ARHGDIA (Rho GDP dissociation inhibitor alpha) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ARHGDIA (Rho GDP dissociation inhibitor alpha) Chlorocebus sabaeus
Analyze
Symbol: ARHGDIA
Name: Rho GDP dissociation inhibitor alpha
RGD ID: 18544000
Description: ENCODES a protein that exhibits fatty acid binding (ortholog); Hsp90 protein binding (ortholog); protein kinase binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); cellular response to organic cyclic compound (ortholog); cellular response to redox state (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); chronic kidney disease (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); immunological synapse (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GDP-dissociation inhibitor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,741,402 - 73,745,079 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,740,944 - 73,745,062 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,193,459 - 45,197,177 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGDIA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,741,402 - 73,745,079 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,740,944 - 73,745,062 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,193,459 - 45,197,177 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ARHGDIA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,867,721 - 81,871,337 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,867,721 - 81,871,378 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,825,597 - 79,829,213 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,418,886 - 77,422,527 (-)NCBINCBI36Build 36hg18NCBI36
Build 341777,418,886 - 77,422,527NCBI
Celera1776,429,063 - 76,432,256 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,227,385 - 75,230,633 (-)NCBIHuRef
CHM1_11779,911,833 - 79,915,499 (-)NCBICHM1_1
T2T-CHM13v2.01782,734,886 - 82,738,502 (-)NCBIT2T-CHM13v2.0
Arhgdia
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,468,925 - 120,472,450 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,468,930 - 120,472,450 (-)EnsemblGRCm39 Ensembl
GRCm3811120,578,099 - 120,581,624 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,578,104 - 120,581,624 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,438,549 - 120,442,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,394,202 - 120,397,337 (-)NCBIMGSCv36mm8
Celera11132,312,595 - 132,316,911 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.29NCBI
Arhgdia
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,352,858 - 106,356,347 (-)NCBIGRCr8
mRatBN7.210105,854,526 - 105,858,020 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,854,533 - 105,858,023 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,958,544 - 110,962,033 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,421,572 - 110,425,061 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,774,979 - 105,778,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,754,012 - 109,757,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,754,004 - 109,757,550 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,347,156 - 109,350,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,967,771 - 109,971,260NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10104,397,938 - 104,401,427 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Arhgdia
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,297,956 - 1,300,072 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,297,604 - 1,300,072 (+)NCBIChiLan1.0ChiLan1.0
ARHGDIA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,403,714 - 98,407,602 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,304,488 - 103,308,215 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,273,196 - 76,276,942 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11781,975,340 - 81,978,447 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1781,975,340 - 81,978,447 (-)Ensemblpanpan1.1panPan2
ARHGDIA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19419,350 - 422,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9419,413 - 423,252 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,021,510 - 1,024,385 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.091,012,711 - 1,015,586 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl91,012,165 - 1,078,415 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,037,876 - 1,040,773 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,164,453 - 1,167,349 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,243,370 - 1,246,265 (+)NCBIUU_Cfam_GSD_1.0
Arhgdia
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,025,305 - 1,027,650 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,383,380 - 5,386,494 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,383,370 - 5,386,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGDIA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,113,379 - 1,119,315 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,113,358 - 1,117,319 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Arhgdia
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,717,133 - 10,722,840 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,719,987 - 10,723,263 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 17 60
Low 3
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000000236   ⟹   ENSCSAP00000015817
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1673,740,944 - 73,745,062 (-)Ensembl
RefSeq Acc Id: XM_008013279   ⟹   XP_008011470
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,741,402 - 73,745,079 (-)NCBI
Vero_WHO_p1.0NW_02366607745,193,459 - 45,197,176 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008013280   ⟹   XP_008011471
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,741,402 - 73,744,598 (-)NCBI
Vero_WHO_p1.0NW_02366607745,193,459 - 45,196,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037993055   ⟹   XP_037848983
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,193,459 - 45,197,177 (-)NCBI
RefSeq Acc Id: XM_037993056   ⟹   XP_037848984
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,193,459 - 45,196,767 (-)NCBI
RefSeq Acc Id: XM_037993057   ⟹   XP_037848985
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,193,459 - 45,196,300 (-)NCBI
RefSeq Acc Id: XP_008011470   ⟸   XM_008013279
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008011471   ⟸   XM_008013280
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000015817   ⟸   ENSCSAT00000000236
RefSeq Acc Id: XP_037848983   ⟸   XM_037993055
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037848984   ⟸   XM_037993056
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037848985   ⟸   XM_037993057
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002218 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000236.1 UniProtKB/TrEMBL
Gene3D-CATH 2.70.50.30 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  Rho_GDI UniProtKB/TrEMBL
  RhoGDI_dom_sf UniProtKB/TrEMBL
NCBI Gene ARHGDIA ENTREZGENE
PANTHER PTHR10980 UniProtKB/TrEMBL
  RHO GDP-DISSOCIATION INHIBITOR 1 UniProtKB/TrEMBL
Pfam Rho_GDI UniProtKB/TrEMBL
PRINTS RHOGDI UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
UniProt A0A0D9S4M8_CHLSB UniProtKB/TrEMBL