LPAR3 (lysophosphatidic acid receptor 3)

Gene: LPAR3 (lysophosphatidic acid receptor 3) Chlorocebus sabaeus

Analyze

Symbol:

LPAR3

Name:

lysophosphatidic acid receptor 3

RGD ID:

18770218

Description:

ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); phospholipid binding (ortholog); INVOLVED IN bleb assembly (ortholog); collateral sprouting (ortholog); G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; FOUND IN axon (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	48,457,903 - 48,538,754 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	48,485,708 - 48,540,513 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	69,229,208 - 69,311,934 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IEA)

bleb assembly (ISO)

collateral sprouting (ISO)

G protein-coupled receptor signaling pathway (IEA,ISO)

gene expression (ISO)

positive regulation of calcium ion transport (ISO)

positive regulation of collateral sprouting (ISO)

positive regulation of MAPK cascade (ISO)

regulation of metabolic process (IEA)

Cellular Component

axon (ISO)

cytoplasm (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

G-protein alpha-subunit binding (ISO)

lysophosphatidic acid receptor activity (IEA)

phospholipid binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

G protein mediated signaling pathway via Galphaq family (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

LPAR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	48,457,903 - 48,538,754 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	48,485,708 - 48,540,513 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	69,229,208 - 69,311,934 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LPAR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	84,811,602 - 84,893,206 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	84,811,602 - 84,893,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	85,277,285 - 85,358,889 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	85,052,090 - 85,104,430 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	84,991,521 - 85,043,863	NCBI
Celera	1	83,522,972 - 83,602,786 (-)	NCBI		Celera
Cytogenetic Map	1	p22.3	NCBI
HuRef	1	83,389,042 - 83,468,839 (-)	NCBI		HuRef
CHM1_1	1	85,393,947 - 85,473,763 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	84,652,193 - 84,733,814 (-)	NCBI		T2T-CHM13v2.0

Lpar3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	145,926,716 - 145,991,969 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	145,926,718 - 145,991,941 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	146,220,961 - 146,286,214 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	146,220,963 - 146,286,186 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	145,883,925 - 145,949,178 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	146,158,371 - 146,223,572 (+)	NCBI		MGSCv36	mm8
Celera	3	152,671,994 - 152,737,437 (+)	NCBI		Celera
Cytogenetic Map	3	H2	NCBI
cM Map	3	71.03	NCBI

Lpar3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	237,785,371 - 237,854,199 (+)	NCBI		GRCr8
mRatBN7.2	2	235,125,234 - 235,193,916 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	235,149,065 - 235,193,357 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	242,938,279 - 242,984,731 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	240,829,716 - 240,876,162 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	235,695,897 - 235,742,354 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	252,090,634 - 252,159,221 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	252,090,669 - 252,159,903 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	270,610,856 - 270,679,592 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	244,431,789 - 244,510,815 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	244,418,528 - 244,497,555 (+)	NCBI
Celera	2	227,128,872 - 227,173,700 (+)	NCBI		Celera
Cytogenetic Map	2	q44	NCBI

Lpar3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	9,063,804 - 9,133,230 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	9,063,804 - 9,133,203 (+)	NCBI	ChiLan1.0	ChiLan1.0

LPAR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	142,049,603 - 142,131,239 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	141,204,090 - 141,285,732 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	117,359,661 - 117,441,297 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	86,219,789 - 86,274,228 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	86,222,008 - 86,274,228 (-)	Ensembl	panpan1.1		panPan2

LPAR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	63,035,332 - 63,114,697 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	63,035,746 - 63,113,251 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	65,683,188 - 65,761,599 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	63,572,971 - 63,651,406 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	63,596,424 - 63,651,257 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	63,102,662 - 63,181,018 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	63,070,490 - 63,149,065 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	63,578,995 - 63,657,390 (+)	NCBI		UU_Cfam_GSD_1.0

Lpar3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	95,460,869 - 95,534,416 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936608	771,559 - 845,176 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936608	771,618 - 845,176 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LPAR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	128,860,210 - 128,937,763 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	128,860,210 - 128,937,769 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	119,296,648 - 119,374,246 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	6	q2.6-3.2	NCBI

Lpar3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	12,616,910 - 12,691,496 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	12,616,954 - 12,691,226 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium			16
Low	19	17	43
Below cutoff	8	3	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007978117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007978118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000017112 ⟹ ENSCSAP00000016599

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	20	48,485,708 - 48,540,513 (+)	Ensembl

RefSeq Acc Id:

XM_007978118 ⟹ XP_007976309

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	20	48,457,903 - 48,538,754 (+)	NCBI
Vero_WHO_p1.0	NW_023666033	69,229,208 - 69,311,934 (-)	NCBI

