NEUROD2 (neuronal differentiation 2) - Rat Genome Database

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Gene: NEUROD2 (neuronal differentiation 2) Chlorocebus sabaeus
Analyze
Symbol: NEUROD2
Name: neuronal differentiation 2
RGD ID: 18761831
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN associative learning (ortholog); behavioral fear response (ortholog); neuron development (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 72 (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurogenic differentiation factor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,557,831 - 66,563,757 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,560,957 - 66,562,105 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607737,471,013 - 37,474,358 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
NEUROD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,557,831 - 66,563,757 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1666,560,957 - 66,562,105 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607737,471,013 - 37,474,358 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NEUROD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381739,603,768 - 39,607,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1739,603,536 - 39,609,777 (-)EnsemblGRCh38hg38GRCh38
GRCh371737,760,021 - 37,764,173 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,013,547 - 35,017,701 (-)NCBINCBI36Build 36hg18NCBI36
Build 341735,014,574 - 35,017,699NCBI
Celera1734,419,756 - 34,423,910 (-)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1733,553,760 - 33,557,911 (-)NCBIHuRef
CHM1_11737,995,843 - 37,999,997 (-)NCBICHM1_1
T2T-CHM13v2.01740,467,334 - 40,471,484 (-)NCBIT2T-CHM13v2.0
Neurod2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,216,241 - 98,220,471 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,216,241 - 98,220,474 (-)EnsemblGRCm39 Ensembl
GRCm381198,325,415 - 98,329,645 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,325,415 - 98,329,648 (-)EnsemblGRCm38mm10GRCm38
MGSCv371198,186,731 - 98,190,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,142,680 - 98,145,735 (-)NCBIMGSCv36mm8
Celera11107,979,699 - 107,983,919 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.75NCBI
Neurod2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81083,820,092 - 83,824,277 (-)NCBIGRCr8
mRatBN7.21083,323,801 - 83,327,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,324,442 - 83,327,986 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1088,268,712 - 88,272,256 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01087,766,799 - 87,770,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01083,159,451 - 83,162,995 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01086,280,865 - 86,282,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,280,892 - 86,282,693 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,077,165 - 86,091,687 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,097,850 - 87,111,300 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11087,112,219 - 87,114,038 (-)NCBI
Celera1082,073,679 - 82,075,495 (-)NCBICelera
Cytogenetic Map10q31NCBI
Neurod2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545114,368,605 - 14,370,544 (-)NCBIChiLan1.0ChiLan1.0
NEUROD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21925,346,953 - 25,351,602 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11727,241,742 - 27,246,400 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01717,680,415 - 17,685,053 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11717,899,078 - 17,900,592 (+)NCBIpanpan1.1PanPan1.1panPan2
NEUROD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,864,708 - 22,869,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,866,212 - 22,867,360 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha922,336,643 - 22,340,973 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0923,657,923 - 23,662,258 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,659,425 - 23,660,573 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1922,430,480 - 22,434,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,691,526 - 22,695,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,816,657 - 22,820,987 (+)NCBIUU_Cfam_GSD_1.0
Neurod2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560222,271,242 - 22,273,510 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649014,802,275 - 14,803,423 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649014,801,636 - 14,803,437 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEUROD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,709,609 - 22,713,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,709,473 - 22,713,785 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21223,162,856 - 23,166,874 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Neurod2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,453,591 - 3,457,625 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,453,525 - 3,457,618 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system nervous system
High
Medium 20
Low 9
Below cutoff 7 12

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008012864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000019129   ⟹   ENSCSAP00000018551
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1666,560,957 - 66,562,105 (+)Ensembl
RefSeq Acc Id: XM_008012864   ⟹   XP_008011055
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11666,557,831 - 66,563,757 (+)NCBI
Vero_WHO_p1.0NW_02366607737,471,013 - 37,474,358 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008011055 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018551
  ENSCSAP00000018551.1
Reference Protein Sequences
RefSeq Acc Id: XP_008011055   ⟸   XM_008012864
- UniProtKB: A0A0D9SCG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000018551   ⟸   ENSCSAT00000019129


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019039 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019129.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Neurogenic_DUF UniProtKB/TrEMBL
  TF_bHLH_NeuroD UniProtKB/TrEMBL
KEGG Report csab:103243540 UniProtKB/TrEMBL
NCBI Gene NEUROD2 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED UniProtKB/TrEMBL
  PTHR19290:SF83 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
  Neuro_bHLH UniProtKB/TrEMBL
PIRSF bHLH_NeuroD UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A0D9SCG2 ENTREZGENE, UniProtKB/TrEMBL