CCDC8 (coiled-coil domain containing 8) - Rat Genome Database

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Gene: CCDC8 (coiled-coil domain containing 8) Chlorocebus sabaeus
Analyze
Symbol: CCDC8
Name: coiled-coil domain containing 8
RGD ID: 18584304
Description: INVOLVED IN microtubule cytoskeleton organization (inferred); regulation of mitotic nuclear division (inferred); ASSOCIATED WITH genetic disease (ortholog); Three M Syndrome 3 (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil domain-containing protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,793,931 - 39,796,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,794,179 - 39,795,819 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,472,138 - 19,475,446 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CCDC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,793,931 - 39,796,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,794,179 - 39,795,819 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,472,138 - 19,475,446 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CCDC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,410,329 - 46,413,564 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,410,329 - 46,413,564 (-)EnsemblGRCh38hg38GRCh38
GRCh371946,913,586 - 46,916,821 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,605,925 - 51,608,681 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,605,928 - 51,608,681NCBI
Celera1943,718,552 - 43,721,888 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,341,075 - 43,344,411 (-)NCBIHuRef
CHM1_11946,915,521 - 46,918,858 (-)NCBICHM1_1
T2T-CHM13v2.01949,237,640 - 49,240,878 (-)NCBIT2T-CHM13v2.0
Ccdc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,727,827 - 16,731,440 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,726,633 - 16,731,441 (+)EnsemblGRCm39 Ensembl
GRCm38716,993,902 - 16,997,515 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,992,708 - 16,997,516 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,579,937 - 17,581,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36717,579,937 - 17,581,994 (+)NCBIMGSCv36mm8
Celera714,201,787 - 14,203,844 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Ccdc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,807,607 - 86,810,935 (+)NCBIGRCr8
mRatBN7.2177,679,521 - 77,682,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,679,218 - 77,683,090 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx183,059,619 - 83,062,971 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,623,686 - 91,627,038 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,814,724 - 84,818,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,933,372 - 78,936,700 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,933,372 - 78,936,700 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0180,180,875 - 80,184,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,334,504 - 77,337,832 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,412,614 - 77,415,946 (+)NCBI
Celera172,164,565 - 72,167,893 (+)NCBICelera
Cytogenetic Map1q21NCBI
Ccdc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955574551,582 - 553,829 (-)NCBIChiLan1.0ChiLan1.0
CCDC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,556,769 - 52,561,762 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,427,500 - 54,432,890 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,399,711 - 43,403,207 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,929,302 - 51,932,355 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,928,645 - 51,931,510 (-)Ensemblpanpan1.1panPan2
CCDC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,349,965 - 109,354,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,352,047 - 109,353,612 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,829,144 - 108,833,529 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,876,129 - 109,880,330 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11109,552,986 - 109,557,370 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,187,080 - 109,191,732 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,055,960 - 110,060,345 (-)NCBIUU_Cfam_GSD_1.0
Ccdc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,811,581 - 18,814,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664430,411 - 432,256 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664429,733 - 432,673 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,476,117 - 52,477,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,474,508 - 52,478,257 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,679,728 - 47,682,688 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ccdc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248327,089,777 - 7,092,557 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 32 20
Low 4 13 40
Below cutoff 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007997294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000019722   ⟹   ENSCSAP00000019128
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl639,794,179 - 39,795,819 (-)Ensembl
RefSeq Acc Id: XM_007997294   ⟹   XP_007995485
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1639,793,931 - 39,796,665 (-)NCBI
Vero_WHO_p1.0NW_02366607319,472,138 - 19,475,446 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000019128
  ENSCSAP00000019128.1
Reference Protein Sequences
RefSeq Acc Id: XP_007995485   ⟸   XM_007997294
- UniProtKB: A0A0D9SE39 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000019128   ⟸   ENSCSAT00000019722


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019722.1 UniProtKB/TrEMBL
InterPro Coiled-coil_p8 UniProtKB/TrEMBL
KEGG Report csab:103234908 UniProtKB/TrEMBL
NCBI Gene CCDC8 ENTREZGENE
PANTHER COILED COIL DOMAIN-CONTAINING PROTEIN 8, CCDC8 UniProtKB/TrEMBL
  COILED-COIL DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
UniProt A0A0D9SE39 ENTREZGENE, UniProtKB/TrEMBL