ARHGAP17 (Rho GTPase activating protein 17) - Rat Genome Database

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Gene: ARHGAP17 (Rho GTPase activating protein 17) Chlorocebus sabaeus
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Symbol: ARHGAP17
Name: Rho GTPase activating protein 17
RGD ID: 18463257
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN actin filament organization (ortholog); calcium-ion regulated exocytosis (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1522,634,252 - 22,739,810 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl522,640,686 - 22,703,115 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660686,993,921 - 7,091,716 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGAP17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1522,634,252 - 22,739,810 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl522,640,686 - 22,703,115 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660686,993,921 - 7,091,716 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ARHGAP17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381624,919,389 - 25,015,369 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1624,919,389 - 25,015,666 (-)EnsemblGRCh38hg38GRCh38
GRCh371624,930,710 - 25,026,690 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361624,838,211 - 24,934,176 (-)NCBINCBI36Build 36hg18NCBI36
Build 341624,838,214 - 24,934,176NCBI
Celera1623,711,720 - 23,807,687 (-)NCBICelera
Cytogenetic Map16p12.1NCBI
HuRef1623,024,541 - 23,120,621 (-)NCBIHuRef
CHM1_11625,944,641 - 26,040,593 (-)NCBICHM1_1
T2T-CHM13v2.01625,199,011 - 25,294,991 (-)NCBIT2T-CHM13v2.0
Arhgap17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397122,878,372 - 122,969,171 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7122,878,441 - 122,969,138 (-)EnsemblGRCm39 Ensembl
GRCm387123,279,149 - 123,369,948 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7123,279,218 - 123,369,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv377130,422,663 - 130,513,429 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367123,070,419 - 123,161,030 (-)NCBIMGSCv36mm8
Celera7123,162,260 - 123,253,139 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map767.42NCBI
Arhgap17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81187,238,675 - 187,328,093 (-)NCBIGRCr8
mRatBN7.21177,807,579 - 177,897,027 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,807,583 - 177,896,854 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1186,143,532 - 186,232,738 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01193,329,522 - 193,418,726 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01186,007,252 - 186,096,430 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01193,239,036 - 193,328,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1193,239,040 - 193,328,371 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01200,297,800 - 200,387,169 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,145,313 - 182,234,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,285,231 - 182,375,315 (-)NCBI
Celera1175,495,700 - 175,585,527 (-)NCBICelera
Cytogenetic Map1q36NCBI
Arhgap17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554933,327,584 - 3,384,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554933,326,893 - 3,384,621 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21826,328,248 - 26,428,220 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11630,848,933 - 30,949,020 (-)NCBINHGRI_mPanPan1
PanPan1.11625,160,485 - 25,255,913 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1625,161,229 - 25,220,151 (-)Ensemblpanpan1.1panPan2
ARHGAP17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1621,081,965 - 21,176,685 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl621,073,912 - 21,176,205 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha626,076,872 - 26,171,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0621,222,691 - 21,315,817 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl621,222,712 - 21,311,972 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1621,025,615 - 21,120,189 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0620,928,650 - 21,023,425 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0621,323,131 - 21,417,935 (+)NCBIUU_Cfam_GSD_1.0
Arhgap17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344121,159,093 - 121,209,374 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365019,257,654 - 9,307,230 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365019,256,950 - 9,307,228 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP17
(Sus scrofa - pig)
No map positions available.
Arhgap17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247829,882,317 - 9,974,090 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247829,881,631 - 9,974,238 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20
Low 20 40
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000004527   ⟹   ENSCSAP00000002774
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl522,640,686 - 22,703,115 (-)Ensembl
RefSeq Acc Id: XM_007988160   ⟹   XP_007986351
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1522,642,138 - 22,739,810 (-)NCBI
Vero_WHO_p1.0NW_0236660686,993,922 - 7,091,716 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007988190   ⟹   XP_007986381
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1522,652,201 - 22,739,810 (-)NCBI
Vero_WHO_p1.0NW_0236660686,993,921 - 7,083,132 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007988200   ⟹   XP_007986391
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1522,642,144 - 22,739,810 (-)NCBI
Vero_WHO_p1.0NW_0236660686,993,922 - 7,091,711 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007988210   ⟹   XP_007986401
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1522,642,138 - 22,739,810 (-)NCBI
Vero_WHO_p1.0NW_0236660686,993,922 - 7,091,716 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037989734   ⟹   XP_037845662
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660686,993,922 - 7,089,763 (+)NCBI
RefSeq Acc Id: XM_037989735   ⟹   XP_037845663
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660686,993,922 - 7,089,763 (+)NCBI
RefSeq Acc Id: XP_007986401   ⟸   XM_007988210
- Peptide Label: isoform X4
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986351   ⟸   XM_007988160
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986391   ⟸   XM_007988200
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007986381   ⟸   XM_007988190
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000002774   ⟸   ENSCSAT00000004527
RefSeq Acc Id: XP_037845662   ⟸   XM_037989734
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037845663   ⟸   XM_037989735
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R2D5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006486 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004527.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  BAR_dom UniProtKB/TrEMBL
  RHG17/44/SH3BP1-like UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene ARHGAP17 ENTREZGENE
PANTHER 3BP-1 RELATED RHOGAP UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 17 UniProtKB/TrEMBL
Pfam BAR UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PROSITE BAR UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART BAR UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt A0A0D9R2D5 ENTREZGENE, UniProtKB/TrEMBL