FBXO7 (F-box protein 7) - Rat Genome Database

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Gene: FBXO7 (F-box protein 7) Chlorocebus sabaeus
Analyze
Symbol: FBXO7
Name: F-box protein 7
RGD ID: 18366302
Description: ENCODES a protein that exhibits protein heterodimerization activity (inferred); protein kinase binding (inferred); ubiquitin binding (inferred); INVOLVED IN autophagy of mitochondrion (ortholog); lymphocyte differentiation (ortholog); negative regulation of G1/S transition of mitotic cell cycle (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH genetic disease (ortholog); Glucose-Galactose Malabsorption (ortholog); muscular dystrophy-dystroglycanopathy type B6 (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11915,300,135 - 15,324,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1915,300,158 - 15,323,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045110,683,150 - 110,707,342 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FBXO7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11915,300,135 - 15,324,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1915,300,158 - 15,323,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045110,683,150 - 110,707,342 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FBXO7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,474,811 - 32,498,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,474,676 - 32,498,829 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,870,798 - 32,894,816 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,200,707 - 31,224,818 (+)NCBINCBI36Build 36hg18NCBI36
Build 342231,195,263 - 31,219,369NCBI
Celera2216,672,879 - 16,696,990 (+)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2215,827,931 - 15,852,000 (+)NCBIHuRef
CHM1_12232,830,063 - 32,854,178 (+)NCBICHM1_1
T2T-CHM13v2.02232,938,705 - 32,962,724 (+)NCBIT2T-CHM13v2.0
Fbxo7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,856,313 - 85,887,737 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1085,857,836 - 85,887,737 (+)EnsemblGRCm39 Ensembl
GRCm381086,020,449 - 86,051,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,021,972 - 86,051,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371085,484,674 - 85,511,073 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361085,451,796 - 85,478,128 (+)NCBIMGSCv36mm8
Celera1087,995,701 - 88,022,106 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.91NCBI
Fbxo7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,696,951 - 19,725,180 (-)NCBIGRCr8
mRatBN7.2717,809,224 - 17,837,549 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,809,231 - 17,837,530 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx719,771,322 - 19,799,547 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,928,523 - 21,956,738 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,710,970 - 21,739,195 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,815,246 - 23,843,505 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,815,245 - 23,843,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0723,964,601 - 23,993,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,947,498 - 19,975,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1719,960,416 - 19,988,648 (-)NCBI
Celera715,042,489 - 15,070,722 (-)NCBICelera
Cytogenetic Map7q13NCBI
Fbxo7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540541,433,082 - 41,453,909 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540541,429,421 - 41,449,670 (+)NCBIChiLan1.0ChiLan1.0
FBXO7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22342,411,197 - 42,435,546 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12245,111,484 - 45,135,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02213,481,255 - 13,505,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12231,335,423 - 31,359,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2231,335,423 - 31,359,224 (+)Ensemblpanpan1.1panPan2
FBXO7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11030,928,059 - 30,948,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1030,928,329 - 30,948,977 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1030,910,928 - 30,931,963 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01031,770,136 - 31,791,111 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1031,770,138 - 31,791,130 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11031,510,102 - 31,530,961 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01031,799,411 - 31,820,248 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01031,985,722 - 32,006,997 (-)NCBIUU_Cfam_GSD_1.0
Fbxo7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494514,251,029 - 14,266,764 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364927,261,009 - 7,276,943 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364927,261,442 - 7,276,779 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl512,505,654 - 12,526,232 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1512,505,646 - 12,526,206 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2512,291,445 - 12,313,045 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Fbxo7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247501,977,761 - 1,997,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247501,977,666 - 1,997,408 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 60
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000006335   ⟹   ENSCSAP00000004541
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1915,300,158 - 15,323,956 (+)Ensembl
RefSeq Acc Id: XM_007975570   ⟹   XP_007973761
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11915,300,135 - 15,324,256 (+)NCBI
Vero_WHO_p1.0NW_023666045110,683,150 - 110,707,342 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007975571   ⟹   XP_007973762
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11915,300,653 - 15,324,256 (+)NCBI
Vero_WHO_p1.0NW_023666045110,683,150 - 110,706,781 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007975573   ⟹   XP_007973764
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11915,300,171 - 15,323,773 (+)NCBI
Vero_WHO_p1.0NW_023666045110,683,150 - 110,707,342 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007973761 (Get FASTA)   NCBI Sequence Viewer  
  XP_007973762 (Get FASTA)   NCBI Sequence Viewer  
  XP_007973764 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004541
  ENSCSAP00000004541.1
RefSeq Acc Id: XP_007973761   ⟸   XM_007975570
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R7F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007973764   ⟸   XM_007975573
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007973762   ⟸   XM_007975571
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000004541   ⟸   ENSCSAT00000006335


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008283 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006335.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.40.1000.30 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  Fbxo7 UniProtKB/TrEMBL
  PI31_Prot_N UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report csab:103223213 UniProtKB/TrEMBL
NCBI Gene FBXO7 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 7 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 7 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  PI31_Prot_N UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0D9R7F2 ENTREZGENE, UniProtKB/TrEMBL