DUS1L (dihydrouridine synthase 1 like) - Rat Genome Database

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Gene: DUS1L (dihydrouridine synthase 1 like) Chlorocebus sabaeus
Analyze
Symbol: DUS1L
Name: dihydrouridine synthase 1 like
RGD ID: 18342924
Description: ENCODES a protein that exhibits flavin adenine dinucleotide binding (inferred); oxidoreductase activity (inferred); tRNA dihydrouridine synthase activity (inferred); INVOLVED IN tRNA dihydrouridine synthesis (inferred); tRNA processing (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,958,826 - 73,966,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,959,060 - 73,966,786 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,497,401 - 45,508,098 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DUS1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,958,826 - 73,966,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,959,060 - 73,966,786 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,497,401 - 45,508,098 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DUS1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381782,057,506 - 82,065,804 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1782,057,506 - 82,065,887 (-)EnsemblGRCh38hg38GRCh38
GRCh371780,015,382 - 80,023,680 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,609,040 - 77,616,969 (-)NCBINCBI36Build 36hg18NCBI36
Celera1776,609,999 - 76,617,972 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,415,868 - 75,423,755 (-)NCBIHuRef
CHM1_11780,101,963 - 80,109,913 (-)NCBICHM1_1
T2T-CHM13v2.01782,924,664 - 82,932,962 (-)NCBIT2T-CHM13v2.0
Dus1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,678,385 - 120,687,254 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,680,027 - 120,687,229 (-)EnsemblGRCm39 Ensembl
GRCm3811120,787,559 - 120,796,427 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,789,201 - 120,796,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,650,516 - 120,657,709 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,605,292 - 120,612,485 (-)NCBIMGSCv36mm8
Celera11132,525,547 - 132,532,740 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.54NCBI
Dus1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,553,841 - 106,560,977 (-)NCBIGRCr8
mRatBN7.210106,055,519 - 106,062,656 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10106,055,519 - 106,062,781 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10111,159,542 - 111,166,612 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,622,580 - 110,629,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,975,966 - 105,983,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,972,018 - 109,979,113 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,972,037 - 109,979,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,563,524 - 109,570,777 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,599,312 - 104,606,369 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Dus1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,097,062 - 1,104,918 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,097,255 - 1,104,918 (+)NCBIChiLan1.0ChiLan1.0
DUS1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,593,082 - 98,601,108 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,493,801 - 103,501,832 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,462,543 - 76,470,556 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,167,347 - 82,175,253 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,167,347 - 82,175,253 (-)Ensemblpanpan1.1panPan2
DUS1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19255,939 - 261,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9256,214 - 261,655 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha9858,814 - 864,224 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09850,263 - 855,675 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9850,271 - 855,413 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19875,208 - 880,618 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,002,124 - 1,007,532 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,080,645 - 1,086,055 (+)NCBIUU_Cfam_GSD_1.0
Dus1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602841,186 - 848,341 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,559,480 - 5,570,829 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,563,609 - 5,570,712 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUS1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12946,048 - 951,776 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112945,459 - 951,720 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Dus1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,895,472 - 10,902,772 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,895,983 - 10,902,804 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 17 17
Low 19 20 43
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000000175   ⟹   ENSCSAP00000015878
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1673,959,060 - 73,966,786 (-)Ensembl
RefSeq Acc Id: XM_008013332   ⟹   XP_008011523
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,958,826 - 73,966,845 (-)NCBI
Vero_WHO_p1.0NW_02366607745,499,647 - 45,508,098 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008013333   ⟹   XP_008011524
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,958,826 - 73,966,931 (-)NCBI
Vero_WHO_p1.0NW_02366607745,499,644 - 45,508,098 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008013334   ⟹   XP_008011525
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11673,959,091 - 73,966,846 (-)NCBI
Vero_WHO_p1.0NW_02366607745,499,647 - 45,508,098 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037993401   ⟹   XP_037849329
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,497,401 - 45,508,098 (-)NCBI
RefSeq Acc Id: XM_037993402   ⟹   XP_037849330
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,500,587 - 45,508,098 (-)NCBI
RefSeq Acc Id: XM_037993403   ⟹   XP_037849331
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607745,500,586 - 45,508,098 (-)NCBI
RefSeq Acc Id: XP_008011524   ⟸   XM_008013333
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S4T9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008011523   ⟸   XM_008013332
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008011525   ⟸   XM_008013334
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCSAP00000015878   ⟸   ENSCSAT00000000175
RefSeq Acc Id: XP_037849329   ⟸   XM_037993401
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037849331   ⟸   XM_037993403
- Peptide Label: isoform X6
RefSeq Acc Id: XP_037849330   ⟸   XM_037993402
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002157 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000175.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  DUS-like_FMN-bd UniProtKB/TrEMBL
  tRNA_hU_synthase_CS UniProtKB/TrEMBL
NCBI Gene DUS1L ENTREZGENE
PANTHER TRNA-DIHYDROURIDINE SYNTHASE UniProtKB/TrEMBL
  TRNA-DIHYDROURIDINE(16/17) SYNTHASE [NAD(P)(+)]-LIKE UniProtKB/TrEMBL
Pfam Dus UniProtKB/TrEMBL
PROSITE UPF0034 UniProtKB/TrEMBL
Superfamily-SCOP FMN-linked oxidoreductases UniProtKB/TrEMBL
UniProt A0A0D9S4T9 ENTREZGENE, UniProtKB/TrEMBL