AGXT2 (alanine--glyoxylate aminotransferase 2) - Rat Genome Database

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Gene: AGXT2 (alanine--glyoxylate aminotransferase 2) Chlorocebus sabaeus
Analyze
Symbol: AGXT2
Name: alanine--glyoxylate aminotransferase 2
RGD ID: 18403965
Description: ENCODES a protein that exhibits beta-alanine-pyruvate transaminase activity (ortholog); INVOLVED IN N(omega),N(omega)-dimethyl-L-arginine catabolic process (ortholog); ASSOCIATED WITH alpha-methylacyl-CoA racemase deficiency (ortholog); atrial fibrillation (ortholog); Beta-Aminoisobutyric Acid, Urinary Excretion of (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alanine--glyoxylate aminotransferase 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1433,889,615 - 33,933,500 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl433,888,533 - 33,933,449 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607124,192,128 - 24,237,014 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AGXT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1433,889,615 - 33,933,500 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl433,888,533 - 33,933,449 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607124,192,128 - 24,237,014 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
AGXT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38534,998,102 - 35,047,949 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl534,998,101 - 35,048,135 (-)EnsemblGRCh38hg38GRCh38
GRCh37534,998,207 - 35,048,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36535,033,963 - 35,083,756 (-)NCBINCBI36Build 36hg18NCBI36
Build 34535,033,962 - 35,083,756NCBI
Celera534,880,411 - 34,930,420 (-)NCBICelera
Cytogenetic Map5p13.2NCBI
HuRef534,946,958 - 34,996,974 (-)NCBIHuRef
CHM1_1535,000,510 - 35,050,560 (-)NCBICHM1_1
T2T-CHM13v2.0535,245,145 - 35,294,998 (-)NCBIT2T-CHM13v2.0
Agxt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391510,358,602 - 10,410,244 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1510,358,618 - 10,410,239 (+)EnsemblGRCm39 Ensembl
GRCm381510,358,516 - 10,410,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1510,358,532 - 10,410,153 (+)EnsemblGRCm38mm10GRCm38
MGSCv371510,288,334 - 10,339,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361510,303,304 - 10,354,463 (+)NCBIMGSCv36mm8
Celera1510,155,885 - 10,206,282 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.35NCBI
Agxt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8261,063,416 - 61,104,828 (+)NCBIGRCr8
mRatBN7.2259,336,252 - 59,377,664 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl259,336,283 - 59,377,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx266,436,973 - 66,485,549 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0264,558,502 - 64,607,076 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0259,559,851 - 59,608,437 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0260,337,667 - 60,379,144 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl260,337,667 - 60,379,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0284,308,289 - 84,348,843 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4259,713,365 - 59,754,876 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1259,641,628 - 59,683,371 (+)NCBI
Celera259,294,201 - 59,335,576 (-)NCBICelera
Cytogenetic Map2q16NCBI
Agxt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542620,101,620 - 20,142,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542620,102,368 - 20,142,596 (-)NCBIChiLan1.0ChiLan1.0
AGXT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2475,288,478 - 75,339,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1573,442,171 - 73,493,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0575,322,351 - 75,373,261 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1580,601,554 - 80,652,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl580,601,554 - 80,652,575 (+)Ensemblpanpan1.1panPan2
AGXT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1473,292,117 - 73,327,769 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl473,292,101 - 73,327,962 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha472,908,514 - 72,944,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0473,797,662 - 73,833,439 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl473,797,685 - 73,833,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1473,545,393 - 73,581,098 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0473,668,622 - 73,704,659 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0474,202,253 - 74,237,942 (+)NCBIUU_Cfam_GSD_1.0
Agxt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213224,827,079 - 224,863,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365186,508,928 - 6,544,146 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365186,508,928 - 6,544,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGXT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1620,576,659 - 20,617,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11620,576,661 - 20,617,008 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21621,478,686 - 21,519,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Agxt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475919,858,148 - 19,938,229 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475919,858,255 - 19,909,516 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 16 16 12
Below cutoff 20 2 34

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015204   ⟹   ENSCSAP00000013149
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl433,888,533 - 33,933,449 (-)Ensembl
RefSeq Acc Id: XM_037990744   ⟹   XP_037846672
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607124,192,128 - 24,237,014 (-)NCBI
RefSeq Acc Id: XM_037990745   ⟹   XP_037846673
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607124,192,128 - 24,237,014 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037846672 (Get FASTA)   NCBI Sequence Viewer  
  XP_037846673 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013149.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000013149   ⟸   ENSCSAT00000015204
RefSeq Acc Id: XP_037846673   ⟸   XM_037990745
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RX10 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037846672   ⟸   XM_037990744
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RX10 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017109 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015204.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro Aminotrans_3 UniProtKB/TrEMBL
  Aminotrans_3_PPA_site UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
KEGG Report csab:103215117 UniProtKB/TrEMBL
NCBI Gene AGXT2 ENTREZGENE
PANTHER ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR45688 UniProtKB/TrEMBL
Pfam Aminotran_3 UniProtKB/TrEMBL
PIRSF Transaminase_4ab_Lys_Orn UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt A0A0D9RX10 ENTREZGENE, UniProtKB/TrEMBL