTCCTGCTGGTGGGGCTCTCATAGACTGCCCCTCCAGGATGCTGGGGACAGGGTTCACATAC
CTCCTTCTTGCTGCTTCAGCCCCTATCACATAGCTCACTGGAAAATGATGTTAAAATAAGAATT
ACACTCGTGTCCCTCTGGCCTTTCATCTCTCCCTCCCTCGTGCCCCCCAACCTGGTCAACAGGA
CTGGAACAAACTGGACACAGTCACCAGCATCCCAGGGGAGGGCAAAACAGCCATGTCCTGCCCT
GATGAAGAGCAATTCTCATCACAGCTGTTACTTACTGAGCACCAGGCACCCCGTAACACGGCTT
CCTGTGCTCTCCCTCCAGAGCTTGTCGCAGCTCTAGGAGGGAGCTATACAATGATGTCTTTATT
AGTGTCATCATGAGAGGCCCAATAAGCAGTATGCCCTCACAGTTAGTAGGCCAGCCTCTGGAGG
TAAGCTGCATGGGTTCAAATCCCAGCTCCACCGTTCATC

hide sequence

Protein Sequences


Protein RefSeqs	XP_007995249	(Get FASTA)	NCBI Sequence Viewer
	XP_007995251	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000014695
	ENSCSAP00000014695.1

RefSeq Acc Id:	XP_007995249 ⟸ XM_007997058
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_007995251 ⟸ XM_007997060
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9S1F6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000014695 ⟸ ENSCSAT00000001383

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000003357	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000001383.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.60.10	UniProtKB/TrEMBL
InterPro	CD59_antigen_CS	UniProtKB/TrEMBL
	LY6_UPA_recep-like	UniProtKB/TrEMBL
	Snake_toxin-like_sf	UniProtKB/TrEMBL
NCBI Gene	LYPD5	ENTREZGENE
PANTHER	LY6/PLAUR DOMAIN-CONTAINING PROTEIN 5	UniProtKB/TrEMBL
	UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR-RELATED	UniProtKB/TrEMBL
Pfam	UPAR_LY6	UniProtKB/TrEMBL
PROSITE	LY6_UPAR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57302	UniProtKB/TrEMBL
UniProt	A0A0D9S1F6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar