ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5) - Rat Genome Database

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Gene: ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5) Chlorocebus sabaeus
Analyze
Symbol: ST3GAL5
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5
RGD ID: 18441560
Description: ENCODES a protein that exhibits lactosylceramide alpha-2,3-sialyltransferase activity (inferred); sialyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN protein glycosylation (inferred); ASSOCIATED WITH CD8 Deficiency, Familial (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lactosylceramide alpha-2,3-sialyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,235,682 - 21,314,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,287,241 - 21,313,558 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,166,353 - 91,219,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ST3GAL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,235,682 - 21,314,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,287,241 - 21,313,558 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,166,353 - 91,219,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ST3GAL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38285,837,120 - 85,889,034 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl285,837,120 - 85,905,199 (-)EnsemblGRCh38hg38GRCh38
GRCh37286,064,243 - 86,116,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,919,782 - 85,969,668 (-)NCBINCBI36Build 36hg18NCBI36
Build 34285,977,928 - 86,027,795NCBI
Celera285,894,364 - 85,944,312 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef285,963,652 - 86,013,554 (-)NCBIHuRef
CHM1_1285,995,811 - 86,045,674 (-)NCBICHM1_1
T2T-CHM13v2.0285,839,198 - 85,891,111 (-)NCBIT2T-CHM13v2.0
St3gal5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,074,555 - 72,131,555 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl672,074,576 - 72,131,555 (+)EnsemblGRCm39 Ensembl
GRCm38672,097,552 - 72,154,571 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,097,592 - 72,154,571 (+)EnsemblGRCm38mm10GRCm38
MGSCv37672,047,607 - 72,104,564 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36672,027,122 - 72,084,079 (+)NCBIMGSCv36mm8
Celera674,186,058 - 74,242,678 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.24NCBI
St3gal5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,692,840 - 105,750,774 (+)NCBIGRCr8
mRatBN7.24104,134,613 - 104,192,558 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4104,134,613 - 104,192,558 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,515,323 - 109,573,056 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,290,437 - 105,348,173 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,904,491 - 103,962,253 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,937,499 - 99,999,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,937,558 - 99,999,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04164,713,194 - 164,769,525 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,373,385 - 105,432,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14105,618,018 - 105,676,673 (+)NCBI
Celera493,289,811 - 93,346,557 (+)NCBICelera
Cytogenetic Map4q32NCBI
St3gal5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,692,182 - 1,732,595 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554241,692,182 - 1,729,206 (+)NCBIChiLan1.0ChiLan1.0
ST3GAL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21240,480,051 - 40,546,548 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A40,482,804 - 40,549,310 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A85,888,895 - 85,938,944 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A87,437,873 - 87,485,660 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,437,874 - 87,503,625 (-)Ensemblpanpan1.1panPan2
ST3GAL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11739,154,408 - 39,205,661 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1739,153,469 - 39,204,873 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,839,485 - 38,890,646 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,888,484 - 39,939,963 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,888,415 - 39,939,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11739,055,842 - 39,107,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01739,091,990 - 39,143,194 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01739,478,527 - 39,530,011 (+)NCBIUU_Cfam_GSD_1.0
St3gal5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,362,332 - 79,399,787 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,482,002 - 1,499,064 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,458,637 - 1,496,118 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST3GAL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl358,862,987 - 58,919,552 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1358,862,984 - 58,919,554 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2361,761,954 - 61,767,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
St3gal5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474917,312,152 - 17,355,578 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474917,312,144 - 17,354,906 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 11 60
Low 9
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014335   ⟹   ENSCSAP00000012311
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1421,287,241 - 21,313,558 (+)Ensembl
RefSeq Acc Id: XM_007969996   ⟹   XP_007968187
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11421,261,512 - 21,314,541 (+)NCBI
Vero_WHO_p1.0NW_02366604591,166,353 - 91,219,731 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038007202   ⟹   XP_037863130
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604591,166,353 - 91,219,731 (-)NCBI
RefSeq Acc Id: XM_038007203   ⟹   XP_037863131
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604591,166,353 - 91,219,673 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007968187 (Get FASTA)   NCBI Sequence Viewer  
  XP_037863130 (Get FASTA)   NCBI Sequence Viewer  
  XP_037863131 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012311.1
Reference Protein Sequences
RefSeq Acc Id: XP_007968187   ⟸   XM_007969996
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RUM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012311   ⟸   ENSCSAT00000014335
RefSeq Acc Id: XP_037863130   ⟸   XM_038007202
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037863131   ⟸   XM_038007203
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016237 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014335.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/TrEMBL
KEGG Report csab:103219931 UniProtKB/TrEMBL
NCBI Gene ST3GAL5 ENTREZGENE
PANTHER LACTOSYLCERAMIDE ALPHA-2,3-SIALYLTRANSFERASE UniProtKB/TrEMBL
  SIALYLTRANSFERASE UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/TrEMBL
PIRSF Sialyl_trans UniProtKB/TrEMBL
UniProt A0A0D9RUM2 ENTREZGENE, UniProtKB/TrEMBL