APOBEC3C (apolipoprotein B mRNA editing enzyme catalytic subunit 3C) - Rat Genome Database

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Gene: APOBEC3C (apolipoprotein B mRNA editing enzyme catalytic subunit 3C) Chlorocebus sabaeus
Analyze
Symbol: APOBEC3C
Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3C
RGD ID: 18365784
Description: ENCODES a protein that exhibits cytidine deaminase activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN clearance of foreign intracellular DNA (ortholog); negative regulation of viral genome replication (ortholog); positive regulation of gene expression via chromosomal CpG island demethylation (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); P-body (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA dC->dU-editing enzyme APOBEC-3C
RGD Orthologs
Human
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,657,588 - 21,662,061 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,657,702 - 21,661,643 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,095,446 - 104,099,780 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:22726727   PMID:30032202  


Genomics

Comparative Map Data
APOBEC3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,657,588 - 21,662,061 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,657,702 - 21,661,643 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,095,446 - 104,099,780 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
APOBEC3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,014,257 - 39,020,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,014,257 - 39,020,352 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,410,262 - 39,416,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,740,211 - 37,744,789 (+)NCBINCBI36Build 36hg18NCBI36
Build 342237,734,764 - 37,739,323NCBI
Celera2223,212,300 - 23,216,878 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,378,411 - 22,382,770 (+)NCBIHuRef
CHM1_12239,369,230 - 39,373,808 (+)NCBICHM1_1
T2T-CHM13v2.02239,484,669 - 39,490,772 (+)NCBIT2T-CHM13v2.0
APOBEC3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,864,861 - 48,871,513 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,556,399 - 51,562,865 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,924,116 - 19,930,771 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,743,388 - 37,749,725 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,743,388 - 37,749,725 (+)Ensemblpanpan1.1panPan2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 31 18 15
Low 5 2 44
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000004439   ⟹   ENSCSAP00000002694
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1921,657,702 - 21,661,643 (+)Ensembl
RefSeq Acc Id: NM_001345952   ⟹   NP_001332881
RefSeq Status: VALIDATED
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666045104,095,446 - 104,099,780 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001332881 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABY85203 (Get FASTA)   NCBI Sequence Viewer  
  AOR05761 (Get FASTA)   NCBI Sequence Viewer  
  AOR05762 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000002694.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000002694   ⟸   ENSCSAT00000004439
RefSeq Acc Id: NP_001332881   ⟸   NM_001345952
- UniProtKB: A0A0D9R255 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000006402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000004439.1 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro APOBEC/CMP_deaminase_Zn-bd UniProtKB/TrEMBL
  CMP_dCMP_dom UniProtKB/TrEMBL
  Cytidine_deaminase-like UniProtKB/TrEMBL
NCBI Gene APOBEC3C ENTREZGENE
PANTHER DNA DC-DU-EDITING ENZYME APOBEC-3C UniProtKB/TrEMBL
  MRNA EDITING ENZYME UniProtKB/TrEMBL
Pfam NAD2 UniProtKB/TrEMBL
PROSITE CYT_DCMP_DEAMINASES_1 UniProtKB/TrEMBL
  CYT_DCMP_DEAMINASES_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53927 UniProtKB/TrEMBL
UniProt A0A0D9R255 ENTREZGENE, UniProtKB/TrEMBL
  A0A1C9T791_CHLSB UniProtKB/TrEMBL
  A0A1C9T7D7_CHLSB UniProtKB/TrEMBL