PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta) - Rat Genome Database

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Gene: PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta) Chlorocebus sabaeus
Analyze
Symbol: PIK3C2B
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
RGD ID: 18675748
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (inferred); 1-phosphatidylinositol-4-phosphate 3-kinase activity (inferred); ATP binding (inferred); INVOLVED IN autophagosome organization (ortholog); cellular response to starvation (ortholog); macroautophagy (ortholog); ASSOCIATED WITH autistic disorder (ortholog); familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endocytic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12524,855,712 - 24,926,050 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2524,855,766 - 24,926,346 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605525,615,537 - 25,686,367 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PIK3C2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12524,855,712 - 24,926,050 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2524,855,766 - 24,926,346 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605525,615,537 - 25,686,367 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PIK3C2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381204,422,633 - 204,494,805 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1204,422,628 - 204,494,805 (-)EnsemblGRCh38hg38GRCh38
GRCh371204,391,761 - 204,463,933 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361202,658,384 - 202,726,097 (-)NCBINCBI36Build 36hg18NCBI36
Build 341201,123,420 - 201,191,131NCBI
Celera1177,527,172 - 177,594,672 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1175,556,880 - 175,624,580 (-)NCBIHuRef
CHM1_11205,815,608 - 205,882,878 (-)NCBICHM1_1
T2T-CHM13v2.01203,687,208 - 203,759,206 (-)NCBIT2T-CHM13v2.0
Pik3c2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,973,410 - 133,036,429 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,973,405 - 133,036,425 (+)EnsemblGRCm39 Ensembl
GRCm381133,045,672 - 133,108,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,045,667 - 133,108,687 (+)EnsemblGRCm38mm10GRCm38
MGSCv371134,942,589 - 135,005,265 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361134,873,558 - 134,934,994 (+)NCBIMGSCv36mm8
Celera1135,655,035 - 135,720,282 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.75NCBI
Pik3c2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81347,046,866 - 47,107,733 (+)NCBIGRCr8
mRatBN7.21344,494,673 - 44,555,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1344,495,050 - 44,555,612 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1347,101,804 - 47,160,253 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01348,389,909 - 48,448,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01345,650,489 - 45,709,098 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01349,848,939 - 49,909,404 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1349,850,189 - 49,911,202 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01354,919,438 - 54,977,791 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41345,954,337 - 46,013,206 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11345,987,757 - 46,027,587 (+)NCBI
Celera1344,829,361 - 44,887,236 (+)NCBICelera
Cytogenetic Map13q13NCBI
Pik3c2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540640,247,382 - 40,317,556 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540640,247,690 - 40,317,556 (-)NCBIChiLan1.0ChiLan1.0
PIK3C2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2144,882,135 - 44,960,492 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1144,847,333 - 44,920,688 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,024,889 - 180,096,287 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,313,233 - 184,384,454 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,313,233 - 184,384,454 (-)Ensemblpanpan1.1panPan2
PIK3C2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.138974,248 - 1,016,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl38975,749 - 1,027,679 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha381,069,379 - 1,134,940 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.038969,737 - 1,035,426 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl38969,759 - 1,035,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.138966,025 - 1,031,937 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0381,357,807 - 1,423,477 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0381,557,935 - 1,623,716 (-)NCBIUU_Cfam_GSD_1.0
Pik3c2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934471,080,285 - 71,142,927 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936567314,898 - 378,045 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936567314,957 - 377,544 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3C2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl965,073,738 - 65,154,538 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1965,073,728 - 65,154,861 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2971,409,230 - 71,490,324 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pik3c2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248076,554,926 - 6,612,831 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248076,543,665 - 6,612,833 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12
Low 36 20 48
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012636   ⟹   ENSCSAP00000010667
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2524,855,766 - 24,926,346 (+)Ensembl
RefSeq Acc Id: XM_007988803   ⟹   XP_007986994
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12524,855,716 - 24,926,050 (+)NCBI
Vero_WHO_p1.0NW_02366605525,615,537 - 25,686,367 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007988804   ⟹   XP_007986995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12524,855,712 - 24,916,335 (+)NCBI
Vero_WHO_p1.0NW_02366605525,615,537 - 25,676,695 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007986994 (Get FASTA)   NCBI Sequence Viewer  
  XP_007986995 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010667.1
Reference Protein Sequences
RefSeq Acc Id: XP_007986995   ⟸   XM_007988804
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RPX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986994   ⟸   XM_007988803
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RPX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000010667   ⟸   ENSCSAT00000012636


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014548 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012636.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/TrEMBL
  1.25.40.70 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Phox UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI3K_accessory_sf UniProtKB/TrEMBL
  PI3K_C2_dom UniProtKB/TrEMBL
  PI3K_Ras-bd_dom UniProtKB/TrEMBL
  PI_Kinase UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  PX_PI3K_C2_beta UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report csab:103230248 UniProtKB/TrEMBL
NCBI Gene PIK3C2B ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA UniProtKB/TrEMBL
  PTHR10048 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PI3_PI4_kinase UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
PROSITE PI3_4_KINASE_1 UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/TrEMBL
  PI3K_RBD UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  PS50195 UniProtKB/TrEMBL
SMART PI3K_C2 UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
  PI3Kc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A0D9RPX8 ENTREZGENE, UniProtKB/TrEMBL