SLC25A21 (solute carrier family 25 member 21) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SLC25A21 (solute carrier family 25 member 21) Chlorocebus sabaeus
Analyze
Symbol: SLC25A21
Name: solute carrier family 25 member 21
RGD ID: 18668931
Description: ENCODES a protein that exhibits alpha-ketoglutarate transmembrane transporter activity (inferred); antiporter activity (inferred); INVOLVED IN mitochondrial alpha-ketoglutarate transmembrane transport (inferred); ASSOCIATED WITH anodontia (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); choreatic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial 2-oxodicarboxylate carrier
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12413,472,050 - 13,974,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2413,473,395 - 13,680,176 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660532,472,343 - 3,007,377 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
SLC25A21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12413,472,050 - 13,974,991 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2413,473,395 - 13,680,176 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660532,472,343 - 3,007,377 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC25A21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381436,677,921 - 37,172,606 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1436,677,921 - 37,172,606 (-)EnsemblGRCh38hg38GRCh38
GRCh371437,147,126 - 37,641,811 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361436,218,829 - 36,711,616 (-)NCBINCBI36Build 36hg18NCBI36
Build 341436,218,828 - 36,711,616NCBI
Celera1417,010,674 - 17,505,455 (-)NCBICelera
Cytogenetic Map14q13.3NCBI
HuRef1417,261,499 - 17,756,171 (-)NCBIHuRef
CHM1_11437,146,272 - 37,641,918 (-)NCBICHM1_1
T2T-CHM13v2.01430,867,261 - 31,362,039 (-)NCBIT2T-CHM13v2.0
Slc25a21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391256,759,419 - 57,244,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1256,759,419 - 57,244,257 (-)EnsemblGRCm39 Ensembl
GRCm381256,712,634 - 57,197,472 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1256,712,634 - 57,197,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv371257,813,621 - 58,298,459 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361257,630,836 - 58,115,484 (-)NCBIMGSCv36mm8
Celera1257,878,480 - 58,364,481 (-)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1224.54NCBI
Slc25a21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8679,938,480 - 80,437,937 (-)NCBIGRCr8
mRatBN7.2674,203,439 - 74,702,902 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl674,203,440 - 74,702,680 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx674,616,827 - 75,122,323 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0674,916,140 - 75,421,635 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0674,343,605 - 74,849,121 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0677,624,384 - 78,121,339 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl677,624,385 - 77,848,434 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0687,150,622 - 87,637,326 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4677,124,451 - 77,632,510 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1677,127,574 - 77,635,636 (-)NCBI
Celera673,010,400 - 73,501,204 (-)NCBICelera
Cytogenetic Map6q23NCBI
Slc25a21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540923,952,595 - 24,421,307 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540923,949,794 - 24,421,944 (+)NCBIChiLan1.0ChiLan1.0
SLC25A21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21537,993,058 - 38,490,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11437,209,563 - 37,708,394 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01417,431,789 - 17,926,277 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11435,793,261 - 36,287,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1435,794,557 - 35,990,633 (-)Ensemblpanpan1.1panPan2
SLC25A21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1815,239,634 - 15,708,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl815,238,719 - 15,708,526 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha815,039,326 - 15,508,864 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0815,350,597 - 15,821,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl815,350,762 - 15,821,128 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1815,049,508 - 15,519,554 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0815,116,588 - 15,586,598 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0815,406,571 - 15,876,813 (-)NCBIUU_Cfam_GSD_1.0
Slc25a21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864047,169,640 - 47,650,696 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649410,676,235 - 11,156,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649410,675,534 - 11,157,829 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl762,810,937 - 63,325,625 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1762,808,126 - 63,326,634 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2768,085,398 - 68,235,406 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Slc25a21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483875,767 - 128,843 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462483868,999 - 129,463 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 16 41
Below cutoff 3 19

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013552   ⟹   ENSCSAP00000011547
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2413,473,395 - 13,680,176 (-)Ensembl
RefSeq Acc Id: XM_007986522   ⟹   XP_007984713
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12413,472,050 - 13,974,991 (-)NCBI
Vero_WHO_p1.0NW_0236660532,472,343 - 3,007,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037983906   ⟹   XP_037839834
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660532,472,343 - 3,007,377 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007984713 (Get FASTA)   NCBI Sequence Viewer  
  XP_037839834 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011547
  ENSCSAP00000011547.1
Reference Protein Sequences
RefSeq Acc Id: XP_007984713   ⟸   XM_007986522
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RSF8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011547   ⟸   ENSCSAT00000013552
RefSeq Acc Id: XP_037839834   ⟸   XM_037983906
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RSF8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015457 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013552.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
NCBI Gene SLC25A21 ENTREZGENE
PANTHER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER UniProtKB/TrEMBL
  MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
UniProt A0A0D9RSF8 ENTREZGENE, UniProtKB/TrEMBL