KBTBD6 (kelch repeat and BTB domain containing 6) - Rat Genome Database

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Gene: KBTBD6 (kelch repeat and BTB domain containing 6) Chlorocebus sabaeus
Analyze
Symbol: KBTBD6
Name: kelch repeat and BTB domain containing 6
RGD ID: 18547272
Description: INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein K48-linked ubiquitination (ortholog); regulation of Rac protein signal transduction (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch repeat and BTB domain-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,388,132 - 19,391,857 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,389,455 - 19,391,482 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605724,844,640 - 24,849,745 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
KBTBD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,388,132 - 19,391,857 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,389,455 - 19,391,482 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605724,844,640 - 24,849,745 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KBTBD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381341,127,569 - 41,132,802 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1341,127,569 - 41,132,802 (-)EnsemblGRCh38hg38GRCh38
GRCh371341,701,705 - 41,706,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361340,599,709 - 40,604,936 (-)NCBINCBI36Build 36hg18NCBI36
Build 341340,599,708 - 40,604,936NCBI
Celera1322,759,139 - 22,764,364 (-)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1322,501,835 - 22,507,060 (-)NCBIHuRef
CHM1_11341,669,521 - 41,674,743 (-)NCBICHM1_1
T2T-CHM13v2.01340,346,698 - 40,351,926 (-)NCBIT2T-CHM13v2.0
Kbtbd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391479,689,275 - 79,692,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1479,689,275 - 79,692,258 (+)EnsemblGRCm39 Ensembl
GRCm381479,451,835 - 79,454,816 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1479,451,835 - 79,454,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv371479,851,642 - 79,854,623 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361478,185,990 - 78,188,971 (+)NCBIMGSCv36mm8
Celera1476,951,762 - 76,954,813 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1442.66NCBI
Kbtbd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,257,360 - 61,259,117 (+)NCBIGRCr8
mRatBN7.21554,848,285 - 54,850,042 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,848,446 - 54,850,453 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1558,981,738 - 58,983,495 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,100,130 - 60,101,887 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01556,925,008 - 56,926,765 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01561,731,574 - 61,733,331 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,731,735 - 61,733,742 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01565,395,106 - 65,396,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41561,501,576 - 61,503,070 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11561,517,355 - 61,518,847 (+)NCBI
Celera1554,430,259 - 54,432,016 (+)NCBICelera
Cytogenetic Map15q12NCBI
KBTBD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21440,644,847 - 40,650,291 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11331,748,565 - 31,754,007 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01322,329,845 - 22,335,301 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11340,918,892 - 40,924,098 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1340,921,761 - 40,923,813 (-)Ensemblpanpan1.1panPan2
KBTBD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,466,707 - 9,478,514 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,467,020 - 9,469,152 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,462,763 - 9,475,449 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0229,692,726 - 9,697,554 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,693,111 - 9,695,252 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,388,031 - 9,400,741 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,437,706 - 9,450,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,452,135 - 9,464,805 (+)NCBIUU_Cfam_GSD_1.0
LOC100154105
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1125,643,709 - 25,710,987 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11125,704,933 - 25,710,994 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21126,509,103 - 26,512,169 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 23 60
Low 13 20
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007960222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000018692   ⟹   ENSCSAP00000018135
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl319,389,455 - 19,391,482 (-)Ensembl
RefSeq Acc Id: XM_007960222   ⟹   XP_007958413
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1319,388,132 - 19,391,857 (-)NCBI
Vero_WHO_p1.0NW_02366605724,844,640 - 24,849,745 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007958413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018135.1
Reference Protein Sequences
RefSeq Acc Id: XP_007958413   ⟸   XM_007960222
RefSeq Acc Id: ENSCSAP00000018135   ⟸   ENSCSAT00000018692


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018601 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018692.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  KBTB_W-LIR UniProtKB/TrEMBL
  KBTBD6_7_BACK UniProtKB/TrEMBL
  KBTBD6_7_BTB_POZ UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report csab:103214330 UniProtKB/TrEMBL
NCBI Gene KBTBD6 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  KBTB_W-LIR UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A0D9SB96_CHLSB UniProtKB/TrEMBL