ARHGAP32 (Rho GTPase activating protein 32) - Rat Genome Database

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Gene: ARHGAP32 (Rho GTPase activating protein 32) Chlorocebus sabaeus
Analyze
Symbol: ARHGAP32
Name: Rho GTPase activating protein 32
RGD ID: 18618892
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN cerebellum development (ortholog); positive regulation of axon extension (ortholog); positive regulation of neuron migration (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 32
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11120,108,671 - 120,333,200 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1120,112,042 - 120,329,370 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660435,674,740 - 5,987,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGAP32
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11120,108,671 - 120,333,200 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1120,112,042 - 120,329,370 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660435,674,740 - 5,987,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ARHGAP32
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,965,060 - 129,279,632 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11128,965,060 - 129,279,324 (-)EnsemblGRCh38hg38GRCh38
GRCh3711128,834,955 - 129,149,413 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,343,052 - 128,399,222 (-)NCBINCBI36Build 36hg18NCBI36
Celera11126,003,454 - 126,230,572 (-)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11124,785,776 - 125,014,078 (-)NCBIHuRef
CHM1_111128,721,150 - 128,948,156 (-)NCBICHM1_1
T2T-CHM13v2.011128,999,975 - 129,315,124 (-)NCBIT2T-CHM13v2.0
Arhgap32
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39931,927,921 - 32,176,061 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,027,432 - 32,179,742 (+)EnsemblGRCm39 Ensembl
GRCm38932,016,625 - 32,268,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,116,136 - 32,268,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv37931,923,721 - 32,072,084 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36931,957,765 - 32,010,849 (+)NCBIMGSCv36mm8
Celera929,377,749 - 29,526,489 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.48NCBI
Arhgap32
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8838,679,368 - 38,939,960 (+)NCBIGRCr8
mRatBN7.2830,421,269 - 30,681,653 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl830,421,515 - 30,678,454 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0833,131,874 - 33,392,198 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,239,139 - 33,392,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,168,863 - 33,409,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4831,859,986 - 32,032,203 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,005,344 - 32,040,895 (+)NCBI
Celera831,879,179 - 32,135,024 (+)NCBICelera
Cytogenetic Map8q21NCBI
Arhgap32
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541229,910,395 - 30,203,340 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541229,910,395 - 30,113,959 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP32
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29129,648,795 - 129,966,615 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111130,756,565 - 131,074,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011123,780,028 - 124,096,494 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111127,680,804 - 127,882,212 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,684,622 - 127,909,822 (-)Ensemblpanpan1.1panPan2
ARHGAP32
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.155,398,833 - 5,690,041 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl55,380,831 - 5,686,840 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha55,460,004 - 5,750,414 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.055,358,554 - 5,649,847 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl55,340,445 - 5,646,077 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.155,419,701 - 5,709,873 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.055,402,897 - 5,693,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.055,430,554 - 5,721,803 (+)NCBIUU_Cfam_GSD_1.0
Arhgap32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947111,157,285 - 111,454,036 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365723,118,670 - 3,294,109 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365723,100,695 - 3,293,077 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP32
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,906,954 - 56,177,551 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,903,365 - 56,177,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,997,185 - 62,009,623 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Arhgap32
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248123,282,299 - 3,597,436 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248123,278,564 - 3,474,004 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 15 55
Low 21 16 5
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000231   ⟹   ENSCSAP00000015822
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1120,112,042 - 120,329,370 (-)Ensembl
RefSeq Acc Id: XM_008021488   ⟹   XP_008019679
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11120,108,671 - 120,333,200 (-)NCBI
Vero_WHO_p1.0NW_0236660435,763,550 - 5,987,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021489   ⟹   XP_008019680
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11120,108,671 - 120,330,419 (-)NCBI
Vero_WHO_p1.0NW_0236660435,763,550 - 5,987,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021490   ⟹   XP_008019681
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11120,108,671 - 120,306,101 (-)NCBI
Vero_WHO_p1.0NW_0236660435,786,694 - 5,987,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021493   ⟹   XP_008019684
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11120,108,671 - 120,309,230 (-)NCBI
Vero_WHO_p1.0NW_0236660435,782,954 - 5,987,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021497   ⟹   XP_008019688
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11120,108,671 - 120,173,599 (-)NCBI
Vero_WHO_p1.0NW_0236660435,922,195 - 5,987,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038004998   ⟹   XP_037860926
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660435,674,740 - 5,987,192 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008019679   ⟸   XM_008021488
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019680   ⟸   XM_008021489
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019684   ⟸   XM_008021493
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019681   ⟸   XM_008021490
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019688   ⟸   XM_008021497
- Peptide Label: isoform X5
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015822   ⟸   ENSCSAT00000000231
RefSeq Acc Id: XP_037860926   ⟸   XM_038004998
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S4N3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002226 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000231.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro PX_ARHGAP32 UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene ARHGAP32 ENTREZGENE
PANTHER CDC42 GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 32 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A0D9S4N3 ENTREZGENE, UniProtKB/TrEMBL