RASGRP2 (RAS guanyl releasing protein 2) - Rat Genome Database

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Gene: RASGRP2 (RAS guanyl releasing protein 2) Chlorocebus sabaeus
Analyze
Symbol: RASGRP2
Name: RAS guanyl releasing protein 2
RGD ID: 18581426
Description: ENCODES a protein that exhibits calcium ion binding (inferred); guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to calcium ion (ortholog); ASSOCIATED WITH genetic disease (ortholog); hemorrhagic disease (ortholog); high grade glioma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); neuron projection (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RAS guanyl-releasing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,483,557 - 9,508,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,492,624 - 9,508,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,881,231 - 106,897,854 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RASGRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,483,557 - 9,508,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,492,624 - 9,508,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,881,231 - 106,897,854 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RASGRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,726,911 - 64,745,456 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1164,726,911 - 64,745,456 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,494,383 - 64,512,928 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,250,959 - 64,269,504 (-)NCBINCBI36Build 36hg18NCBI36
Build 341164,250,958 - 64,269,504NCBI
Celera1161,820,826 - 61,839,372 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1160,821,353 - 60,854,156 (-)NCBIHuRef
CHM1_11164,378,122 - 64,396,623 (-)NCBICHM1_1
T2T-CHM13v2.01164,720,142 - 64,738,685 (-)NCBIT2T-CHM13v2.0
Rasgrp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,449,038 - 6,465,243 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,449,370 - 6,465,246 (+)EnsemblGRCm39 Ensembl
GRCm38196,398,957 - 6,415,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,399,340 - 6,415,216 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,400,583 - 6,415,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,400,562 - 6,415,213 (+)NCBIMGSCv36mm8
Celera196,273,600 - 6,288,233 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.58NCBI
Rasgrp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,135,034 - 213,152,246 (+)NCBIGRCr8
mRatBN7.21203,705,777 - 203,722,993 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,707,481 - 203,722,993 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,056,314 - 212,072,133 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01219,152,807 - 219,168,318 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,843,860 - 211,859,371 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,771,238 - 221,788,765 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,773,254 - 221,788,765 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,759,339 - 228,776,703 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,183,700 - 209,199,170 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,342,129 - 209,357,590 (+)NCBI
Celera1201,240,896 - 201,256,235 (+)NCBICelera
Cytogenetic Map1q43NCBI
Rasgrp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,425,002 - 20,440,810 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,426,241 - 20,440,540 (+)NCBIChiLan1.0ChiLan1.0
RASGRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2965,952,157 - 65,971,777 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11166,995,154 - 67,014,774 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,081,781 - 60,101,400 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,423,112 - 63,443,240 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,423,112 - 63,440,917 (-)Ensemblpanpan1.1panPan2
RASGRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,412,331 - 52,426,910 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,412,367 - 52,426,916 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1851,019,635 - 51,034,051 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,453,534 - 53,467,923 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1853,455,079 - 53,468,115 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11852,548,448 - 52,562,832 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01852,134,369 - 52,148,760 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,918,511 - 52,932,911 (+)NCBIUU_Cfam_GSD_1.0
Rasgrp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049478,124,840 - 8,137,258 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365994,567,385 - 4,579,607 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASGRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,422,846 - 7,440,404 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,424,805 - 7,440,404 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,554,977 - 6,573,074 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rasgrp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,640,430 - 21,656,073 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,640,619 - 21,655,989 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 9 20 23
Low 27 37
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000005285   ⟹   ENSCSAP00000003508
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl19,492,624 - 9,508,912 (+)Ensembl
RefSeq Acc Id: XM_037997351   ⟹   XP_037853279
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038106,881,231 - 106,897,854 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037853279 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003508.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000003508   ⟸   ENSCSAT00000005285
RefSeq Acc Id: XP_037853279   ⟸   XM_037997351
- UniProtKB: A0A0D9R4G9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007242 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005285.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras-like_Gua-exchang_fac_N UniProtKB/TrEMBL
  Ras_GEF_dom_sf UniProtKB/TrEMBL
  RASGEF_cat_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
NCBI Gene RASGRP2 ENTREZGENE
PANTHER PTHR23113 UniProtKB/TrEMBL
  RAS GUANYL-RELEASING PROTEIN 2 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  RasGEF_N UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
  RASGEF_NTER UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  RasGEFN UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF48366 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A0D9R4G9 ENTREZGENE, UniProtKB/TrEMBL