RAB32 (RAB32, member RAS oncogene family)

Gene: RAB32 (RAB32, member RAS oncogene family) Chlorocebus sabaeus

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Symbol:

RAB32

Name:

RAB32, member RAS oncogene family

RGD ID:

18343284

Description:

ENCODES a protein that exhibits AP-1 adaptor complex binding (ortholog); AP-2 adaptor complex binding (ortholog); AP-3 adaptor complex binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); endosome to melanosome transport (ortholog); melanosome assembly (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Experimental Liver Cirrhosis (ortholog); fragile X syndrome (ortholog); FOUND IN early endosome (ortholog); early endosome lumen (ortholog); endoplasmic reticulum (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein Rab-32

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	25,265,831 - 25,281,106 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	201,227,806 - 201,242,889 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic contact dermatitis (ISO)

Experimental Liver Cirrhosis (ISO)

fragile X syndrome (ISO)

genetic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

leprosy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation (ISO)

endosome to lysosome transport (IEA)

endosome to melanosome transport (ISO)

melanosome assembly (ISO)

mitochondrion organization (ISO)

phagosome maturation (ISO)

phagosome-lysosome fusion (IEA)

protein localization to membrane (ISO)

vesicle-mediated transport (IEA)

Cellular Component

early endosome (ISO)

early endosome lumen (ISO)

endoplasmic reticulum (ISO)

Golgi apparatus (IEA)

intracellular membrane-bounded organelle (IEA)

late endosome (IEA)

lysosome (IEA)

melanosome (IEA)

melanosome membrane (ISO)

membrane (IEA)

mitochondria-associated endoplasmic reticulum membrane contact site (ISO)

mitochondrial outer membrane (ISO)

mitochondrion (ISO)

phagocytic vesicle (IEA)

trans-Golgi network (IEA)

vesicle (IEA)

Molecular Function

AP-1 adaptor complex binding (ISO)

AP-2 adaptor complex binding (ISO)

AP-3 adaptor complex binding (ISO)

BLOC-2 complex binding (ISO)

GTP binding (IEA)

GTP-dependent protein binding (ISO)

GTPase activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

RAB32
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	25,265,831 - 25,281,106 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666040	201,227,806 - 201,242,889 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

RAB32
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	146,543,833 - 146,554,953 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	146,543,833 - 146,554,953 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	146,864,969 - 146,876,089 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	146,906,521 - 146,917,782 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	146,906,520 - 146,917,779	NCBI
Celera	6	147,605,264 - 147,616,521 (+)	NCBI		Celera
Cytogenetic Map	6	q24.3	NCBI
HuRef	6	144,428,711 - 144,439,665 (+)	NCBI		HuRef
CHM1_1	6	147,128,062 - 147,139,320 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	147,737,054 - 147,748,175 (+)	NCBI		T2T-CHM13v2.0

Rab32
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	10,420,783 - 10,433,951 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	10,420,746 - 10,434,009 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	10,545,039 - 10,558,207 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	10,545,002 - 10,558,265 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	10,264,837 - 10,278,005 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	10,235,229 - 10,248,397 (-)	NCBI		MGSCv36	mm8
Celera	10	10,440,276 - 10,453,408 (-)	NCBI		Celera
Cytogenetic Map	10	A1	NCBI
cM Map	10	3.44	NCBI

Rab32
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	6,766,448 - 6,781,258 (-)	NCBI		GRCr8
mRatBN7.2	1	4,946,193 - 4,961,003 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	4,945,036 - 4,960,934 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	4,623,280 - 4,644,402 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	10,623,631 - 10,644,753 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	4,905,472 - 4,926,595 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	4,638,663 - 4,653,220 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	4,637,491 - 4,653,210 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	6,299,748 - 6,314,539 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	5,203,908 - 5,218,416 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	3,479,984 - 3,494,673 (-)	NCBI		Celera
Cytogenetic Map	1	p13	NCBI

Rab32
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	14,171,123 - 14,177,577 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955436	14,171,123 - 14,177,255 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAB32
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	166,541,048 - 166,561,393 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	164,438,382 - 164,453,907 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	144,339,323 - 144,354,885 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

RAB32
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	37,706,809 - 37,719,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	37,712,142 - 37,718,266 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	38,588,880 - 38,611,342 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	37,866,146 - 37,889,054 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	37,865,534 - 37,889,049 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	37,743,864 - 37,766,334 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	37,615,197 - 37,637,672 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	37,945,159 - 37,967,854 (+)	NCBI		UU_Cfam_GSD_1.0

Rab32
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	132,783,627 - 132,799,818 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936489	35,620 - 51,809 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB32
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	19,075,271 - 19,097,870 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	19,076,301 - 19,097,647 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	21,320,352 - 21,341,852 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Rab32
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624753	7,900,267 - 7,917,854 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624753	7,900,027 - 7,917,944 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	2
Low	34	20	60
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008006729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_008006729 ⟹ XP_008004920

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	13	25,265,831 - 25,281,106 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	201,227,806 - 201,242,889 (-)	NCBI

Sequence:

show sequence

GCACTGGCGGGTTCCGGGTCCTGTGACCGGTCAGGCGGCGTCAGCGGGCGCGGCGGAGGGCGGG
CCGGCCTCGGGGGAGTTTCCGCGGCCGCCGGGGGCGGGGCGGGAGAGCGCGAGGCCGGGCGGGA
GGCCAGACTCGGAGCCCCGGCACGCCGGACAGTCGCAGCGCTCATGGCGGGCGGGGGAGCCGGG
GACCCCGGCCTGGGGGCGGCTGCCGCCCCGGCGCCCGAGACCCGCGAGCACCTCTTCAAGGTGC
TGGTTATCGGCGAGCTTGGAGTGGGCAAGACCAGCATCATCAAGCGCTACGTCCACCAGCTCTT
CTCCCAGCACTACCGGGCCACCATCGGGGTGGACTTCGCCCTCAAGGTCCTCAACTGGGACAGC
AGGACTCTGGTGCGCCTGCAGCTGTGGGACATCGCGGGGCAGGAGCGATTTGGCAACATGACCC
GAGTATACTACAAGGAAGCTGTTGGTGCTTTTGTAGTCTTTGATATATCAAGAAGTTCTACATT
TGAGGCAGTCTTAAAATGGAAAAGTGATCTGGATAGTAAAGTTCATCTTCCAAATGGCAGCCCT
ATCCCTGCCGTCCTCTTGGCTAACAAATGTGACCAGAACAAGGACAGTAGCCAGAGTCCTTCCC
AGATGGACCAGTTCTGCAAAGAACATGGCTTCGCCGGATGGTTTGAAACCTCTGCAAAGGATAA
CATAAACATAGAGGAAGCTGCCCGGTTCCTAGTGGAGAAGATTCTTGCAAACCACCAAAGCTTT
CCTAATGAAGAAAACGATGTGGGCAAAATTAAGCTAGATCAAGAGACCTTGAGAGCAGAGAGCA
AATCCCAGTGTTGCTGATAGGGCTTCTGCTTCTCTCGTGTGTGCCTCAGCTCTGAAGAAGTTCC
TGAGAATGGGTTATGGATGTCATGTTAGCTGTGAGTCTTCCCACAGGTGGCACTTCAAAAGGCA
GTACCACTGGGTGCCTGCACTTATTTGAAAATGGAACTTTGGGAGAAGTATCCCTGCCAGTGGC
TCTGTAACTTAACAGATGACAATTAGGCTTTTGTCATTGTCGCCGTCATATGGAAGATAATGTT
TACATCCTTTTAAACATCTTTTTATATGACAGTTCCTTAGGATTTGGTAAGCCTTCCAAGTTGT
AGCTTTTAATGTAAGTGCTGGGGTGGTAATAAAATGTTACCTCCAGTTTTATGGTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008004920	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000013184
	ENSCSAP00000013184.1

RefSeq Acc Id:	XP_008004920 ⟸ XM_008006729
- UniProtKB:	A0A0D9RX45 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000017145	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000015239.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Rab29/Rab38/Rab32	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
KEGG Report	csab:103240202	UniProtKB/TrEMBL
NCBI Gene	RAB32	ENTREZGENE
PANTHER	RAB FAMILY	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN RAB-32 ISOFORM X1	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0D9RX45	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD