DHFR2 (dihydrofolate reductase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: DHFR2 (dihydrofolate reductase 2) Chlorocebus sabaeus
Analyze
Symbol: DHFR2
Name: dihydrofolate reductase 2
RGD ID: 18577629
Description: ENCODES a protein that exhibits dihydrofolate reductase activity (ortholog); mRNA binding (ortholog); INVOLVED IN tetrahydrofolate metabolic process (ortholog); thymidine biosynthetic process (ortholog); ASSOCIATED WITH autosomal recessive thrombophilia due to protein S deficiency (ortholog); Joubert syndrome 8 (ortholog); protein S deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dihydrofolate reductase 2, mitochondrial
RGD Orthologs
Human
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12286,643,325 - 86,645,418 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604180,034,856 - 80,038,329 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DHFR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12286,643,325 - 86,645,418 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604180,034,856 - 80,038,329 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DHFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38394,057,922 - 94,063,320 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl394,047,836 - 94,063,389 (-)EnsemblGRCh38hg38GRCh38
GRCh37393,776,766 - 93,781,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36395,259,456 - 95,264,350 (-)NCBINCBI36Build 36hg18NCBI36
Build 34395,259,459 - 95,264,350NCBI
Celera392,160,656 - 92,165,546 (-)NCBICelera
Cytogenetic Map3q11.2NCBI
HuRef391,139,383 - 91,144,684 (-)NCBIHuRef
CHM1_1393,739,771 - 93,745,071 (-)NCBICHM1_1
T2T-CHM13v2.0396,756,374 - 96,761,771 (-)NCBIT2T-CHM13v2.0
DHFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2291,969,773 - 91,973,343 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1391,977,561 - 91,979,720 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0391,125,295 - 91,128,378 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1397,802,727 - 97,807,705 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC609048
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11916,731,187 - 16,731,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1916,944,408 - 16,945,045 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01916,843,375 - 16,844,037 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11916,800,539 - 16,801,196 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01917,078,604 - 17,079,266 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01917,550,180 - 17,550,815 (+)NCBIUU_Cfam_GSD_1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038003208   ⟹   XP_037859136
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604180,034,856 - 80,038,329 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037859136 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_037859136   ⟸   XM_038003208


Additional Information

Database Acc Id Source(s)
NCBI Gene DHFR2 ENTREZGENE