PABIR1 (PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1) - Rat Genome Database

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Gene: PABIR1 (PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1) Chlorocebus sabaeus
Analyze
Symbol: PABIR1
Name: PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
RGD ID: 18665566
Description: ENCODES a protein that exhibits protein serine/threonine phosphatase inhibitor activity (inferred); INVOLVED IN positive regulation of cell growth (ortholog); positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAM122A; family with sequence similarity 122A; protein FAM122A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11279,877,288 - 79,879,862 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1279,877,416 - 79,878,279 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603868,283,246 - 68,287,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PABIR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11279,877,288 - 79,879,862 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1279,877,416 - 79,878,279 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603868,283,246 - 68,287,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PABIR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38968,780,065 - 68,785,566 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl968,780,065 - 68,785,566 (+)EnsemblGRCh38hg38GRCh38
GRCh37971,394,981 - 71,400,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36970,584,784 - 70,588,429 (+)NCBINCBI36Build 36hg18NCBI36
Build 34968,624,517 - 68,628,163NCBI
Celera941,990,151 - 41,993,796 (+)NCBICelera
Cytogenetic Map9q21.11NCBI
HuRef941,240,535 - 41,244,180 (+)NCBIHuRef
CHM1_1971,542,188 - 71,545,833 (+)NCBICHM1_1
T2T-CHM13v2.0980,953,589 - 80,959,090 (+)NCBIT2T-CHM13v2.0
Pabir1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391924,451,270 - 24,454,819 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1924,453,866 - 24,454,720 (-)EnsemblGRCm39 Ensembl
GRCm381924,475,779 - 24,477,474 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1924,476,502 - 24,477,356 (-)EnsemblGRCm38mm10GRCm38
MGSCv371924,550,269 - 24,551,964 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361924,542,874 - 24,544,571 (-)NCBIMGSCv36mm8
Celera1925,245,132 - 25,246,827 (-)NCBICelera
Cytogenetic Map19BNCBI
cM Map1919.53NCBI
Pabir1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81231,541,411 - 231,542,717 (-)NCBIGRCr8
mRatBN7.21222,114,988 - 222,116,294 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,112,591 - 222,116,396 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1230,569,504 - 230,570,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,499,564 - 237,500,870 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01230,317,572 - 230,318,878 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01242,372,458 - 242,373,764 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,372,458 - 242,373,764 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,645,665 - 249,646,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,891,961 - 227,893,267 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,055,985 - 228,057,290 (-)NCBI
Celera1219,325,874 - 219,327,180 (-)NCBICelera
Cytogenetic Map1q51NCBI
Pabir1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554344,250,105 - 4,251,508 (-)NCBIChiLan1.0ChiLan1.0
PABIR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21167,990,179 - 67,994,514 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1967,996,121 - 67,997,502 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0956,007,323 - 56,011,655 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1967,544,336 - 67,548,928 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl967,544,489 - 67,545,352 (+)Ensemblpanpan1.1panPan2
PABIR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1188,580,008 - 88,587,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha189,051,624 - 89,054,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0189,130,513 - 89,133,147 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1188,775,055 - 88,782,390 (-)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.0189,251,913 - 89,254,544 (-)NCBIUU_Cfam_GSD_1.0
Pabir1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947136,069,528 - 136,077,031 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365035,096,112 - 5,096,963 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365035,095,986 - 5,097,274 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PABIR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11222,114,314 - 222,122,337 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,522,179 - 248,524,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pabir1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247364,340,195 - 4,341,058 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247364,333,707 - 4,341,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 42
Low 20 18
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007969428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000018587   ⟹   ENSCSAP00000018036
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1279,877,416 - 79,878,279 (+)Ensembl
RefSeq Acc Id: XM_007969428   ⟹   XP_007967619
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11279,877,288 - 79,879,862 (+)NCBI
Vero_WHO_p1.0NW_02366603868,283,246 - 68,287,889 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007967619 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018036
  ENSCSAP00000018036.1
Reference Protein Sequences
RefSeq Acc Id: XP_007967619   ⟸   XM_007969428
RefSeq Acc Id: ENSCSAP00000018036   ⟸   ENSCSAT00000018587


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018497 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018587.1 UniProtKB/TrEMBL
InterPro FAM122 UniProtKB/TrEMBL
NCBI Gene FAM122A ENTREZGENE
PANTHER PPP2R1A-PPP2R2A-INTERACTING PHOSPHATASE REGULATOR 1 UniProtKB/TrEMBL
  PTHR22227 UniProtKB/TrEMBL
UniProt A0A0D9SAZ7_CHLSB UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-10-13 PABIR1  PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1  FAM122A  family with sequence similarity 122A  Symbol and/or name change 5135510 APPROVED