TFR2 (transferrin receptor 2) - Rat Genome Database

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Gene: TFR2 (transferrin receptor 2) Chlorocebus sabaeus
Analyze
Symbol: TFR2
Name: transferrin receptor 2
RGD ID: 18552913
Description: ENCODES a protein that exhibits co-receptor binding (inferred); transferrin receptor activity (inferred); INVOLVED IN acute-phase response (ortholog); multicellular organismal-level iron ion homeostasis (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); beta thalassemia (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic vesicle (inferred); external side of plasma membrane (inferred); HFE-transferrin receptor complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transferrin receptor protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,570,604 - 12,592,269 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,571,841 - 12,592,266 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,712,690 - 3,733,677 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TFR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,570,604 - 12,592,269 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,571,841 - 12,592,266 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,712,690 - 3,733,677 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,620,420 - 100,641,552 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,620,416 - 100,642,779 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,218,043 - 100,239,175 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,055,975 - 100,077,109 (-)NCBINCBI36Build 36hg18NCBI36
Build 34799,862,690 - 99,883,810NCBI
Celera794,947,821 - 94,968,950 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,849,520 - 94,870,648 (-)NCBIHuRef
CHM1_17100,148,586 - 100,169,685 (-)NCBICHM1_1
T2T-CHM13v2.07101,860,501 - 101,881,634 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,577,671 - 99,598,799 (-)NCBI
Tfr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,568,127 - 137,586,344 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,568,102 - 137,585,743 (+)EnsemblGRCm39 Ensembl
GRCm385137,569,822 - 137,588,081 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,569,840 - 137,587,481 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,011,079 - 138,028,709 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,800,593 - 137,817,260 (+)NCBIMGSCv36mm8
Celera5134,553,519 - 134,571,033 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.57NCBI
Tfr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,744,450 - 24,761,413 (-)NCBIGRCr8
mRatBN7.21219,107,673 - 19,124,622 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,107,673 - 19,124,591 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,263,117 - 20,280,127 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,875,998 - 20,893,008 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,940,332 - 19,957,342 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,177,382 - 22,194,330 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,177,382 - 22,194,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,194,288 - 24,211,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,638,502 - 19,655,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11219,628,960 - 19,644,982 (+)NCBI
Celera1220,912,852 - 20,929,749 (-)NCBICelera
Cytogenetic Map12q12NCBI
Tfr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573272,289 - 291,668 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573272,315 - 289,227 (+)NCBIChiLan1.0ChiLan1.0
TFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,531,714 - 118,554,217 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,796,330 - 166,818,842 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,647,431 - 92,669,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,048,497 - 106,060,481 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,048,935 - 106,069,238 (-)Ensemblpanpan1.1panPan2
TFR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,059,501 - 9,076,646 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,060,629 - 9,076,158 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,763,917 - 10,781,061 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.068,993,681 - 9,010,842 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl68,993,652 - 9,010,354 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,846,198 - 8,863,361 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,823,694 - 8,841,037 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,006,114 - 9,023,274 (+)NCBIUU_Cfam_GSD_1.0
Tfr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,353,500 - 133,368,393 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543668,157 - 682,174 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543667,570 - 681,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,539,320 - 8,578,763 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,539,316 - 8,553,993 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,934,261 - 7,948,960 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tfr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,452,504 - 16,466,781 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,451,520 - 16,469,393 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 20 19 37
Below cutoff 15 1 23

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016023   ⟹   ENSCSAP00000013948
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2812,571,841 - 12,592,266 (+)Ensembl
RefSeq Acc Id: XM_008018525   ⟹   XP_008016716
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12812,570,604 - 12,592,269 (+)NCBI
Vero_WHO_p1.0NW_0236660703,712,690 - 3,733,677 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008016716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013948.1
Reference Protein Sequences
RefSeq Acc Id: XP_008016716   ⟸   XM_008018525
- UniProtKB: A0A0D9RZA9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013948   ⟸   ENSCSAT00000016023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017928 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016023.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.930.40 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro PA_dom_sf UniProtKB/TrEMBL
  PA_domain UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
  Peptidase_M28B UniProtKB/TrEMBL
  TFR-like_dimer_dom_sf UniProtKB/TrEMBL
  TfR1/2_PA UniProtKB/TrEMBL
KEGG Report csab:103246724 UniProtKB/TrEMBL
NCBI Gene TFR2 ENTREZGENE
PANTHER PTHR10404 UniProtKB/TrEMBL
  TRANSFERRIN RECEPTOR PROTEIN 2 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
  PF02225 UniProtKB/TrEMBL
Superfamily-SCOP PA domain UniProtKB/TrEMBL
  SSF47672 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0D9RZA9 ENTREZGENE, UniProtKB/TrEMBL