BAZ1B (bromodomain adjacent to zinc finger domain 1B) - Rat Genome Database

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Pathways
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Gene: BAZ1B (bromodomain adjacent to zinc finger domain 1B) Chlorocebus sabaeus
Analyze
Symbol: BAZ1B
Name: bromodomain adjacent to zinc finger domain 1B
RGD ID: 18611331
Description: ENCODES a protein that exhibits histone binding (inferred); histone H2AXY142 kinase activity (inferred); histone kinase activity (inferred); INVOLVED IN chromatin organization (ortholog); chromatin remodeling (ortholog); negative regulation of mitotic chromosome condensation (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ISWI family mediated chromatin remodeling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); intestinal volvulus (ortholog); FOUND IN B-WICH complex (ortholog); condensed chromosome (ortholog); nuclear replication fork (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein kinase BAZ1B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,533,802 - 9,617,164 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,534,114 - 9,617,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660706,855,992 - 6,938,041 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BAZ1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,533,802 - 9,617,164 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,534,114 - 9,617,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660706,855,992 - 6,938,041 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BAZ1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,440,406 - 73,522,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,440,406 - 73,522,293 (-)EnsemblGRCh38hg38GRCh38
GRCh37772,854,736 - 72,936,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,492,676 - 72,574,544 (-)NCBINCBI36Build 36hg18NCBI36
Build 34772,299,383 - 72,381,200NCBI
Celera768,332,639 - 68,414,529 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef768,736,057 - 68,818,392 (-)NCBIHuRef
CHM1_1773,000,196 - 73,082,038 (-)NCBICHM1_1
T2T-CHM13v2.0774,640,900 - 74,722,781 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,187,800 - 72,269,687 (-)NCBI
Baz1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,214,094 - 135,274,985 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,216,118 - 135,274,983 (+)EnsemblGRCm39 Ensembl
GRCm385135,187,323 - 135,246,131 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,187,264 - 135,246,129 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,663,193 - 135,721,999 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365135,471,986 - 135,529,194 (+)NCBIMGSCv36mm8
Celera5132,199,039 - 132,257,800 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.05NCBI
Baz1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,068,541 - 27,126,511 (-)NCBIGRCr8
mRatBN7.21221,431,985 - 21,489,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,431,985 - 21,490,426 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,573,589 - 22,631,630 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,185,918 - 23,243,954 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,252,394 - 22,310,416 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,478,882 - 24,536,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,478,898 - 24,537,313 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,476,185 - 26,534,154 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,586,411 - 22,644,378 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1223,194,558 - 23,252,515 (-)NCBICelera
Cytogenetic Map12q12NCBI
Baz1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,185,107 - 14,240,688 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545614,185,091 - 14,242,391 (+)NCBIChiLan1.0ChiLan1.0
BAZ1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2691,379,549 - 91,461,458 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17139,644,104 - 139,726,092 (+)NCBINHGRI_mPanPan1
PanPan1.1780,594,629 - 80,675,645 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,594,626 - 80,675,709 (-)Ensemblpanpan1.1panPan2
BAZ1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,709,648 - 6,776,904 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,709,697 - 6,776,867 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha68,406,933 - 8,475,941 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.066,524,701 - 6,594,233 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,524,385 - 6,592,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,514,050 - 6,569,390 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,461,859 - 6,531,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,625,515 - 6,694,618 (+)NCBIUU_Cfam_GSD_1.0
Baz1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,246,801 - 131,322,970 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,713,589 - 2,779,993 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,713,575 - 2,779,947 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAZ1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,761,499 - 10,843,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1310,761,461 - 10,843,918 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,460,760 - 10,543,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Baz1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,248,274 - 14,319,823 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474014,247,972 - 14,319,713 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 15 60
Low 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016264   ⟹   ENSCSAP00000014184
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl289,534,114 - 9,617,190 (+)Ensembl
RefSeq Acc Id: XM_008018350   ⟹   XP_008016541
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1289,533,802 - 9,617,164 (+)NCBI
Vero_WHO_p1.0NW_0236660706,855,995 - 6,938,041 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008018351   ⟹   XP_008016542
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1289,533,802 - 9,617,164 (+)NCBI
Vero_WHO_p1.0NW_0236660706,855,992 - 6,937,895 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008016541 (Get FASTA)   NCBI Sequence Viewer  
  XP_008016542 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014184.1
Reference Protein Sequences
RefSeq Acc Id: XP_008016541   ⟸   XM_008018350
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008016542   ⟸   XM_008018351
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000014184   ⟸   ENSCSAT00000016264


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018168 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016264.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro BAZ1B UniProtKB/TrEMBL
  BAZ1B_Bromo UniProtKB/TrEMBL
  BAZ1B_PHD UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  DDT_dom UniProtKB/TrEMBL
  WHIM1_dom UniProtKB/TrEMBL
  WHIM2_dom UniProtKB/TrEMBL
  WSTF_Acf1_Cbp146 UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report csab:103246637 UniProtKB/TrEMBL
NCBI Gene BAZ1B ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE BAZ1B UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE BAZ1B UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  WAC_Acf1_DNA_bd UniProtKB/TrEMBL
  WHIM1 UniProtKB/TrEMBL
  WSD UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  WAC UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
  DDT UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A0D9RZZ5_CHLSB UniProtKB/TrEMBL