ETV6 (ETS variant transcription factor 6) - Rat Genome Database

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Gene: ETV6 (ETS variant transcription factor 6) Chlorocebus sabaeus
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Symbol: ETV6
Name: ETS variant transcription factor 6
RGD ID: 18344676
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell differentiation (ortholog); mesenchymal cell apoptotic process (ortholog); neurogenesis (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); autosomal dominant intellectual developmental disorder 6 (ortholog); FOUND IN cytosol (inferred); nucleolus (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ETS variant 6; transcription factor ETV6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11111,567,522 - 11,812,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1111,567,632 - 11,811,716 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606923,507,501 - 23,755,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ETV6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11111,567,522 - 11,812,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1111,567,632 - 11,811,716 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606923,507,501 - 23,755,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ETV6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381211,649,674 - 11,895,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1211,649,674 - 11,895,377 (+)EnsemblGRCh38hg38GRCh38
GRCh371211,802,608 - 12,048,311 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361211,694,055 - 11,939,603 (+)NCBINCBI36Build 36hg18NCBI36
Build 341211,694,054 - 11,939,590NCBI
Celera1216,945,067 - 17,191,403 (+)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1211,670,991 - 11,813,778 (+)NCBIHuRef
CHM1_11211,768,106 - 12,013,345 (+)NCBICHM1_1
T2T-CHM13v2.01211,518,944 - 11,764,496 (+)NCBIT2T-CHM13v2.0
Etv6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396134,012,663 - 134,247,121 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6134,012,663 - 134,247,121 (+)EnsemblGRCm39 Ensembl
GRCm386134,035,700 - 134,270,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6134,035,700 - 134,270,158 (+)EnsemblGRCm38mm10GRCm38
MGSCv376133,985,725 - 134,220,176 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366134,001,400 - 134,235,851 (+)NCBIMGSCv36mm8
Celera6136,977,650 - 137,213,190 (+)NCBICelera
Cytogenetic Map6G1NCBI
cM Map664.58NCBI
Etv6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84168,580,405 - 168,819,817 (+)NCBIGRCr8
mRatBN7.24166,849,031 - 167,085,211 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4166,847,686 - 167,084,992 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4173,142,448 - 173,378,418 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04168,925,517 - 169,161,489 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04167,551,450 - 167,787,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04167,754,684 - 167,992,370 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4167,754,525 - 167,992,168 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04230,278,004 - 230,512,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44170,909,412 - 171,150,381 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4155,553,221 - 155,688,674 (+)NCBICelera
Cytogenetic Map4q43NCBI
Etv6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554138,698,415 - 8,909,299 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554138,698,412 - 8,912,011 (+)NCBIChiLan1.0ChiLan1.0
ETV6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21016,964,080 - 17,360,417 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11217,116,005 - 17,357,174 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01211,675,955 - 11,920,913 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11212,035,107 - 12,179,537 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1211,844,939 - 12,179,537 (+)Ensemblpanpan1.1panPan2
ETV6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12734,351,206 - 34,587,060 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2734,343,390 - 34,587,060 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2711,860,742 - 12,096,549 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02734,658,546 - 34,894,957 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2734,658,567 - 34,894,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12734,549,124 - 34,785,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02734,499,384 - 34,735,770 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02711,589,902 - 11,826,246 (+)NCBIUU_Cfam_GSD_1.0
Etv6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494595,600,416 - 95,729,629 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365875,330,665 - 5,457,264 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365875,328,467 - 5,457,260 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETV6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl560,523,433 - 60,776,750 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1560,523,530 - 60,776,792 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2563,079,493 - 63,323,664 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Etv6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475225,913,456 - 26,131,164 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475225,916,942 - 26,131,380 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 15 13
Low 21 20 47
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000006707   ⟹   ENSCSAP00000004906
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1111,567,632 - 11,811,716 (+)Ensembl
RefSeq Acc Id: XM_007967682   ⟹   XP_007965873
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11111,567,522 - 11,812,292 (+)NCBI
Vero_WHO_p1.0NW_02366606923,507,501 - 23,755,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007967683   ⟹   XP_007965874
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11111,567,616 - 11,812,292 (+)NCBI
Vero_WHO_p1.0NW_02366606923,507,501 - 23,755,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007967684   ⟹   XP_007965875
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11111,567,620 - 11,812,292 (+)NCBI
Vero_WHO_p1.0NW_02366606923,507,501 - 23,755,706 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007965873 (Get FASTA)   NCBI Sequence Viewer  
  XP_007965874 (Get FASTA)   NCBI Sequence Viewer  
  XP_007965875 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004906
  ENSCSAP00000004906.1
RefSeq Acc Id: XP_007965873   ⟸   XM_007967682
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R8G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007965874   ⟸   XM_007967683
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007965875   ⟸   XM_007967684
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCSAP00000004906   ⟸   ENSCSAT00000006707


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008644 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006707.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  Pointed_dom UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report csab:103218636 UniProtKB/TrEMBL
NCBI Gene ETV6 ENTREZGENE
PANTHER PTHR11849 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR ETV6 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
UniProt A0A0D9R8G7 ENTREZGENE, UniProtKB/TrEMBL