SEPTIN6 (septin 6) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SEPTIN6 (septin 6) Chlorocebus sabaeus
Analyze
Symbol: SEPTIN6
Name: septin 6
RGD ID: 18401024
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); molecular adaptor activity (inferred); INVOLVED IN cilium assembly (inferred); cytoskeleton-dependent cytokinesis (inferred); ASSOCIATED WITH autistic disorder (ortholog); syndromic X-linked intellectual disability 14 (ortholog); syndromic X-linked intellectual disability Cabezas type (ortholog); FOUND IN axon terminus (ortholog); cleavage furrow (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEPT6; septin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SEPTIN6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SEPTIN6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X119,615,724 - 119,693,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX119,615,724 - 119,693,370 (-)EnsemblGRCh38hg38GRCh38
GRCh37X118,749,687 - 118,827,131 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,633,715 - 118,711,361 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X118,531,571 - 118,609,215NCBI
CeleraX119,204,389 - 119,281,983 (-)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX108,243,227 - 108,320,808 (-)NCBIHuRef
CHM1_1X118,661,311 - 118,738,951 (-)NCBICHM1_1
T2T-CHM13v2.0X117,993,452 - 118,071,836 (-)NCBIT2T-CHM13v2.0
Septin6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X36,174,925 - 36,253,711 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX36,174,979 - 36,255,447 (-)EnsemblGRCm39 Ensembl
GRCm38X36,911,272 - 36,990,036 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX36,911,326 - 36,991,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X34,451,267 - 34,529,690 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X33,343,690 - 33,420,902 (-)NCBIMGSCv36mm8
CeleraX23,634,917 - 23,713,330 (-)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX21.32NCBI
Septin6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,018,951 - 121,157,677 (-)NCBIGRCr8
mRatBN7.2X116,153,255 - 116,230,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX116,153,255 - 116,230,115 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX118,260,460 - 118,333,344 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,829,599 - 121,902,491 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X119,375,754 - 119,448,595 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X123,524,954 - 123,601,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,524,950 - 123,662,350 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X123,669,895 - 123,746,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X7,871,020 - 7,949,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX115,386,688 - 115,458,210 (-)NCBICelera
Cytogenetic MapXq34NCBI
Septin6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955534305,865 - 382,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955534306,691 - 381,799 (+)NCBIChiLan1.0ChiLan1.0
SEPTIN6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X118,997,307 - 119,075,309 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X119,000,910 - 119,078,834 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X108,648,294 - 108,726,196 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X119,074,291 - 119,152,830 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX119,074,291 - 119,152,830 (-)Ensemblpanpan1.1panPan2
SEPTIN6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X91,647,293 - 91,714,379 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX91,647,969 - 91,714,164 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX77,722,082 - 77,789,109 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X93,386,421 - 93,453,554 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX93,386,425 - 93,454,230 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X90,839,093 - 90,906,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X92,597,841 - 92,664,953 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X92,327,013 - 92,394,128 (-)NCBIUU_Cfam_GSD_1.0
Septin6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X90,682,172 - 90,754,460 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647910,233,005 - 10,305,392 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647910,233,035 - 10,305,327 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX98,031,890 - 98,161,607 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X98,033,212 - 98,106,082 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,558,623 - 113,631,613 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Septin6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248953,582,538 - 3,650,010 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248953,583,198 - 3,649,478 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 31 20 38
Low 5 22
Below cutoff

Sequence


RefSeq Acc Id: XM_008019423   ⟹   XP_008017614
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019424   ⟹   XP_008017615
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019425   ⟹   XP_008017616
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019426   ⟹   XP_008017617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019428   ⟹   XP_008017619
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,372,354 - 32,449,079 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008019429   ⟹   XP_008017620
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606532,369,118 - 32,449,079 (-)NCBI
Sequence:
RefSeq Acc Id: XP_008017614   ⟸   XM_008019423
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008017615   ⟸   XM_008019424
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008017620   ⟸   XM_008019429
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S0H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008017617   ⟸   XM_008019426
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S0H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008017616   ⟸   XM_008019425
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008017619   ⟸   XM_008019428
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S0H0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018351 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016451.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
NCBI Gene SEPTIN6 ENTREZGENE
PANTHER PTHR18884:SF55 UniProtKB/TrEMBL
  SEPTIN UniProtKB/TrEMBL
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0D9S0H0 ENTREZGENE, UniProtKB/TrEMBL