NCCRP1 (NCCRP1, F-box associated domain containing)

Gene: NCCRP1 (NCCRP1, F-box associated domain containing) Chlorocebus sabaeus

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Symbol:

NCCRP1

Name:

NCCRP1, F-box associated domain containing

RGD ID:

18745454

Description:

ENCODES a protein that exhibits ubiquitin protein ligase activity (inferred); INVOLVED IN glycoprotein catabolic process (inferred); positive regulation of cell population proliferation (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); maturity-onset diabetes of the young type 1 (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); SCF ubiquitin ligase complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

F-box only protein 50; non-specific cytotoxic cell receptor protein 1 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	33,786,642 - 33,791,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	33,786,800 - 33,790,581 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	11,815,222 - 11,820,172 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

maturity-onset diabetes of the young type 1 (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycoprotein catabolic process (IEA)

positive regulation of cell population proliferation (IEA)

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

SCF ubiquitin ligase complex (IEA)

Molecular Function

protein binding (ISO)

ubiquitin protein ligase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

NCCRP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	33,786,642 - 33,791,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	33,786,800 - 33,790,581 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	11,815,222 - 11,820,172 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

NCCRP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	39,196,964 - 39,201,884 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	39,196,964 - 39,201,884 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	39,687,604 - 39,692,524 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	44,379,444 - 44,384,362 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	36,491,191 - 36,496,097 (+)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	36,134,453 - 36,139,359 (+)	NCBI		HuRef
CHM1_1	19	39,688,414 - 39,693,332 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	42,001,116 - 42,006,036 (+)	NCBI		T2T-CHM13v2.0

Nccrp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	28,243,017 - 28,247,168 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	28,243,021 - 28,246,679 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	28,543,592 - 28,547,748 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	28,543,596 - 28,547,254 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	29,328,615 - 29,332,273 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	28,252,356 - 28,256,014 (-)	NCBI		MGSCv36	mm8
Celera	7	23,108,697 - 23,112,355 (-)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	16.83	NCBI

Nccrp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	92,962,618 - 92,966,155 (-)	NCBI		GRCr8
mRatBN7.2	1	83,835,083 - 83,838,620 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	83,835,083 - 83,838,676 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	89,245,403 - 89,248,840 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	3,856,311 - 3,859,848 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	91,001,276 - 91,004,713 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	85,558,420 - 85,559,652 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	1	85,213,578 - 85,218,030 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	85,213,652 - 85,217,258 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	86,428,109 - 86,432,474 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	86,767,843 - 86,768,908 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	83,654,277 - 83,657,968 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	83,732,910 - 83,735,887 (-)	NCBI
Celera	1	78,228,998 - 78,233,365 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Nccrp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	353,824 - 356,503 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	353,066 - 356,650 (-)	NCBI	ChiLan1.0	ChiLan1.0

NCCRP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	45,492,854 - 45,496,913 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	47,363,520 - 47,367,520 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	36,295,765 - 36,300,893 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	44,844,060 - 44,849,343 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	44,844,711 - 44,848,796 (+)	Ensembl	panpan1.1		panPan2

NCCRP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	113,989,951 - 113,993,847 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	113,990,024 - 113,993,837 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,391,401 - 113,396,384 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,589,361 - 114,594,343 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,589,434 - 114,592,963 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	114,147,467 - 114,151,134 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	113,780,582 - 113,785,548 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	114,775,712 - 114,779,385 (-)	NCBI		UU_Cfam_GSD_1.0

Nccrp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	13,629,595 - 13,632,450 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	2,057,664 - 2,060,526 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	2,057,664 - 2,060,519 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NCCRP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	47,915,118 - 47,929,937 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	47,925,879 - 47,929,961 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,341,669 - 43,345,771 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Nccrp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	12,514,270 - 12,516,903 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	12,514,223 - 12,517,666 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	7
Low	13	14	4
Below cutoff	4	5	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007996755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000001936 ⟹ ENSCSAP00000000270

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	6	33,786,800 - 33,790,581 (+)	Ensembl

RefSeq Acc Id:

XM_007996755 ⟹ XP_007994946

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	6	33,786,642 - 33,791,701 (+)	NCBI
Vero_WHO_p1.0	NW_023666073	11,815,222 - 11,820,172 (+)	NCBI

Sequence:

