ABCD3 (ATP binding cassette subfamily D member 3) - Rat Genome Database

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Gene: ABCD3 (ATP binding cassette subfamily D member 3) Chlorocebus sabaeus
Analyze
Symbol: ABCD3
Name: ATP binding cassette subfamily D member 3
RGD ID: 18468591
Description: ENCODES a protein that exhibits ATP binding (ortholog); fatty acyl-CoA hydrolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN bile acid and bile salt transport (ortholog); bile acid biosynthetic process (ortholog); fatty acid biosynthetic process (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); congenital bile acid synthesis defect 5 (ortholog); genetic disease (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); mitochondrion (ortholog); peroxisomal matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family D member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12038,750,147 - 38,846,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2038,748,787 - 38,845,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603379,200,937 - 79,302,556 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ABCD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12038,750,147 - 38,846,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2038,748,787 - 38,845,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603379,200,937 - 79,302,556 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ABCD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,385,131 - 94,518,663 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,418,389 - 94,518,666 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,883,945 - 94,984,219 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,656,599 - 94,756,672 (+)NCBINCBI36Build 36hg18NCBI36
Build 34194,596,031 - 94,696,105NCBI
Celera193,137,599 - 93,238,680 (+)NCBICelera
Cytogenetic Map1p21.3ENTREZGENE
HuRef193,005,619 - 93,105,917 (+)NCBIHuRef
CHM1_1194,998,783 - 95,099,070 (+)NCBICHM1_1
T2T-CHM13v2.0194,233,380 - 94,366,700 (+)NCBIT2T-CHM13v2.0
Abcd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393121,552,553 - 121,609,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3121,552,423 - 121,608,951 (-)EnsemblGRCm39 Ensembl
GRCm383121,758,904 - 121,815,302 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3121,758,774 - 121,815,302 (-)EnsemblGRCm38mm10GRCm38
MGSCv373121,461,828 - 121,518,133 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363121,750,933 - 121,807,238 (-)NCBIMGSCv36mm8
Celera3128,155,294 - 128,218,276 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map352.94NCBI
Abcd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82212,536,791 - 212,590,379 (-)NCBIGRCr8
mRatBN7.22209,852,087 - 209,905,763 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2209,852,087 - 209,906,020 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2217,515,099 - 217,568,654 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02215,422,840 - 215,476,397 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02210,264,674 - 210,318,230 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02225,335,708 - 225,389,120 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2225,335,718 - 225,389,120 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02243,374,189 - 243,409,604 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42218,396,071 - 218,432,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12218,359,132 - 218,395,230 (-)NCBI
Celera2202,282,471 - 202,317,962 (-)NCBICelera
RH 3.4 Map21501.0RGD
Cytogenetic Map2q42NCBI
Abcd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955423280,497 - 359,711 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955423280,497 - 359,711 (-)NCBIChiLan1.0ChiLan1.0
ABCD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21132,505,970 - 132,606,599 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11131,660,847 - 131,761,306 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,079,326 - 97,179,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1195,808,027 - 95,907,864 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl195,808,027 - 95,907,864 (+)Ensemblpanpan1.1panPan2
ABCD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1654,740,704 - 54,816,854 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl654,742,111 - 54,817,235 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha657,449,009 - 57,525,742 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0655,116,365 - 55,193,330 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl655,116,488 - 55,193,330 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1654,797,137 - 54,873,570 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0654,781,385 - 54,858,240 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0655,234,335 - 55,310,979 (-)NCBIUU_Cfam_GSD_1.0
Abcd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058104,201,915 - 104,288,290 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365374,659,484 - 4,746,616 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365374,659,685 - 4,745,992 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4122,847,927 - 122,953,257 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14122,847,925 - 122,929,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24134,491,144 - 134,572,292 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Abcd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247423,142,570 - 3,236,728 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247423,146,000 - 3,236,473 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 55
Low 1 20 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000017049   ⟹   ENSCSAP00000016541
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2038,748,787 - 38,845,989 (-)Ensembl
RefSeq Acc Id: XM_007977901   ⟹   XP_007976092
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12038,750,147 - 38,846,011 (-)NCBI
Vero_WHO_p1.0NW_02366603379,200,937 - 79,301,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038003236   ⟹   XP_037859164
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603379,200,937 - 79,302,556 (+)NCBI
RefSeq Acc Id: XM_038003238   ⟹   XP_037859166
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603379,245,438 - 79,302,556 (+)NCBI
RefSeq Acc Id: XM_038003241   ⟹   XP_037859169
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603379,245,443 - 79,301,890 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007976092 (Get FASTA)   NCBI Sequence Viewer  
  XP_037859164 (Get FASTA)   NCBI Sequence Viewer  
  XP_037859166 (Get FASTA)   NCBI Sequence Viewer  
  XP_037859169 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016541.1
Reference Protein Sequences
RefSeq Acc Id: XP_007976092   ⟸   XM_007977901
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S6Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000016541   ⟸   ENSCSAT00000017049
RefSeq Acc Id: XP_037859164   ⟸   XM_038003236
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S6Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859166   ⟸   XM_038003238
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S6Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859169   ⟸   XM_038003241
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S6Q2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001484 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017049.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  FA_transporter UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report csab:103224406 UniProtKB/TrEMBL
NCBI Gene ABCD3 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 UniProtKB/TrEMBL
  ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER UniProtKB/TrEMBL
Pfam ABC_membrane_2 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A0D9S6Q2 ENTREZGENE, UniProtKB/TrEMBL