Sequence:

show sequence

GGGCGGGGCCGCTACCCCTCGGTCCCTCCCTCGCACTGCCAAACTTTCCTACGGCTCTGGGCGC
GCCGCTGCGGTAGCTGGAGAGGAGGGGTTCCGTCGCCCCCCTGCCCGGCGCGTCCTCCGCTGCT
TGTCCGCACCTAGCTGGAGCCCGGCGCCGGGTGGCTCCGTCGCGCTCGGCCCCGAGGGCATGCG
GCAGCTGCAGGAGCCCCCGCTCCCTGGCTCGGCGGCGCGGGTGAACGTGAGCGGATGTTCACTT
CTTCTCCACAATGAATGAGTGTCACTATGATAAGCACATGGACTTTTTTTATAATAGGAGCAAC
ACTGATACTGTCGATGACTGGACAGGAACAAAGCTTGTGATTGTTTTGTGTGTGGGGTCGTTTT
TCTGCCTGTTTATTTTTTTTTCTAATTCTCTGGTCATTGCGGCAGTGATCAAAAACAGAAAGTT
TCATTTCCCCTTCTACTACCTGTTGGCTAATTTAGCTGCTGCAGATTTCTTCGCTGGAATTGCC
TATGTATTCCTGATGTTTAACACAGGCCCAGTTTCAAAAACTTTGACTGTCAACCGCTGGTTTC
TCCGCCAGGGGCTTCTGGACACTAGCTTGACTGCTTCCCTGACCAACTTGCTGGTTATTGCCGT
GGAGAGGCACGTGTCAATCATGAGGATGCGAGTCCATAGCAACCTGACCAAAAAGAGGGTGACG
CTGCTCATTTTGCTTGTCTGGGCCATCGCCATTTTTATGGGGTCGGTCCCCACACTGGGCTGGA
ATTGCCTCTGCAACATCTCTGCCTGCTCTTCCCTGGCCCCCATTTACAGCAGGAGTTACCTTGT
TTTCTGGACAGTGTCCAACCTCATGGCCTTCTTCATCATGGTTGTGGTGTACCTGCGGATCTAC
ATGTATGTCAAGAGGAAAACCAATGTCTTGTCTCCACATACAAGTGGGTCCATCAGCCGCCGGA
GGACACCGGTGAAGCTCATGAAGACGGTGATGACTGTCTTAGGGGCATTCGTGGTGTGCTGGAC
CCCAGGCCTGGTGGTTCTGCTCCTCGATGGCCTGAATTGCAGGCAGTGTGGTGTGCAGCACGTG
AAAAGGTGGTTCCTGCTGCTGGCGCTGCTTAACTCCGTCATGAACCCCATCATCTACTCCTACA
AGGACGAGGACATGTACGGCACCATGAAGAAGATGATCTGCTGCTTCTCTCAGGAGAACCCAGA
GAGGCGTCCCTCTCGCGTCCCCTCCACGGTCCTCAGCAGGAGTGACACAGGCAGCCAGTACATA
GAGGATAGTATTAGCCAAGGCACAGTCTGCAATAAAAGCAGTTCCTAAACTCTGGACGCCTCTC
TGCCCACCCAGGCCTCCTCTGGGAAAAGAGCTGTTAAGAATGGTTACCTGTCTCTTAACAAAGC
CCATTTACAGTGTTATTTGAGGTCTCCATTAATCACTGCTAGATTTCTTTTAAAAATTGTTTTT
CATAGTTTAAAAGCATGGGCAGTAAAGAGAGGACCTGGTGCATTTAGAGAAAGCACAGAAACGG
GAGAGGTACGGCGGGTCCCTACTTGTCCTGTGAACTGCTCAGAGCTCCTGTCAGTCCGGCTGGG
CCTTCTGGGTTCTGGCACCATTTCGTAGCCATTCTCTTTGTATTTTAAAAGGATGCTATGAAAG
GGCTTAGACCAAAATAAATAATAATGTTACTTGAGCCGCCTTATATAGCTGCTTGGAAAGTCCA
TGTAGTCCTTTCTGCATGCATTAACAATGTTTAGAAATGCTTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007976309	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000016599
	ENSCSAP00000016599.1

RefSeq Acc Id:	XP_007976309 ⟸ XM_007978118
- UniProtKB:	A0A0D9S6W0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000016599 ⟸ ENSCSAT00000017112

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000001421	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000017112.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	LPA_rcpt	UniProtKB/TrEMBL
	LPA_rcpt_EDG7	UniProtKB/TrEMBL
NCBI Gene	LPAR3	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
	LYSOPHOSPHATIDIC ACID RECEPTOR 3	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	EDG7RECEPTOR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/TrEMBL
	LPARECEPTOR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A0D9S6W0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations