SPART (spartin) - Rat Genome Database

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Gene: SPART (spartin) Chlorocebus sabaeus
Analyze
Symbol: SPART
Name: spartin
RGD ID: 18590957
Description: ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN abscission (ortholog); adipose tissue development (ortholog); BMP signaling pathway (ortholog); ASSOCIATED WITH cerebellar ataxia (ortholog); esophagus adenocarcinoma (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: spastic paraplegia 20 (Troyer syndrome); SPG20
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1314,887,896 - 14,925,296 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl314,886,633 - 14,924,865 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605729,368,466 - 29,405,924 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPART
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1314,887,896 - 14,925,296 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl314,886,633 - 14,924,865 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605729,368,466 - 29,405,924 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SPART
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381336,301,638 - 36,370,180 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1336,301,638 - 36,370,180 (-)EnsemblGRCh38hg38GRCh38
GRCh371336,875,775 - 36,944,317 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361335,773,775 - 35,818,453 (-)NCBINCBI36Build 36hg18NCBI36
Build 341335,773,776 - 35,818,453NCBI
Celera1317,942,963 - 18,011,514 (-)NCBICelera
Cytogenetic Map13q13.3NCBI
HuRef1317,687,578 - 17,756,402 (-)NCBIHuRef
CHM1_11336,843,258 - 36,911,860 (-)NCBICHM1_1
T2T-CHM13v2.01335,521,139 - 35,589,682 (-)NCBIT2T-CHM13v2.0
Spart
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39355,019,500 - 55,044,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl355,019,529 - 55,044,743 (+)EnsemblGRCm39 Ensembl
GRCm38355,112,108 - 55,137,332 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl355,112,108 - 55,137,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv37354,916,030 - 54,941,254 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36355,200,069 - 55,223,886 (+)NCBIMGSCv36mm8
Celera354,829,886 - 54,855,111 (+)NCBICelera
Cytogenetic Map3CNCBI
cM Map326.53NCBI
Spart
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82141,442,770 - 141,469,388 (+)NCBIGRCr8
mRatBN7.22139,292,630 - 139,319,248 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2139,292,355 - 139,319,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2145,867,478 - 145,894,087 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02143,978,916 - 144,005,524 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02138,611,347 - 138,637,957 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02144,522,382 - 144,548,968 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2144,522,072 - 144,548,917 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02163,938,864 - 163,965,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42144,335,236 - 144,362,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12144,290,137 - 144,310,595 (+)NCBI
Celera2133,776,474 - 133,803,061 (+)NCBICelera
Cytogenetic Map2q26NCBI
Spart
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554319,758,053 - 9,786,644 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554319,758,159 - 9,786,468 (+)NCBIChiLan1.0ChiLan1.0
SPART
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21435,827,216 - 35,894,535 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11326,933,228 - 27,000,539 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01317,514,720 - 17,582,011 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11335,944,556 - 35,989,775 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1335,945,938 - 35,989,774 (-)Ensemblpanpan1.1panPan2
SPART
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,256,177 - 4,302,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl254,232,533 - 4,316,363 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,288,086 - 4,334,989 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0254,357,038 - 4,404,379 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl254,333,554 - 4,389,355 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1254,264,422 - 4,311,754 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0254,260,116 - 4,307,054 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0254,323,956 - 4,371,292 (+)NCBIUU_Cfam_GSD_1.0
Spart
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945165,426,341 - 165,484,173 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647230,467,964 - 30,504,624 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647230,467,975 - 30,525,880 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPART
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1112,313,210 - 12,374,645 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11112,313,211 - 12,346,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21112,264,432 - 12,281,379 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Spart
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247761,065,600 - 1,104,938 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 39
Low 20 21
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000015973   ⟹   ENSCSAP00000013898
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl314,886,633 - 14,924,865 (-)Ensembl
RefSeq Acc Id: XM_007960137   ⟹   XP_007958328
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1314,887,896 - 14,924,891 (-)NCBI
Vero_WHO_p1.0NW_02366605729,368,807 - 29,405,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007960138   ⟹   XP_007958329
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1314,887,896 - 14,925,296 (-)NCBI
Vero_WHO_p1.0NW_02366605729,368,466 - 29,405,924 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007960139   ⟹   XP_007958330
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1314,887,896 - 14,924,891 (-)NCBI
Vero_WHO_p1.0NW_02366605729,368,840 - 29,405,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037986811   ⟹   XP_037842739
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605729,368,466 - 29,405,924 (+)NCBI
RefSeq Acc Id: XM_037986812   ⟹   XP_037842740
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605729,369,626 - 29,405,919 (+)NCBI
RefSeq Acc Id: XP_007958329   ⟸   XM_007960138
- UniProtKB: A0A0D9RZ59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007958330   ⟸   XM_007960139
- UniProtKB: A0A0D9RZ59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007958328   ⟸   XM_007960137
- UniProtKB: A0A0D9RZ59 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013898   ⟸   ENSCSAT00000015973
RefSeq Acc Id: XP_037842739   ⟸   XM_037986811
- UniProtKB: A0A0D9RZ59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842740   ⟸   XM_037986812
- UniProtKB: A0A0D9RZ59 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017878 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015973.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/TrEMBL
InterPro MIT UniProtKB/TrEMBL
  MIT_dom_sf UniProtKB/TrEMBL
  Senescence/spartin UniProtKB/TrEMBL
  Spartin-like UniProtKB/TrEMBL
KEGG Report csab:103214279 UniProtKB/TrEMBL
NCBI Gene SPART ENTREZGENE
PANTHER PTHR21068 UniProtKB/TrEMBL
  SPARTIN UniProtKB/TrEMBL
Pfam Senescence UniProtKB/TrEMBL
SMART MIT UniProtKB/TrEMBL
Superfamily-SCOP SSF116846 UniProtKB/TrEMBL
UniProt A0A0D9RZ59 ENTREZGENE, UniProtKB/TrEMBL