DCTN5 (dynactin subunit 5) - Rat Genome Database

Name: DCTN5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: DCTN5 (dynactin subunit 5) Chlorocebus sabaeus

Analyze

Symbol:

DCTN5

Name:

dynactin subunit 5

RGD ID:

18438936

Description:

INVOLVED IN aorta development (ortholog); coronary vasculature development (ortholog); ventricular septum development (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); nuclear membrane (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC103229803

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DCTN5 (dynactin subunit 5)	NCBI	Ortholog
Mus musculus (house mouse):	Dctn5 (dynactin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Dctn5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dctn5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DCTN5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DCTN5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dctn5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DCTN5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dctn5 (dynactin subunit 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	21,358,483 - 21,386,128 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	21,358,584 - 21,384,845 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	8,404,656 - 8,438,786 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Cancer, Familial (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aorta development (ISO)

coronary vasculature development (ISO)

ventricular septum development (ISO)

Cellular Component

centrosome (ISO)

dynactin complex (IEA)

nuclear membrane (ISO)

nucleoplasm (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondria transport pathway (ISO)

References

Genomics

Comparative Map Data

DCTN5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	21,358,483 - 21,386,128 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	21,358,584 - 21,384,845 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	8,404,656 - 8,438,786 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

DCTN5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	23,641,466 - 23,677,472 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	23,641,466 - 23,677,472 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	23,652,787 - 23,688,793 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	23,560,308 - 23,588,683 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	22,430,985 - 22,459,355 (+)	NCBI		Celera
Cytogenetic Map	16	p12.2	NCBI
HuRef	16	21,742,321 - 21,774,697 (+)	NCBI		HuRef
CHM1_1	16	24,664,415 - 24,696,788 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	23,917,274 - 23,953,274 (+)	NCBI		T2T-CHM13v2.0

Dctn5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	121,732,264 - 121,748,267 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	121,732,264 - 121,748,267 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	122,133,041 - 122,149,044 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	122,133,041 - 122,149,044 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	129,276,555 - 129,292,558 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	121,924,220 - 121,940,192 (+)	NCBI		MGSCv36	mm8
Celera	7	122,023,279 - 122,039,287 (+)	NCBI		Celera
Cytogenetic Map	7	F2	NCBI
cM Map	7	65.47	NCBI

Dctn5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	186,120,415 - 186,137,146 (+)	NCBI		GRCr8
mRatBN7.2	1	176,689,176 - 176,705,907 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	176,689,156 - 176,705,906 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	185,017,122 - 185,033,882 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	192,203,078 - 192,219,838 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	184,887,036 - 184,903,835 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	192,088,709 - 192,105,421 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	192,088,672 - 192,105,429 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	199,151,318 - 199,167,998 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	180,952,836 - 180,969,511 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	181,092,747 - 181,108,620 (+)	NCBI
Celera	1	174,398,964 - 174,415,608 (+)	NCBI		Celera
Cytogenetic Map	1	q36	NCBI

Dctn5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	2,175,585 - 2,192,039 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	2,175,585 - 2,204,742 (+)	NCBI	ChiLan1.0	ChiLan1.0

DCTN5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	25,051,801 - 25,080,616 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	29,571,267 - 29,600,075 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	14,431,114 - 14,470,264 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	23,892,126 - 23,920,446 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	23,892,126 - 23,920,446 (+)	Ensembl	panpan1.1		panPan2

DCTN5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	22,188,511 - 22,209,590 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	22,189,040 - 22,209,596 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	23,754,694 - 23,776,369 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	22,331,732 - 22,353,439 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	22,331,740 - 22,353,425 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	22,135,770 - 22,156,752 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	22,037,431 - 22,059,343 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	22,433,371 - 22,454,423 (-)	NCBI		UU_Cfam_GSD_1.0

Dctn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	120,175,573 - 120,211,920 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	8,272,765 - 8,312,977 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	8,273,381 - 8,309,780 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DCTN5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	22,558,951 - 22,586,802 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	22,564,173 - 22,586,806 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	4,558 - 17,215 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Dctn5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	8,781,062 - 8,796,164 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	8,781,016 - 8,797,084 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	18	60
Low		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007988057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005237698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000004780 ⟹ ENSCSAP00000003027

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	5	21,358,584 - 21,384,845 (+)	Ensembl

RefSeq Acc Id:

XM_007988057 ⟹ XP_007986248

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	5	21,358,483 - 21,386,128 (+)	NCBI
Vero_WHO_p1.0	NW_023666068	8,408,215 - 8,438,786 (-)	NCBI

