ZBTB3 (zinc finger and BTB domain containing 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ZBTB3 (zinc finger and BTB domain containing 3) Chlorocebus sabaeus
Analyze
Symbol: ZBTB3
Name: zinc finger and BTB domain containing 3
RGD ID: 18415634
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH intellectual disability (ortholog); leukocyte adhesion deficiency 3 (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger and BTB domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,157,966 - 11,160,582 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,158,409 - 11,164,749 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,495,904 - 108,498,227 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZBTB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,157,966 - 11,160,582 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,158,409 - 11,164,749 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,495,904 - 108,498,227 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ZBTB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,750,963 - 62,754,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,748,319 - 62,754,184 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,518,435 - 62,521,632 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,275,011 - 62,278,190 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,275,012 - 62,278,190NCBI
Celera1159,847,033 - 59,850,254 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,847,138 - 58,850,359 (-)NCBIHuRef
CHM1_11162,401,497 - 62,404,718 (-)NCBICHM1_1
T2T-CHM13v2.01162,740,349 - 62,743,546 (-)NCBIT2T-CHM13v2.0
Zbtb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,779,853 - 8,783,035 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,779,919 - 8,782,210 (+)EnsemblGRCm39 Ensembl
GRCm38198,802,489 - 8,804,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,802,555 - 8,804,846 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,876,986 - 8,879,344 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,869,557 - 8,871,899 (+)NCBIMGSCv36mm8
Celera198,562,342 - 8,564,700 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.65NCBI
Zbtb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,125,200 - 215,127,517 (+)NCBIGRCr8
mRatBN7.21205,693,906 - 205,703,277 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,686,620 - 205,704,515 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,104,495 - 214,106,812 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,139,628 - 221,141,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,832,331 - 213,834,648 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,998,092 - 225,002,951 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,998,172 - 225,000,489 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,924,096 - 231,938,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,469,242 - 211,471,559 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1203,209,010 - 203,211,327 (+)NCBICelera
Cytogenetic Map1q43NCBI
Zbtb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599475,673 - 477,232 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599472,135 - 477,403 (+)NCBIChiLan1.0ChiLan1.0
ZBTB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,973,380 - 63,983,394 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,016,082 - 65,026,097 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,106,299 - 58,114,230 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,460,128 - 61,467,417 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,460,128 - 61,462,398 (-)Ensemblpanpan1.1panPan2
ZBTB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,924,158 - 53,926,505 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,924,687 - 53,926,228 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,529,931 - 52,532,308 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01854,976,638 - 54,979,015 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,977,199 - 54,978,740 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,072,994 - 54,075,371 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,647,490 - 53,649,867 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,443,770 - 54,446,147 (+)NCBIUU_Cfam_GSD_1.0
Zbtb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,419,663 - 10,422,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581533,449 - 535,781 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581533,418 - 535,789 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZBTB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.129,017,560 - 9,021,244 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,363,510 - 8,365,871 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Zbtb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,224,320 - 1,225,867 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,223,769 - 1,226,891 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 20 60
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004755   ⟹   ENSCSAP00000003000
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl111,158,409 - 11,164,749 (+)Ensembl
RefSeq Acc Id: XM_007995229   ⟹   XP_007993420
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1111,157,966 - 11,160,582 (+)NCBI
Vero_WHO_p1.0NW_023666038108,495,904 - 108,498,227 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037999185   ⟹   XP_037855113
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666038108,495,918 - 108,498,227 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007993420 (Get FASTA)   NCBI Sequence Viewer  
  XP_037855113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000003000
  ENSCSAP00000003000.1
Reference Protein Sequences
RefSeq Acc Id: XP_007993420   ⟸   XM_007995229
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R311 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003000   ⟸   ENSCSAT00000004755
RefSeq Acc Id: XP_037855113   ⟸   XM_037999185
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006712 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004755.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report csab:103233898 UniProtKB/TrEMBL
NCBI Gene ZBTB3 ENTREZGENE
PANTHER GM08392P UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0D9R311 ENTREZGENE, UniProtKB/TrEMBL