TESC (tescalcin) - Rat Genome Database

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Gene: TESC (tescalcin) Chlorocebus sabaeus
Analyze
Symbol: TESC
Name: tescalcin
RGD ID: 18638485
Description: ENCODES a protein that exhibits magnesium ion binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN male gonad development (ortholog); megakaryocyte development (ortholog); megakaryocyte differentiation (ortholog); FOUND IN ruffle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: calcineurin B homologous protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111112,331,123 - 112,410,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11112,327,906 - 112,410,849 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037132,669,841 - 132,746,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TESC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111112,331,123 - 112,410,901 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11112,327,906 - 112,410,849 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037132,669,841 - 132,746,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TESC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812117,038,923 - 117,099,416 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12117,038,923 - 117,099,479 (-)EnsemblGRCh38hg38GRCh38
GRCh3712117,476,728 - 117,537,221 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612115,961,111 - 116,021,634 (-)NCBINCBI36Build 36hg18NCBI36
Celera12117,106,248 - 117,166,769 (-)NCBICelera
Cytogenetic Map12q24.22NCBI
HuRef12114,485,557 - 114,546,137 (-)NCBIHuRef
CHM1_112117,444,429 - 117,505,233 (-)NCBICHM1_1
T2T-CHM13v2.012117,019,980 - 117,080,464 (-)NCBIT2T-CHM13v2.0
Tesc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395118,165,808 - 118,199,943 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5118,165,808 - 118,199,943 (+)EnsemblGRCm39 Ensembl
GRCm385118,027,743 - 118,061,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5118,027,743 - 118,061,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv375118,477,833 - 118,511,879 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365118,288,854 - 118,322,900 (+)NCBIMGSCv36mm8
Celera5115,122,941 - 115,156,704 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map557.84NCBI
Tesc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,182,741 - 44,216,574 (-)NCBIGRCr8
mRatBN7.21238,521,832 - 38,555,665 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1238,521,861 - 38,555,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1239,697,181 - 39,730,981 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,310,977 - 40,344,777 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01239,363,938 - 39,397,741 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01244,141,258 - 44,174,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1244,141,422 - 44,174,583 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,972,890 - 46,006,329 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,669,706 - 39,704,041 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1240,180,191 - 40,225,489 (-)NCBICelera
Cytogenetic Map12q16NCBI
Tesc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545514,053,443 - 14,092,637 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545514,053,918 - 14,092,637 (+)NCBIChiLan1.0ChiLan1.0
TESC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210125,099,855 - 125,160,624 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112125,096,237 - 125,157,013 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012114,615,155 - 114,675,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112117,991,047 - 118,051,370 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12117,991,047 - 118,051,346 (-)Ensemblpanpan1.1panPan2
TESC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12613,645,513 - 13,700,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2613,645,511 - 13,689,367 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2613,639,965 - 13,687,307 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02613,905,740 - 13,953,098 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2613,905,738 - 13,953,775 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12613,867,524 - 13,914,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02613,944,789 - 13,999,699 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02613,980,002 - 14,027,402 (-)NCBIUU_Cfam_GSD_1.0
Tesc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118154,062,082 - 154,103,256 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365585,398,393 - 5,417,368 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365585,397,018 - 5,417,335 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TESC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1435,381,923 - 35,439,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11435,381,899 - 35,452,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21437,601,263 - 37,658,113 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tesc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474716,188,949 - 16,228,211 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474716,189,032 - 16,228,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12 4 32
Low 24 16 28
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000000342   ⟹   ENSCSAP00000015712
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11112,327,906 - 112,410,849 (-)Ensembl
RefSeq Acc Id: XM_008004854   ⟹   XP_008003045
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111112,347,599 - 112,410,898 (-)NCBI
Vero_WHO_p1.0NW_023666037132,669,881 - 132,730,682 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004855   ⟹   XP_008003046
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111112,347,599 - 112,410,896 (-)NCBI
Vero_WHO_p1.0NW_023666037132,669,868 - 132,730,682 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037996473   ⟹   XP_037852401
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037132,669,879 - 132,730,682 (+)NCBI
RefSeq Acc Id: XM_037996474   ⟹   XP_037852402
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037132,669,861 - 132,746,806 (+)NCBI
RefSeq Acc Id: XM_037996475   ⟹   XP_037852403
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037132,669,841 - 132,730,682 (+)NCBI
RefSeq Acc Id: XR_005239839
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037132,669,862 - 132,730,682 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008003045 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003046 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852401 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852402 (Get FASTA)   NCBI Sequence Viewer  
  XP_037852403 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015712.1
RefSeq Acc Id: XP_008003045   ⟸   XM_008004854
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S4C3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003046   ⟸   XM_008004855
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S4C3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015712   ⟸   ENSCSAT00000000342
RefSeq Acc Id: XP_037852403   ⟸   XM_037996475
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037852402   ⟸   XM_037996474
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S4C3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037852401   ⟸   XM_037996473
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002325 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000342.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
NCBI Gene TESC ENTREZGENE
PANTHER CALCINEURIN B HOMOLOGOUS PROTEIN 3 UniProtKB/TrEMBL
  CALCINEURIN B HOMOLOGOUS PROTEIN 3 UniProtKB/TrEMBL
Pfam EF-hand_6 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0D9S4C3 ENTREZGENE, UniProtKB/TrEMBL