LOC128924767 (STARR-positive B cell enhancer ABC_E4536) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: LOC128924767 (STARR-positive B cell enhancer ABC_E4536) Mus musculus
Analyze
Symbol: LOC128924767
Name: STARR-positive B cell enhancer ABC_E4536
RGD ID: 163693291
Description: This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. A subregion was identified as a candidate cis-regulatory module (CRM) in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. That CRM was validated as an active enhancer by high-throughput CapStarr-seq reporter assays showing weak activity in P5424 T cells. [provided by RefSeq, Oct 2023]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: CapStarr-seq enhancer MGSCv37_chr3:21886739-21886926; Rr367416
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39322,041,900 - 22,042,201 (+)NCBIGRCm39GRCm39mm39
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:25872643   PMID:31873292   PMID:31873293  


Genomics

Variants

.
Variants in LOC128924767
12 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301256Skmw1_mskeletal muscle weight 1 (mouse)Not determined3125786432Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
12798540Scvg2_msubcutaneous vessel growth QTL 2 (mouse)3744981526249645Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
25671383Hrsq1_mhost response to SARS QTL 1, vascular cuffing (mouse)31844095426823641Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_150519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC128924767 ENTREZGENE
PhenoGen LOC128924767 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-10 LOC128924767  STARR-positive B cell enhancer ABC_E4536  LOC128924767  CapStarr-seq enhancer MGSCv37_chr3:21886739-21886926  Symbol and/or name change 5135510 APPROVED