TAOK2 (TAO kinase 2) - Rat Genome Database

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Gene: TAOK2 (TAO kinase 2) Chlorocebus sabaeus
Analyze
Symbol: TAOK2
Name: TAO kinase 2
RGD ID: 18399066
Description: ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase kinase activity (ortholog); INVOLVED IN MAPK cascade (ortholog); regulation of postsynapse organization (ortholog); regulation of synaptic membrane adhesion (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103231894; serine/threonine-protein kinase TAO2; uncharacterized LOC103231894; uncharacterized protein LOC103231894
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,669,687 - 26,688,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,669,702 - 26,688,389 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,844,898 - 2,863,744 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TAOK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,669,687 - 26,688,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,669,702 - 26,688,389 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,844,898 - 2,863,744 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TAOK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381629,973,868 - 29,992,261 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1629,973,868 - 29,992,261 (+)EnsemblGRCh38hg38GRCh38
GRCh371629,985,189 - 30,003,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361629,892,723 - 29,911,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 341629,892,722 - 29,907,220NCBI
Celera1672,792,142 - 72,810,504 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,646,198 - 27,664,595 (+)NCBIHuRef
CHM1_11631,200,977 - 31,219,371 (+)NCBICHM1_1
T2T-CHM13v2.01630,256,503 - 30,274,899 (+)NCBIT2T-CHM13v2.0
Taok2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,464,848 - 126,485,468 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,464,850 - 126,483,875 (-)EnsemblGRCm39 Ensembl
GRCm387126,865,674 - 126,886,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,865,678 - 126,884,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,009,191 - 134,028,481 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera7126,713,815 - 126,733,105 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
Taok2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,906,236 - 190,925,359 (-)NCBIGRCr8
mRatBN7.21181,475,708 - 181,494,738 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,475,711 - 181,494,613 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,830,945 - 189,845,358 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,017,020 - 197,031,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,684,241 - 189,698,650 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,301,789 - 198,354,601 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,301,938 - 198,320,075 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,281,965 - 205,302,445 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,049,010 - 186,063,423 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,198,900 - 186,213,304 (-)NCBI
Celera1179,134,902 - 179,149,315 (-)NCBICelera
Cytogenetic Map1q36NCBI
Taok2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,969,096 - 6,985,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,968,537 - 6,986,608 (-)NCBIChiLan1.0ChiLan1.0
TAOK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,723,431 - 30,742,044 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,483,871 - 35,502,484 (-)NCBINHGRI_mPanPan1
PanPan1.11630,347,229 - 30,365,647 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,347,229 - 30,366,743 (+)Ensemblpanpan1.1panPan2
TAOK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,014,685 - 18,029,188 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,000,138 - 18,029,185 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,587,820 - 19,606,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,144,778 - 18,163,340 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,092,584 - 18,163,339 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,944,193 - 17,962,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,859,369 - 17,877,699 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,175,174 - 18,193,525 (+)NCBIUU_Cfam_GSD_1.0
Taok2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,379,172 - 124,397,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,477,032 - 12,495,501 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,477,032 - 12,495,298 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAOK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,177,737 - 18,198,085 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,178,347 - 18,198,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Taok2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,256,085 - 13,262,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla_female_1.0 EnsemblNW_00462478213,234,422 - 13,252,663 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,234,422 - 13,263,495 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 60
Low 18
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004177   ⟹   ENSCSAP00000002440
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl526,669,702 - 26,688,389 (-)Ensembl
RefSeq Acc Id: XM_007989649   ⟹   XP_007987840
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1526,673,596 - 26,688,418 (-)NCBI
Vero_WHO_p1.0NW_0236660682,844,898 - 2,859,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007989657   ⟹   XP_007987848
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1526,669,868 - 26,688,051 (-)NCBI
Vero_WHO_p1.0NW_0236660682,844,898 - 2,863,744 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005237688
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660682,844,898 - 2,862,708 (+)NCBI
RefSeq Acc Id: XR_005237689
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660682,844,898 - 2,862,707 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007987840 (Get FASTA)   NCBI Sequence Viewer  
  XP_007987848 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002440
  ENSCSAP00000002440.1
Reference Protein Sequences
RefSeq Acc Id: XP_007987848   ⟸   XM_007989657
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R1F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007987840   ⟸   XM_007989649
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000002440   ⟸   ENSCSAT00000004177


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006141 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004177.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene TAOK2 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TAO2 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0D9R1F1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 TAOK2  TAO kinase 2  LOC103231894  uncharacterized LOC103231894  Data merged from RGD:18499158 737654 PROVISIONAL