SDCBP (syndecan binding protein) - Rat Genome Database

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Gene: SDCBP (syndecan binding protein) Chlorocebus sabaeus
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Symbol: SDCBP
Name: syndecan binding protein
RGD ID: 18586705
Description: ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); ephrin receptor binding (ortholog); frizzled binding (ortholog); INVOLVED IN negative regulation of receptor internalization (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of cell growth (ortholog); PARTICIPATES IN interleukin-5 signaling pathway; syndecan signaling pathway; ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN cytosol (ortholog); extracellular exosome (ortholog); interleukin-5 receptor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103236850; syntenin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1854,536,286 - 54,565,884 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,388 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SDCBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1854,536,286 - 54,565,884 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,388 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SDCBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38858,553,261 - 58,582,858 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl858,552,924 - 58,582,859 (+)EnsemblGRCh38hg38GRCh38
GRCh37859,465,820 - 59,495,417 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36859,628,282 - 59,657,973 (+)NCBINCBI36Build 36hg18NCBI36
Build 34859,628,281 - 59,657,972NCBI
Celera855,458,752 - 55,488,443 (+)NCBICelera
Cytogenetic Map8q12.1NCBI
HuRef854,952,903 - 54,982,593 (+)NCBIHuRef
CHM1_1859,517,611 - 59,547,302 (+)NCBICHM1_1
T2T-CHM13v2.0858,974,408 - 59,004,011 (+)NCBIT2T-CHM13v2.0
Sdcbp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3946,365,713 - 6,396,120 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl46,365,650 - 6,408,423 (+)EnsemblGRCm39 Ensembl
GRCm3846,365,680 - 6,396,122 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl46,365,650 - 6,408,423 (+)EnsemblGRCm38mm10GRCm38
MGSCv3746,292,827 - 6,323,269 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3646,292,868 - 6,322,797 (+)NCBIMGSCv36mm8
Celera46,283,969 - 6,314,409 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map42.91NCBI
Sdcbp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8524,245,279 - 24,314,712 (+)NCBIGRCr8
mRatBN7.2519,473,499 - 19,517,188 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl519,489,961 - 19,527,572 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx521,697,118 - 21,724,119 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0523,288,429 - 23,315,152 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0523,068,735 - 23,095,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0519,471,664 - 19,498,499 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl519,471,664 - 19,498,485 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0524,256,110 - 24,283,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4519,822,440 - 19,849,223 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1519,822,439 - 19,849,220 (+)NCBI
Celera518,790,757 - 18,817,395 (+)NCBICelera
Cytogenetic Map5q12NCBI
Sdcbp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545417,089,232 - 17,113,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545417,093,930 - 17,113,491 (+)NCBIChiLan1.0ChiLan1.0
SDCBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2774,231,999 - 74,264,164 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1849,885,857 - 49,918,036 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0854,992,627 - 55,022,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1856,643,962 - 56,673,834 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl856,643,962 - 56,673,833 (+)Ensemblpanpan1.1panPan2
SDCBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1299,331,876 - 9,370,489 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha299,644,617 - 9,683,238 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0299,417,267 - 9,455,907 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl299,417,305 - 9,455,885 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1299,415,389 - 9,453,988 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0299,541,083 - 9,579,672 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0299,820,349 - 9,859,247 (+)NCBIUU_Cfam_GSD_1.0
Sdcbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530360,438,300 - 60,453,495 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649614,331,662 - 14,347,197 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649614,331,971 - 14,347,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SDCBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl474,295,922 - 74,341,085 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1474,295,941 - 74,357,720 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2481,090,105 - 81,122,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sdcbp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474433,524,416 - 33,557,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474433,524,045 - 33,558,963 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 60
Low
Below cutoff

Sequence


RefSeq Acc Id: XM_008000708   ⟹   XP_007998899
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1854,536,286 - 54,565,884 (+)NCBI
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,388 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008000709   ⟹   XP_007998900
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1854,536,286 - 54,565,884 (+)NCBI
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,343 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008000710   ⟹   XP_007998901
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1854,536,496 - 54,565,666 (+)NCBI
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,082 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008000711   ⟹   XP_007998902
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1854,536,286 - 54,565,884 (+)NCBI
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,367 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008000712   ⟹   XP_007998903
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1854,536,286 - 54,565,884 (+)NCBI
Vero_WHO_p1.0NW_02366603987,157,660 - 87,187,349 (-)NCBI
Sequence:
RefSeq Acc Id: XP_007998899   ⟸   XM_008000708
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998902   ⟸   XM_008000711
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998900   ⟸   XM_008000709
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998903   ⟸   XM_008000712
- Peptide Label: isoform X2
- UniProtKB: A0A0D9SBF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998901   ⟸   XM_008000710
- Peptide Label: isoform X1
- UniProtKB: A0A0D9SBF6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014518 ENTREZGENE, UniProtKB/TrEMBL
  ENSCSAG00000018673 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012612.1 UniProtKB/TrEMBL
  ENSCSAT00000018763.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene SDCBP ENTREZGENE
PANTHER PTHR12345:SF10 UniProtKB/TrEMBL
  SYNTENIN RELATED UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A0D9RPV3_CHLSB UniProtKB/TrEMBL
  A0A0D9SBF6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 SDCBP  syndecan binding protein  LOC103236850  syndecan binding protein  Symbol and/or name change 5135510 APPROVED
2020-12-08 LOC103236850  syndecan binding protein  SDCBP  syndecan binding protein  Symbol and/or name change 5135510 APPROVED