SFXN5 (sideroflexin 5) - Rat Genome Database

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Gene: SFXN5 (sideroflexin 5) Chlorocebus sabaeus
Analyze
Symbol: SFXN5
Name: sideroflexin 5
RGD ID: 18597397
Description: ENCODES a protein that exhibits citrate transmembrane transporter activity (ortholog); INVOLVED IN citrate transport (ortholog); ASSOCIATED WITH Alstrom syndrome (ortholog); congenital disorder of glycosylation type IIb (ortholog); dystonia (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sideroflexin-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11434,095,375 - 34,224,716 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1434,095,538 - 34,221,744 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SFXN5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11434,095,375 - 34,224,716 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1434,095,538 - 34,221,744 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SFXN5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38272,942,036 - 73,071,712 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl272,942,036 - 73,075,619 (-)EnsemblGRCh38hg38GRCh38
GRCh37273,169,165 - 73,298,841 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,022,673 - 73,152,473 (-)NCBINCBI36Build 36hg18NCBI36
Build 34273,080,820 - 73,210,620NCBI
Celera273,020,012 - 73,149,807 (-)NCBICelera
Cytogenetic Map2p13.2NCBI
HuRef272,904,762 - 73,034,523 (-)NCBIHuRef
CHM1_1273,099,350 - 73,229,443 (-)NCBICHM1_1
T2T-CHM13v2.0272,954,982 - 73,084,686 (-)NCBIT2T-CHM13v2.0
Sfxn5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,190,031 - 85,310,488 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,190,031 - 85,310,404 (-)EnsemblGRCm39 Ensembl
GRCm38685,213,049 - 85,333,482 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,213,049 - 85,333,422 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,163,045 - 85,283,416 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,178,712 - 85,299,077 (-)NCBIMGSCv36mm8
Celera687,185,070 - 87,305,385 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.23NCBI
Sfxn5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,307,692 - 119,427,531 (-)NCBIGRCr8
mRatBN7.24117,750,213 - 117,869,826 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4117,752,806 - 117,869,794 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,234,024 - 123,351,071 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,009,152 - 119,126,193 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04117,622,318 - 117,739,577 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04116,995,238 - 117,111,548 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4116,993,914 - 117,111,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,575,048 - 181,691,684 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,462,697 - 119,583,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14119,707,177 - 119,827,844 (-)NCBI
Celera4106,735,952 - 106,852,599 (-)NCBICelera
Cytogenetic Map4q34NCBI
Sfxn5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,545,985 - 12,659,293 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,545,985 - 12,659,238 (+)NCBIChiLan1.0ChiLan1.0
SFXN5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21253,308,686 - 53,438,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A53,311,436 - 53,441,559 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A72,994,664 - 73,125,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A74,487,505 - 74,617,200 (-)NCBIpanpan1.1PanPan1.1panPan2
SFXN5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,773,446 - 49,896,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,773,883 - 49,894,400 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1749,420,233 - 49,542,918 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,640,156 - 50,762,822 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1750,640,581 - 50,762,817 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11749,656,289 - 49,778,999 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,723,146 - 49,844,580 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01750,281,844 - 50,404,595 (+)NCBIUU_Cfam_GSD_1.0
Sfxn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,688,516 - 11,801,334 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649116,769,979 - 16,882,781 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649116,769,960 - 16,882,776 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFXN5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,701,149 - 69,839,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,701,021 - 69,833,971 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,903,534 - 73,033,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sfxn5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624762563,027 - 678,324 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624762563,023 - 685,375 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 60
Low 19
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000013415   ⟹   ENSCSAP00000011417
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1434,095,538 - 34,221,744 (+)Ensembl
RefSeq Acc Id: XM_007970241   ⟹   XP_007968432
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11434,095,375 - 34,224,716 (+)NCBI
Vero_WHO_p1.0NW_02366604577,855,539 - 77,985,851 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038007098   ⟹   XP_037863026
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,918 (-)NCBI
RefSeq Acc Id: XM_038007099   ⟹   XP_037863027
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,871 (-)NCBI
RefSeq Acc Id: XM_038007100   ⟹   XP_037863028
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,871 (-)NCBI
RefSeq Acc Id: XM_038007101   ⟹   XP_037863029
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,984,602 (-)NCBI
RefSeq Acc Id: XM_038007102   ⟹   XP_037863030
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,971,129 (-)NCBI
RefSeq Acc Id: XM_038007103   ⟹   XP_037863031
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,985,914 (-)NCBI
RefSeq Acc Id: XM_038007104   ⟹   XP_037863032
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,535 - 77,912,632 (-)NCBI
RefSeq Acc Id: XR_005243419
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604577,855,738 - 77,985,870 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007968432   ⟸   XM_007970241
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RS28 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000011417   ⟸   ENSCSAT00000013415
RefSeq Acc Id: XP_037863026   ⟸   XM_038007098
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037863031   ⟸   XM_038007103
- Peptide Label: isoform X6
RefSeq Acc Id: XP_037863028   ⟸   XM_038007100
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037863027   ⟸   XM_038007099
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037863029   ⟸   XM_038007101
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037863030   ⟸   XM_038007102
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037863032   ⟸   XM_038007104
- Peptide Label: isoform X7


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013415.1 UniProtKB/TrEMBL
InterPro Mtc UniProtKB/TrEMBL
NCBI Gene SFXN5 ENTREZGENE
PANTHER PTHR11153 UniProtKB/TrEMBL
  SIDEROFLEXIN-5 UniProtKB/TrEMBL
Pfam Mtc UniProtKB/TrEMBL
UniProt A0A0D9RS28 ENTREZGENE, UniProtKB/TrEMBL