CDK5RAP3 (CDK5 regulatory subunit associated protein 3) - Rat Genome Database

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Gene: CDK5RAP3 (CDK5 regulatory subunit associated protein 3) Chlorocebus sabaeus
Analyze
Symbol: CDK5RAP3
Name: CDK5 regulatory subunit associated protein 3
RGD ID: 18672660
Description: ENCODES a protein that exhibits cyclin binding (ortholog); MDM2/MDM4 family protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN apoptotic nuclear changes (ortholog); cell population proliferation (ortholog); definitive erythrocyte differentiation (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDK5 regulatory subunit-associated protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,367,591 - 68,382,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,303 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CDK5RAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11668,367,591 - 68,382,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,303 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CDK5RAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,967,904 - 47,981,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,967,810 - 47,981,781 (+)EnsemblGRCh38hg38GRCh38
GRCh371746,047,894 - 46,059,147 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,403,428 - 43,414,146 (+)NCBINCBI36Build 36hg18NCBI36
Build 341743,403,427 - 43,414,146NCBI
Celera1742,501,248 - 42,511,966 (+)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1741,416,597 - 41,427,853 (+)NCBIHuRef
CHM1_11746,112,862 - 46,124,122 (+)NCBICHM1_1
T2T-CHM13v2.01748,829,702 - 48,843,580 (+)NCBIT2T-CHM13v2.0
Cdk5rap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,798,251 - 96,807,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,798,252 - 96,807,322 (-)EnsemblGRCm39 Ensembl
GRCm381196,907,425 - 96,916,531 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,907,426 - 96,916,496 (-)EnsemblGRCm38mm10GRCm38
MGSCv371196,769,100 - 96,777,795 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,723,876 - 96,732,571 (-)NCBIMGSCv36mm8
Celera11106,553,602 - 106,563,974 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1160.16NCBI
Cdk5rap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81082,390,845 - 82,402,814 (-)NCBIGRCr8
mRatBN7.21081,894,393 - 81,903,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,894,393 - 81,903,590 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1086,842,458 - 86,851,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01086,340,506 - 86,349,660 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,733,108 - 81,742,263 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01084,780,644 - 84,789,800 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,780,608 - 84,789,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01084,571,933 - 84,581,074 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1080,656,149 - 80,665,286 (-)NCBICelera
Cytogenetic Map10q31NCBI
Cdk5rap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,120,761 - 13,170,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,160,811 - 13,170,012 (-)NCBIChiLan1.0ChiLan1.0
CDK5RAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,122,187 - 17,134,982 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,087,819 - 19,098,641 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0179,556,313 - 9,567,099 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,738,144 - 9,748,989 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,738,141 - 9,749,302 (-)Ensemblpanpan1.1panPan2
CDK5RAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,276,660 - 24,286,273 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,276,768 - 24,286,272 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha923,742,863 - 23,752,452 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,070,151 - 25,079,744 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,070,173 - 25,079,745 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1923,840,058 - 23,849,636 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,101,046 - 24,110,629 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,227,612 - 24,237,208 (+)NCBIUU_Cfam_GSD_1.0
Cdk5rap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560223,719,423 - 23,729,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649013,345,443 - 13,355,841 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649013,345,443 - 13,355,841 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK5RAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,224,263 - 24,234,467 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,224,262 - 24,234,468 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,044,526 - 24,053,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Cdk5rap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247954,594,207 - 4,602,583 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247954,594,131 - 4,602,435 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 54
Low 18 6
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000000581   ⟹   ENSCSAP00000015482
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1668,370,483 - 68,382,022 (+)Ensembl
RefSeq Acc Id: XM_008012975   ⟹   XP_008011166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,370,832 - 68,382,000 (+)NCBI
Vero_WHO_p1.0NW_02366607739,423,081 - 39,434,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012976   ⟹   XP_008011167
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,371,251 - 68,381,973 (+)NCBI
Vero_WHO_p1.0NW_02366607739,423,481 - 39,434,302 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008012978   ⟹   XP_008011169
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11668,367,591 - 68,382,000 (+)NCBI
Vero_WHO_p1.0NW_02366607739,422,747 - 39,434,302 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037993238   ⟹   XP_037849166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,492 - 39,434,302 (+)NCBI
RefSeq Acc Id: XM_037993239   ⟹   XP_037849167
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,175 - 39,434,302 (+)NCBI
RefSeq Acc Id: XM_037993240   ⟹   XP_037849168
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607739,423,081 - 39,434,296 (+)NCBI
RefSeq Acc Id: XP_008011169   ⟸   XM_008012978
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008011166   ⟸   XM_008012975
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008011167   ⟸   XM_008012976
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015482   ⟸   ENSCSAT00000000581
RefSeq Acc Id: XP_037849168   ⟸   XM_037993240
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037849167   ⟸   XM_037993239
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037849166   ⟸   XM_037993238
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S3P3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002562 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000581.1 UniProtKB/TrEMBL
InterPro CDK5RAP3 UniProtKB/TrEMBL
KEGG Report csab:103243591 UniProtKB/TrEMBL
NCBI Gene CDK5RAP3 ENTREZGENE
PANTHER CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 UniProtKB/TrEMBL
  PTHR14894 UniProtKB/TrEMBL
Pfam DUF773 UniProtKB/TrEMBL
UniProt A0A0D9S3P3 ENTREZGENE, UniProtKB/TrEMBL