show sequence

TGGGAGCCTGGACTCCTGGGTCTGAGGGAGGAGGGTCCGAGGGACAAGATCGTCCCCTGACACG
CCCCTCTCTTAAATGCCAGCCGGGTGCCCTGCCCCTTCCCGCTCCCAGTTAACCCCAGCCCTGC
GAAACCGGGACAGTCGTGCAGCCTCGAGGGATGGAGGAGGTGCGTGAGGGACACGCGTTCGGTG
GCGGGATGGAAGCCGATGGGCCCGCGAGCCCCCAGGAGCTGCCTCCCTCGCCACGGTCGCCGTC
ACCGCCGCCGTCGCCACCACCACTGCCCTCGCCGCCGTCGCTGCCATCGCCCGCGGCCCCGGAG
GCCCCCGAGCTCCCCGAGCCGGAGCAGCCGTCCGAGGTTCACGCCCGGCAGCTGCTGCTGGAGG
AGTGGGGGCCGCTAAGCGGGGGCCTGGAGCTGCCCCCTCGCCTCACCTGGAAGCTGCTCCTGCT
GCGGCGGCCGCTCTACCGCAACCTGCTGCGCTCGCCCAATCCCGAAGGCATCAACATTTATGAG
CCAGCACCCCCTACTGGTCCCACCCAGCGACCCCTGGAGACTCTGGGCAATTTCCGTGGCTGGT
ACATTAGAACCGAAAAGCTTCAGCAGAACCAAAGCTGGACAGTGAAGCAGCAGTGTGTGGACCT
TCTGGCCGAGGGCCTGTGGGAGGAGCTGCTGGATGACGAACAACCAGACATTACAGTCATGGAC
TGGTTCGAGGACAGCCGGCTGGATGCATGTGTCTACGAACTGCACGTCTGGCTCCTGGCAGCCG
ACCGCCGCACGGTCATCGCTCAGCACCATGTGGCCCCCCGAACTTCTGGGAGAGGACCCCCTGG
CCGCTGGGTCCAGGTGTCCCACGTATTCCGCCATTATGGTCCTGGTGTGCGCTTCATCCACTTC
CTGCACAAGGCCAAGAACCGCATGGAGCCTGGTGGGCTGCGGCGGACACGGGTGACTGACTCCT
CCGTGTCTGTGCAGCTCCGGGAGTGACCGGCTGGCTCCTCTGTCCTGACCCCACAGCATCTCCC
TGAGCTTTAGAAGCCCCTAACTCTTAGCCACCTCTTAGGCCCCTTATTCCTCCCCGGCCCTTGG
CTTCTCTCTTGATGGACAGCTTCCACACCCTTAAGCGGTGGAGTCCAGCATTTTCCCGGCACTC
TCTGAGCCCCGTGAGGGCGGAGCCACTCCTTGTAAATTCAGTGCCTGACAGATGCTCTGGCACA
GATGCTCCCTAGATCTCTGTTGAGTGAATGCATAGACACCTGTGCTCAAGGATGCTGAGGGCTG
GTCTCTGCTTCTTTGAACTTCACTGAAACTGAATGCTTACTGCTGTGTTGCCAGCACCACCCAG
CCCAGGGCTATGAGCAGAGTGGCAGTGAATGTCTGTTGAAGGCGGAATGGAGCCATTCATTTCA
CTCAGTTCCTGTCCCATTTAACCGCCCCTGATCCTTGATCTTCCACTACCTTCACACCCCAGGG
TCCTTCTGAACTGACCTTGACCTCTGATCTCTTCACACATCTCCCCTTAGCATCTCTACTTACC
TACTCTCCTTTTATTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGGAGAGCAGTGACA
CAATCTTGGCTCACTCCAATTTCCACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCTCG
AGTAGGGATTACAGGTGCCCACCACCACGCCCACTAATTTTTGTATTTTAGTAGAGACAGGGTT
TCACCATGTTGGCTAGGCTGGTCTCAAACTCCTGACCTCAAGCGATCCACCCACCTTGGCCTTC
CAAAGTGCTGGGATTGCAGACGTGAGTCACTGCGCCTGGCCATTCCATATCTCTTGAGTCTCAG
AATTTCCTCTAGCTCCCTCCAGGTGTCTGCAGTTGTCGTCCCCTCAAAGCTGTCCCACACTCTC
CTCCGAAGACCCTTTGTGTATCTTCTCCAGCTACCGCAGACCCCCCAAACCCAGGCATCCATCA
AAGTCCCTCATTCATGAGGGTGTGGGGACACAGACTGTGACCAGAACAGAAATATGAAAATGTG
AATGACAGTGTCCCCCATGTGTGGAATGTGGGGATTAAAAGCATTTATCAACCACTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007994946	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000000270
	ENSCSAP00000000270.1

RefSeq Acc Id:	XP_007994946 ⟸ XM_007996755
- UniProtKB:	A0A0D9QV81 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000000270 ⟸ ENSCSAT00000001936

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000003907	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000001936.1	UniProtKB/TrEMBL
Gene3D-CATH	Galactose-binding domain-like	UniProtKB/TrEMBL
InterPro	F-box-assoc_dom	UniProtKB/TrEMBL
	F-box_only	UniProtKB/TrEMBL
	Galactose-bd-like_sf	UniProtKB/TrEMBL
KEGG Report	csab:103234657	UniProtKB/TrEMBL
NCBI Gene	NCCRP1	ENTREZGENE
PANTHER	F-BOX ONLY PROTEIN 50	UniProtKB/TrEMBL
	PTHR12125	UniProtKB/TrEMBL
Pfam	FBA	UniProtKB/TrEMBL
PROSITE	FBA	UniProtKB/TrEMBL
SMART	FBA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49785	UniProtKB/TrEMBL
UniProt	A0A0D9QV81	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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