TTC28 (tetratricopeptide repeat domain 28) - Rat Genome Database

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Gene: TTC28 (tetratricopeptide repeat domain 28) Chlorocebus sabaeus
Analyze
Symbol: TTC28
Name: tetratricopeptide repeat domain 28
RGD ID: 18557390
Description: ENCODES a protein that exhibits kinase binding (inferred); INVOLVED IN regulation of mitotic cell cycle (inferred); ASSOCIATED WITH Familial Prostate Cancer (ortholog); FOUND IN midbody (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tetratricopeptide repeat protein 28
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11910,883,566 - 11,559,332 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1910,887,702 - 11,334,237 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045115,116,542 - 115,236,796 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
midbody  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TTC28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11910,883,566 - 11,559,332 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1910,887,702 - 11,334,237 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045115,116,542 - 115,236,796 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TTC28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382227,978,014 - 28,679,840 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2227,978,014 - 28,679,840 (-)EnsemblGRCh38hg38GRCh38
GRCh372228,374,002 - 29,075,828 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362226,704,002 - 27,405,853 (-)NCBINCBI36Build 36hg18NCBI36
Celera2212,173,962 - 12,875,814 (-)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef2211,338,617 - 12,040,439 (-)NCBIHuRef
CHM1_12228,333,275 - 29,034,916 (-)NCBICHM1_1
T2T-CHM13v2.02228,439,435 - 29,141,276 (-)NCBIT2T-CHM13v2.0
Ttc28
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395111,027,652 - 111,437,646 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5111,027,669 - 111,437,646 (+)EnsemblGRCm39 Ensembl
GRCm385110,879,785 - 111,289,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5110,879,803 - 111,289,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv375111,308,822 - 111,718,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365111,464,223 - 111,527,433 (+)NCBIMGSCv36mm8
Celera5108,012,516 - 108,409,441 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.74NCBI
Ttc28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81251,002,816 - 51,443,461 (-)NCBIGRCr8
mRatBN7.21245,342,986 - 45,783,968 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,345,399 - 45,783,547 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01251,385,808 - 51,840,710 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1251,385,763 - 51,702,730 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01253,127,157 - 53,578,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,479,987 - 45,927,996 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1246,908,661 - 47,343,197 (-)NCBICelera
Cytogenetic Map12q16NCBI
Ttc28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554552,325,010 - 2,747,519 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554552,322,290 - 2,964,259 (-)NCBIChiLan1.0ChiLan1.0
TTC28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22337,974,170 - 38,678,278 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12240,673,158 - 41,377,335 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0229,030,021 - 9,749,142 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12226,749,171 - 27,407,650 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2226,753,335 - 26,941,509 (-)Ensemblpanpan1.1panPan2
TTC28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12621,424,249 - 22,049,579 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2621,427,961 - 22,240,624 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2621,296,028 - 21,921,221 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02621,791,433 - 22,422,646 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2621,794,896 - 22,422,785 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12621,508,751 - 22,133,080 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02621,763,432 - 22,396,706 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02621,833,583 - 22,458,996 (-)NCBIUU_Cfam_GSD_1.0
Ttc28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118113,069,819 - 113,661,198 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366572,212,808 - 2,308,742 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366572,209,509 - 2,800,879 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1445,320,600 - 45,925,098 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11445,317,793 - 45,925,026 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21448,211,174 - 48,377,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ttc28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247474,312,204 - 4,477,492 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247474,308,288 - 5,029,860 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 3 20
Low 33 20 40
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000008075   ⟹   ENSCSAP00000006230
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1910,887,702 - 11,334,237 (-)Ensembl
RefSeq Acc Id: XM_038006302   ⟹   XP_037862230
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045115,116,542 - 115,236,796 (+)NCBI
RefSeq Acc Id: XM_038006303   ⟹   XP_037862231
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045115,116,542 - 115,236,796 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037862230 (Get FASTA)   NCBI Sequence Viewer  
  XP_037862231 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006230.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000006230   ⟸   ENSCSAT00000008075
RefSeq Acc Id: XP_037862230   ⟸   XM_038006302
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037862231   ⟸   XM_038006303
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009988 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008075.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro CHAT_dom UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene TTC28 ENTREZGENE
PANTHER RAPSYN-RELATED UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 28 UniProtKB/TrEMBL
Pfam CHAT UniProtKB/TrEMBL
  TPR_12 UniProtKB/TrEMBL
  TPR_7 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
  TPR_REGION UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0D9RC91_CHLSB UniProtKB/TrEMBL