Sequence:

show sequence

TAGAGCGGAAGTAGAGGAGCGGCCGGAAGTAGCCGGAACCTCAGAAAGACTGACCGACTGACTC
TGACAGGATCCGGGCCTGAGGGAAGGAGGCGGCGGCCATGGAGTTGGGCGAGCTGCTCTACAAC
AAGTCCGAGTACATCGAGACGGCATCTGGGAACAAAGTCAGTCGCCAGTCAGTGTTGTGTGGAA
GCCAGAACATCGTTCTCAATGGCAAGACCATCGTGATGAATGACTGTATTATCCGAGGGGATCT
GGCAAACGTAAGAGTTGGACGTCATTGTGTTGTAAAAAGTCGTAGTGTCATAAGGCCACCATTC
AAGAAATTCAGCAAAGGTGTTGCATTCTTTCCTTTACATATTGGGGACCATGTCTTTATTGAGG
AAGATTGTGTGGTCAACGCAGCTCAGATTGGTTCCTACGTTCATGTTGGGAAGAACTGTGTGAT
TGGGCGCCGATGTGTGTTGAAAGACTGCTGCAAAATTCTTGACAACACAGTATTACCTCCAGAA
ACTGTGGTCCCACCATTCACTGTCTTCTCAGGCTGCCCAGGACTCTTCTCAGGGGAGCTCCCGG
AGTGCACTCAGGAGCTGATGATTGACGTCACCAAGAGCTACTACCAGAAGTTTTTGCCGCTGAC
ACAAGTCTAGCATCTCTGCCTCATGTCTTGAATCTGCTTGAGCTCTAAGATGAACCTGAGGACA
AAGTGAGCCAGTCAGCACCTAGAAAAAACTCTCTTGTCTTTGACATCTACCACCCTCCTCCTTT
TAAAAAATTTCTTTAGAATTTCTCAATCCTCAAGGCTCTAACCTCTTAAGAATTTACTAACAGA
CAGACTATCTGGAGGAGTTATCTTCAAATGCTGTGCTTACACCTTATCTGTGAACAGTCACTTT
GTACCATTATCTGTGGAACACAGAATCATCTGTTCCCAACGCTCCAGCCCCTTGGTCCTGTGGA
TGGCTGGATCCTGCCTGAAACGGACCTGCAGAGCAGCAGCACCCTTCCGGTGTGGAGGCTGTGT
AGCTGGTGTGCTGCTCACGGCCATACACTACCCATGCTGAGAGCCTCTCACACAGGTAATGCCC
AGCTTTGCTGCTGCTAACACATTTGGCCAGTTGTTGGCAATTGTTCATAACCCTGGGAAAGGTG
TTTGTGACTTTTCAGAGCCCAGATTCCTGTTGGCTCTTAAAACTTGAGGGTAGGGGTGATTAGT
GTTTCTCTCTTTCCTTCCCAAAATGACCTTAGCTGTCCTAGGGTAGTGAGTAAAAGACTTTTTA
GCATTTTGACCTGGGGCCTTTGGCTTTCACTAAAAGTGGGGACCTCAGCATCCCAGATTGTAAT
TTTGCCAAGTGTTAGATTTGAGTCTCTCATGTGAAGGCATTAGGCAGTTACTGCTTGCCTCAAG
GTACTTACCTTATTTCATTGAAGACACCACATTTGTGAACTCTTGCTCCCTGGCCTAGAACCAT
TCAACCCACCCTGTATTTGCTATAAACTCCACAATTCACACCAAAATGTCTGTACTCAGAGTCC
ATTCGCATATATACATGAAGGGCTCGTAAAATCAGTTTGTGGGCACAGAGCCCCAGGAGTAAAT
GAAGTTGCTAGGGCTGTTCTTACCATCTCCTTCTGACCAGATAGCACAATCTTTCCTGGTTCTG
CTCTGACCTCTTAGCTTAGAAAGAAGATTTAGAAGTTAGAGGCTAAGCAGGTTGTCCTTGCTTA
ATGCTCTGATCCATAAGTGAATAGCCCAGAACAGTTCAGTCTTGAAGATTAGAATTTAGCAAGA
GCTATCCTGACTTAATATCCAGTTGCGGGGGTTGCAAAACAGAATAGCTGTATGTAATCATTGC
CACTAGTTCCATCTAGAACTCCTTTCTAGCTTGTCATTTTTTAAATGTTTATACATTAAAACCA
CCAAAATAAA

hide sequence

RefSeq Acc Id:

XR_005237698

Type:

NON-CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666068	8,404,656 - 8,438,786 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_007986248	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000003027
	ENSCSAP00000003027.1

RefSeq Acc Id:	XP_007986248 ⟸ XM_007988057
- UniProtKB:	A0A0D9R338 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000003027 ⟸ ENSCSAT00000004780

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006743	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004780.1	UniProtKB/TrEMBL
Gene3D-CATH	Hexapeptide repeat proteins	UniProtKB/TrEMBL
InterPro	DCTN5	UniProtKB/TrEMBL
	Trimer_LpxA-like_sf	UniProtKB/TrEMBL
KEGG Report	csab:103229803	UniProtKB/TrEMBL
NCBI Gene	LOC103229803	ENTREZGENE
PANTHER	DYNACTIN SUBUNIT 5	UniProtKB/TrEMBL
	DYNACTIN SUBUNIT 5	UniProtKB/TrEMBL
Pfam	DCTN5	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51161	UniProtKB/TrEMBL
UniProt	A0A0D9R338	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-12-08	DCTN5	dynactin subunit 5	LOC103229803	dynactin subunit 5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations