LOC103248364 (caspase-1) - Rat Genome Database

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Gene: LOC103248364 (caspase-1) Chlorocebus sabaeus
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Symbol: LOC103248364 (Ensembl: CARD16)
Name: caspase-1 (Ensembl:caspase recruitment domain family member 16)
RGD ID: 18440244
Description: ENCODES a protein that exhibits CARD domain binding (ortholog); cysteine-type endopeptidase inhibitor activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of interleukin-1 beta production (ortholog); negative regulation of lipopolysaccharide-mediated signaling pathway (ortholog); ASSOCIATED WITH ataxia telangiectasia (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); intellectual disability (ortholog); FOUND IN protease inhibitor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CARD16; caspase recruitment domain family member 16; caspase recruitment domain-containing protein 16
RGD Orthologs
Human
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,407,252 - 96,410,894 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,406,104 - 96,410,456 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236679616,988 - 10,178 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC103248364
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,407,252 - 96,410,894 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,406,104 - 96,410,456 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236679616,988 - 10,178 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CARD16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811105,041,563 - 105,045,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11105,041,326 - 105,101,431 (-)EnsemblGRCh38hg38GRCh38
GRCh3711104,912,290 - 104,916,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611104,417,263 - 104,421,261 (-)NCBINCBI36Build 36hg18NCBI36
Celera11102,076,226 - 102,080,224 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11100,843,050 - 100,847,048 (-)NCBIHuRef
CHM1_111104,794,992 - 104,798,990 (-)NCBICHM1_1
T2T-CHM13v2.011105,045,653 - 105,049,425 (-)NCBIT2T-CHM13v2.0
CARD16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29105,829,351 - 105,836,580 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111106,919,950 - 106,924,891 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01199,981,854 - 99,985,839 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl11103,467,368 - 103,468,288 (-)Ensemblpanpan1.1panPan2


Expression


Sequence


RefSeq Acc Id: ENSCSAT00000001096   ⟹   ENSCSAP00000014972
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl196,406,104 - 96,410,456 (-)Ensembl
RefSeq Acc Id: XM_037996245   ⟹   XP_037852173
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236679616,988 - 10,178 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037852173 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014972.1
RefSeq Acc Id: XP_037852173   ⟸   XM_037996245
RefSeq Acc Id: ENSCSAP00000014972   ⟸   ENSCSAT00000001096


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003066 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001096.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
InterPro CARD UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
NCBI Gene CARD16 ENTREZGENE
PANTHER CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 UniProtKB/TrEMBL
  CASPASE-1 UniProtKB/TrEMBL
Pfam CARD UniProtKB/TrEMBL
PROSITE CARD UniProtKB/TrEMBL
Superfamily-SCOP DEATH domain UniProtKB/TrEMBL
UniProt A0A0D9S283_CHLSB UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103248364  caspase-1  CARD16  caspase recruitment domain family member 16  Symbol and/or name change 5135510 APPROVED