CDADC1 (cytidine and dCMP deaminase domain containing 1) - Rat Genome Database

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Gene: CDADC1 (cytidine and dCMP deaminase domain containing 1) Chlorocebus sabaeus
Analyze
Symbol: CDADC1
Name: cytidine and dCMP deaminase domain containing 1
RGD ID: 18355932
Description: ENCODES a protein that exhibits cytidine deaminase activity (inferred); hydrolase activity (inferred); importin-alpha family protein binding (inferred); INVOLVED IN cytidine deamination (inferred); DNA cytosine deamination (inferred); ASSOCIATED WITH chromosome 13q14 deletion syndrome (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytidine and dCMP deaminase domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1327,165,870 - 27,212,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl327,177,026 - 27,212,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605716,675,187 - 16,721,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDADC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1327,165,870 - 27,212,179 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl327,177,026 - 27,212,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605716,675,187 - 16,721,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CDADC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381349,247,925 - 49,293,485 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1349,247,925 - 49,293,485 (+)EnsemblGRCh38hg38GRCh38
GRCh371349,822,061 - 49,867,621 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361348,720,099 - 48,765,619 (+)NCBINCBI36Build 36hg18NCBI36
Build 341348,720,103 - 48,765,619NCBI
Celera1330,877,932 - 30,923,465 (+)NCBICelera
Cytogenetic Map13q14.2NCBI
HuRef1330,615,855 - 30,661,391 (+)NCBIHuRef
CHM1_11349,789,604 - 49,835,162 (+)NCBICHM1_1
T2T-CHM13v2.01348,469,229 - 48,514,699 (+)NCBIT2T-CHM13v2.0
Cdadc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391459,796,837 - 59,835,433 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1459,796,837 - 59,835,408 (-)EnsemblGRCm39 Ensembl
GRCm381459,559,386 - 59,597,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1459,559,388 - 59,597,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv371460,178,225 - 60,216,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361458,513,497 - 58,552,067 (-)NCBIMGSCv36mm8
Celera1457,361,094 - 57,399,657 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1431.48NCBI
Cdadc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81537,902,789 - 37,934,853 (-)NCBIGRCr8
mRatBN7.21533,726,590 - 33,755,611 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1533,723,435 - 33,755,576 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1535,588,929 - 35,617,872 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01536,739,609 - 36,768,552 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01535,187,727 - 35,216,726 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01539,865,094 - 39,894,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1539,882,210 - 39,893,979 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01543,686,831 - 43,715,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41538,675,339 - 38,687,199 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11538,691,039 - 38,702,899 (-)NCBI
Celera1533,449,998 - 33,461,858 (-)NCBICelera
Cytogenetic Map15p12NCBI
Cdadc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554312,725,742 - 2,767,664 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554312,724,988 - 2,767,539 (+)NCBIChiLan1.0ChiLan1.0
CDADC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21450,686,411 - 50,734,619 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11349,337,650 - 49,385,853 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01330,386,671 - 30,432,112 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11349,138,359 - 49,183,639 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1349,138,498 - 49,186,541 (+)Ensemblpanpan1.1panPan2
CDADC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1222,443,459 - 2,489,147 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl222,436,206 - 2,489,016 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha222,472,664 - 2,518,110 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,435,070 - 2,480,586 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,408,547 - 2,480,562 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1222,343,275 - 2,388,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0222,392,393 - 2,437,847 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,411,044 - 2,456,499 (-)NCBIUU_Cfam_GSD_1.0
Cdadc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945158,852,547 - 158,911,922 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365652,336,744 - 2,387,195 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365652,336,613 - 2,395,816 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDADC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1118,458,301 - 18,518,146 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11118,467,508 - 18,518,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21118,857,586 - 18,916,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Cdadc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247485,426,215 - 5,467,082 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247485,420,395 - 5,467,215 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 7 8
Low 29 18 52
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007960389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000015818   ⟹   ENSCSAP00000013746
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl327,177,026 - 27,212,171 (+)Ensembl
RefSeq Acc Id: XM_007960389   ⟹   XP_007958580
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1327,165,870 - 27,212,179 (+)NCBI
Vero_WHO_p1.0NW_02366605716,675,187 - 16,721,252 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007958580 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013746
  ENSCSAP00000013746.1
Reference Protein Sequences
RefSeq Acc Id: XP_007958580   ⟸   XM_007960389
- UniProtKB: A0A0D9RYQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013746   ⟸   ENSCSAT00000015818


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015818.1 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro APOBEC/CMP_deaminase_Zn-bd UniProtKB/TrEMBL
  CMP_dCMP_dom UniProtKB/TrEMBL
  Cytidine_deaminase-like UniProtKB/TrEMBL
  dCMP_deaminase-rel UniProtKB/TrEMBL
  Deoxycytidylate_deaminase_dom UniProtKB/TrEMBL
NCBI Gene CDADC1 ENTREZGENE
PANTHER DEOXYCYTIDYLATE DEAMINASE UniProtKB/TrEMBL
  PTHR11086 UniProtKB/TrEMBL
Pfam dCMP_cyt_deam_1 UniProtKB/TrEMBL
PROSITE CYT_DCMP_DEAMINASES_1 UniProtKB/TrEMBL
  CYT_DCMP_DEAMINASES_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53927 UniProtKB/TrEMBL
UniProt A0A0D9RYQ7 ENTREZGENE, UniProtKB/TrEMBL