AP3B2 (adaptor related protein complex 3 subunit beta 2) - Rat Genome Database

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Gene: AP3B2 (adaptor related protein complex 3 subunit beta 2) Chlorocebus sabaeus
Analyze
Symbol: AP3B2
Name: adaptor related protein complex 3 subunit beta 2
RGD ID: 18357608
Description: INVOLVED IN anterograde axonal transport (ortholog); synaptic vesicle endocytosis (ortholog); ASSOCIATED WITH amenorrhea (ortholog); autistic disorder (ortholog); Bloom syndrome (ortholog); FOUND IN presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adaptor related protein complex 3 beta 2 subunit; AP-3 complex subunit beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1292,943,836 - 2,994,655 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl292,943,919 - 2,994,700 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605944,096,209 - 44,146,590 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AP3B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1292,943,836 - 2,994,655 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl292,943,919 - 2,994,700 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605944,096,209 - 44,146,590 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
AP3B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381582,659,281 - 82,709,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1582,659,281 - 82,710,112 (-)EnsemblGRCh38hg38GRCh38
GRCh371583,328,033 - 83,378,627 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361581,125,088 - 81,175,689 (-)NCBINCBI36Build 36hg18NCBI36
Build 341581,125,088 - 81,175,689NCBI
Celera1561,202,181 - 61,252,080 (+)NCBICelera
Cytogenetic Map15q25.2NCBI
HuRef1559,598,225 - 59,648,196 (-)NCBIHuRef
CHM1_11583,069,649 - 83,120,279 (-)NCBICHM1_1
T2T-CHM13v2.01580,523,517 - 80,574,118 (-)NCBIT2T-CHM13v2.0
Ap3b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,110,147 - 81,143,722 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,110,147 - 81,143,673 (-)EnsemblGRCm39 Ensembl
GRCm38781,460,399 - 81,493,997 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,460,399 - 81,493,925 (-)EnsemblGRCm38mm10GRCm38
MGSCv37788,605,285 - 88,638,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36781,333,912 - 81,367,219 (-)NCBIMGSCv36mm8
Celera778,865,761 - 78,899,589 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.71NCBI
Ap3b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,821,819 - 144,854,533 (-)NCBIGRCr8
mRatBN7.21135,412,580 - 135,445,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,412,580 - 135,445,191 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,327,368 - 143,359,878 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01150,496,780 - 150,529,312 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,409,718 - 143,442,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01143,284,041 - 143,315,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,283,996 - 143,315,633 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01144,226,397 - 144,257,823 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,672,485 - 137,675,472 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,750,890 - 137,783,604 (-)NCBI
Celera1127,463,297 - 127,495,931 (-)NCBICelera
Cytogenetic Map1q31NCBI
Ap3b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541613,927,545 - 13,957,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541613,927,655 - 13,956,589 (+)NCBIChiLan1.0ChiLan1.0
AP3B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21673,176,823 - 73,227,198 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11577,337,464 - 77,387,862 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01562,888,359 - 62,938,758 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11580,557,690 - 80,587,583 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1580,557,967 - 80,607,475 (-)Ensemblpanpan1.1panPan2
AP3B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,509,753 - 54,539,520 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,508,627 - 54,539,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha357,150,469 - 57,183,893 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0354,929,056 - 54,962,786 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl354,929,056 - 54,962,861 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1354,449,324 - 54,482,733 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0354,658,277 - 54,691,744 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,000,840 - 55,034,241 (-)NCBIUU_Cfam_GSD_1.0
Ap3b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640128,997,555 - 129,032,549 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648317,298,291 - 17,337,578 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648317,301,969 - 17,336,962 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP3B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl752,256,159 - 52,294,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1752,202,649 - 52,294,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2757,742,656 - 57,780,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Ap3b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476818,476,447 - 18,507,998 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476818,476,562 - 18,507,933 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 21 60
Low 15 14
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015378   ⟹   ENSCSAP00000013319
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl292,943,919 - 2,994,700 (+)Ensembl
RefSeq Acc Id: XM_007990242   ⟹   XP_007988433
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1292,943,861 - 2,994,655 (+)NCBI
Vero_WHO_p1.0NW_02366605944,096,209 - 44,146,587 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007990243   ⟹   XP_007988434
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1292,943,836 - 2,994,655 (+)NCBI
Vero_WHO_p1.0NW_02366605944,096,209 - 44,146,553 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037987782   ⟹   XP_037843710
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605944,124,825 - 44,146,590 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007988433 (Get FASTA)   NCBI Sequence Viewer  
  XP_007988434 (Get FASTA)   NCBI Sequence Viewer  
  XP_037843710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013319.1
Reference Protein Sequences
RefSeq Acc Id: XP_007988434   ⟸   XM_007990243
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RXI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007988433   ⟸   XM_007990242
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RXI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013319   ⟸   ENSCSAT00000015378
RefSeq Acc Id: XP_037843710   ⟸   XM_037987782
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017286 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015378.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro AP3_beta UniProtKB/TrEMBL
  AP3B_C UniProtKB/TrEMBL
  AP_beta UniProtKB/TrEMBL
  ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Clathrin/coatomer_adapt-like_N UniProtKB/TrEMBL
  Clathrin_app_Ig-like_sf UniProtKB/TrEMBL
NCBI Gene AP3B2 ENTREZGENE
PANTHER AP-3 COMPLEX SUBUNIT BETA-2 UniProtKB/TrEMBL
  PTHR11134 UniProtKB/TrEMBL
Pfam Adaptin_N UniProtKB/TrEMBL
  AP3B1_C UniProtKB/TrEMBL
PIRSF AP3_complex_beta UniProtKB/TrEMBL
SMART AP3B1_C UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF49348 UniProtKB/TrEMBL
UniProt A0A0D9RXI0 ENTREZGENE, UniProtKB/TrEMBL